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LXRX · Lexicon Pharmaceuticals, Inc. · Shareholders & Ownership

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$1.56 -0.02 (-1.27%) At close · Oct 21
Market Cap
$703.03M
Shares
444.96M
Volume · Oct 21 1.4M Avg daily vol (3M) 2.78M

Every disclosed holder of LXRX in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

Who Owns LXRX

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

No chart: the summed disclosures exceed shares outstanding, so they are not parts of one whole.

Holder group Shares % Out
Institutional (13F) 364,837,699 81.99%
Insiders (Forms 3, 4, 5) 58,437,573 13.13%
13D/G-only blocks 136,180,481 30.61%
Remaining 114,499,819 -25.73%
Registered funds (N-PORT, not summed) 57,473,649 12.92%

Shares outstanding: 444,955,934, the issuer's latest cover-page count restated onto today's split basis.

Remaining is negative: the summed disclosures exceed shares outstanding, as when filings are dated at different times or holders that do not disclose their links count the same shares. It is flagged, not clipped.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of LXRX

# Holder Shares
1
Artal Group S.A.
13F CIK 1053906 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
175,156,062
1.1
Artal Participations S.a r.l.
Insider CIK 2048403 · Apr 30, 2026
Director, 10% Owner, issuer-wide, not summed
175,156,062
2
Artal International S.C.A.
13D CIK 1404570 · Dec 5, 2024
136,180,481
3
FMR LLC
13F CIK 315066 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
51,782,045
3.1
FMR LLC
13G CIK 315066 · Holding company · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
51,782,044
3.2
Fidelity Growth Company Fund
Fund S000007119 · Registered fund · May 31, 2026
Fidelity Mt. Vernon Street Trust, not summed
16,542,000
3.3
Fidelity Growth Company K6 Fund
Fund S000065696 · Registered fund · May 31, 2026
Fidelity Mt. Vernon Street Trust, not summed
4,887,306
3.4
Fidelity Series Growth Company Fund
Fund S000042626 · Registered fund · May 31, 2026
Fidelity Mt. Vernon Street Trust, not summed
3,977,693
3.5
Fidelity Small Cap Index Fund
Fund S000033638 · Registered fund · Jul 31, 2026
Fidelity Salem Street Trust, not summed
2,722,989
4
DEBBANE RAYMOND
Insider CIK 1053890 · Jun 3, 2026
Director, issuer-wide
51,750,221
5
Siren, L.L.C.
13F CIK 2005245 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
44,303,518
6
Invus Public Equities, L.P.
13D CIK 2005369 · Unknown · Apr 30, 2026
not summed
42,765,057
6.1
Invus Global Management, LLC
Insider CIK 2005369 · Feb 2, 2026
Director, 10% Owner, issuer-wide
1,752,834
7
Sessa Capital IM, L.P.
13F CIK 1595849 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
18,960,836
8
BlackRock, Inc.
13F CIK 2012383 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
17,348,741
8.1
iShares Russell 2000 ETF
Fund S000004344 · Registered fund · Jun 30, 2026
iShares Trust, not summed
6,209,944
8.2
iShares Russell 2000 Growth ETF
Fund S000004343 · Registered fund · Jun 30, 2026
iShares Trust, not summed
2,278,291
8.3
iShares Micro-Cap ETF
Fund S000004439 · Registered fund · Jun 30, 2026
iShares Trust, not summed
835,530
8.4
Master Small Cap Index Series
Fund S000002716 · Registered fund · Jun 30, 2026
Quantitative Master Series LLC, not summed
465,227
8.5
iShares Russell 3000 ETF
Fund S000004341 · Registered fund · Jun 30, 2026
iShares Trust, not summed
83,387
9
VANGUARD CAPITAL MANAGEMENT LLC
13F CIK 2100119 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
9,901,208
10
Point72 Asset Management, L.P.
13F CIK 1603466 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
8,251,325
11
VANGUARD TOTAL STOCK MARKET INDEX FUND
Fund S000002848 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
7,083,651
12
GEODE CAPITAL MANAGEMENT, LLC
13F CIK 1214717 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
6,244,372
13
STATE STREET CORP
13F CIK 93751 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
4,917,769
13.1
State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF
Fund S000012321 · Registered fund · Jun 30, 2026
SPDR SERIES TRUST, not summed
1,121,988
13.2
STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO
Fund S000050332 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
74,400
13.3
State Street Total Return V.I.S. Fund
Fund S000001637 · Registered fund · Jun 30, 2026
STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed
6,282
13.4
State Street Balanced Index Fund
Fund S000082802 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
2,116
14
VANGUARD EXTENDED MARKET INDEX FUND
Fund S000002841 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
2,567,310
15
VANGUARD PORTFOLIO MANAGEMENT LLC
13F CIK 2100121 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
2,357,749
16
NORTHERN TRUST CORP
13F CIK 73124 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
1,968,619
16.1
Small Cap Index Fund
Fund S000001245 · Registered fund · Jun 30, 2026
Northern Funds, not summed
125,581
16.2
Small Cap Core Fund
Fund S000001244 · Registered fund · Jun 30, 2026
Northern Funds, not summed
8,328
17
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F CIK 884546 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,956,775
17.1
Schwab U.S. Small-Cap ETF
Fund S000026636 · Registered fund · May 31, 2026
SCHWAB STRATEGIC TRUST, not summed
1,032,223
17.2
Schwab Small-Cap Index Fund
Fund S000005912 · Registered fund · Jul 31, 2026
SCHWAB CAPITAL TRUST, not summed
604,413
17.3
Schwab Total Stock Market Index Fund
Fund S000005913 · Registered fund · Jul 31, 2026
SCHWAB CAPITAL TRUST, not summed
150,000
17.4
Schwab U.S. Broad Market ETF
Fund S000026631 · Registered fund · May 31, 2026
SCHWAB STRATEGIC TRUST, not summed
110,085
18
VANGUARD FIDUCIARY TRUST CO
13F CIK 933478 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
1,634,571
19
CITADEL ADVISORS LLC
13F CIK 1423053 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,601,182
20
Avicenna Life Sci Master Fund LP
Insider CIK 2110935 · Feb 2, 2026
Director, 10% Owner, issuer-wide
1,538,462
21
Ishara Investments LP
13F CIK 2111609 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,271,000
22
MILLENNIUM MANAGEMENT LLC
13F CIK 1273087 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,134,229
23
RENAISSANCE TECHNOLOGIES LLC
13F CIK 1037389 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,127,000
24
MACKENZIE FINANCIAL CORP
13F CIK 919859 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
963,354
25
ADAR1 Capital Management, LLC
13F CIK 1940272 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
750,000
26
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F CIK 1446194 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
696,776
27
ACADIAN ASSET MANAGEMENT LLC
13F CIK 916542 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
696,617
28
UBS Group AG
13F CIK 1610520 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
684,713
29
TWO SIGMA INVESTMENTS, LP
13F CIK 1179392 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
643,444
30
Nuveen, LLC
13F CIK 1871926 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
586,664
30.1
Nuveen Small Cap Blend Index Fund
Fund S000005367 · Registered fund · Jul 31, 2026
TIAA-CREF Funds, not summed
329,641
30.2
Nuveen Equity Index Fund
Fund S000005360 · Registered fund · Jul 31, 2026
TIAA-CREF Funds, not summed
188,321
30.3
TIAA Separate Account VA-1 - Stock Index Account
Fund S000005098 · Registered fund · Jun 30, 2026
TIAA Separate Account VA-1, not summed
4,765
31
Bank of New York Mellon Corp
13F CIK 1390777 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
568,706
32
VANGUARD HEALTH CARE INDEX FUND
Fund S000004450 · Registered fund · May 31, 2026
VANGUARD WORLD FUND, not summed
544,199
33
Invesco Ltd.
13F CIK 914208 · Investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
508,071
33.1
Invesco RAFI US 1500 Small-Mid ETF
Fund S000013120 · Registered fund · Jul 31, 2026
Invesco Exchange-Traded Fund Trust, not summed
323,460
33.2
Invesco NASDAQ Future Gen 200 ETF
Fund S000077288 · Registered fund · May 31, 2026
Invesco Exchange-Traded Fund Trust II, not summed
52,338
34
GOLDMAN SACHS GROUP INC
13F CIK 886982 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
485,546
34.1
Goldman Sachs Absolute Return Tracker Fund
Fund S000020314 · Registered fund · Jun 30, 2026
GOLDMAN SACHS TRUST, not summed
74,108
35
Compagnie Lombard Odier SCmA
13F CIK 1615423 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
480,000
36
Crum Brian T
Insider CIK 1792747 · Feb 28, 2026
SVP, General Counsel & Secr., issuer-wide
428,802
37
BANK OF AMERICA CORP /DE/
13F CIK 70858 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
421,299
38
GSA CAPITAL PARTNERS LLP
13F CIK 1362033 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
397,219
39
BARCLAYS PLC
13F CIK 312069 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
387,483
40
Amouyal Philippe
Insider CIK 1376854 · Jun 3, 2026
Director, issuer-wide
374,486
41
XTX Topco Ltd
13F CIK 1828301 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
357,877
42
MAIN ALAN J
Insider CIK 1227372 · Feb 28, 2025
EVP, Innov & Chem Sciences, issuer-wide
339,104
43
Granowitz Craig B
Insider CIK 1876655 · Feb 28, 2026
SVP, Chief Medical Officer, issuer-wide
323,430
44
Exton Michael
Insider CIK 2029249 · Feb 28, 2026
Director, Chief Executive Officer, issuer-wide
298,432
45
Janney Montgomery Scott LLC
13F CIK 1329948 · Investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
295,548
46
SOBECKI CHRISTOPHER J
Insider CIK 1053892 · Jun 3, 2026
Director, issuer-wide
293,177
47
McDermott Wendy
Insider CIK 1902760 · Feb 28, 2026
SVP, Human Resources, issuer-wide
277,945
48
EQ/2000 Managed Volatility Portfolio
Fund S000025800 · Registered fund · Jun 30, 2026
EQ Advisors Trust, not summed
267,373
49
CANADA PENSION PLAN INVESTMENT BOARD
13F CIK 1283718 · Non-US institution · Jun 30, 2026
carried, not yet filed for the newest quarter
257,900
50
RHUMBLINE ADVISERS
13F CIK 1115418 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
256,885

14 more nested rows are not shown here; Every filing lists them all.

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 208 holders

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Key facts CIK 1062822 CUSIP 528872302 13F (30d) 10 filings 10 filers Visit website Investor relations