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LXRX · Lexicon Pharmaceuticals, Inc.

Track LXRX — free
$1.88 -0.01 (-0.27%) At close · Sep 30
Market Cap
$798.70M
Shares
444.96M
Volume · Sep 30 1.74M Avg daily vol (3M) 2.96M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$1.88 Open$1.89 Day$1.84–1.95 52W close$1.14–2.64 Avg vol 30d3.1M Short int28.8M · 6.5% float · 13.4d Short vol47% Last earningsAug 6, 2026 DataJan 2020–Sep 2026 Filing10-Q · Aug 6

Up next

Next earnings call
Nov 6, 2026 Est · unconfirmed · in 5 wks
filed Aug 6, 2026
call held Aug 6, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$41.47M
Trailing 12 months
Net income (TTM)
−$61.12M
Trailing 12 months
Revenue growth YoY
-97.6%
Year over year
Operating margin
-131.4%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$139.17M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+20.4%
Year over year · more shares
Price change (1Y)
+35.3%
Trailing year
Short interest
6.5%
Latest settlement · 13.4 days to cover
View all 115 metrics

AI Brief

Q2 FY26 earnings call · Aug 6, 2026
Q2 FY26

TL;DR. Lexicon completed enrollment (significantly over-enrolled) in its Phase 3 SONATA-HCM study of sotagliflozin in HCM, with top-line data expected in Q1 2027, and reiterated 2026 operating expense guidance of $100-$110 million; however, ZYNQUISTA NDA resubmission in type 1 diabetes has shifted to Q4 2026, described as a slight delay from prior timeline.

Bullish
  • + Completed and significantly over-enrolled Phase 3 SONATA-HCM study, with top-line data expected Q1 2027
  • + Steno-1 study nearing FDA exposure and DKA thresholds, supporting ZYNQUISTA NDA resubmission in Q4 2026
  • + Novo Nordisk progressing LX9851 Phase 1, with potential third $10 million milestone payment later this year
  • + Viatris expanding ex-U.S./Europe regulatory approvals and submissions for sotagliflozin in heart failure
Bearish
  • − ZYNQUISTA NDA resubmission shifted to Q4 2026, a slight delay from prior timeline
  • − Q2 2026 net loss of $31.8 million vs. net income of $3.3 million in prior year quarter, including $4.3 million loss on early extinguishment of debt

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Sell Momentum Neutral Sentiment Bullish Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 16.3 · calm Equity put/call 0.53
Technical
price trend
Sell
50 / 200-day cross No cross
Price vs 200-day avg +2%
above
Price vs 50-day avg −15%
below
RSI (14) 37
neutral
MACD trend Negative
52-week position 49%
mid-range
Momentum
relative strength
Neutral
1-month return −14%
trailing
6-month return +7%
trailing
YTD return +63%
this year
Relative strength −6%
vs S&P · 6-mo
Sentiment
smart money
Bullish
Trend (MA cross) No cross
50d $2 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+9% holders QoQ · +43 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
6.47% of float · ▼ -2.4% MoM · 13.4 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
150 holders — near 3-yr high, broad support
Squeeze score 65
elevated · 0–100
Fundamentals
Strong
Revenue growth +60%
Y/Y
EPS growth +78%
Y/Y
Free cash flow $-67.9M
Balance sheet $19.7M
net debt
Quant / Vol
risk profile
Very High
Volatility 77%
annualized · 1-yr
Max drawdown −34%
past year
ATR 6.7%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the Earnings Call filed Jun 30, 2026
Operating expenses · 2026 $100M – $110M
R&D · 2026 $63M – $68M
SG&A · 2026 $37M – $42M

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Sell
2 · 3 · 1
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+2% Bullish
Price vs 50-day avg
−15% Bearish
RSI (14)
37 Neutral
MACD trend
Negative Bearish
52-week position
49% Neutral
Market signals — smart money & positioning
Bullish · 3 of 6
Trend (MA cross) No cross
50d $2 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+9% holders QoQ · +43 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
6.47% of float · ▼ -2.4% MoM · 13.4 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
150 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $1 Now $2 · 49% Range high $3
vs 200-day avg +2% vs 50-day avg -15%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
LXRX
Lexicon Pharmaceuticals, Inc.
this stock
$798.70M +63.0% +60.2% — 6.5%
VRTX
Vertex Pharmaceuticals Inc / Ma
$133.37B +15.3% +46.2% 30.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$81.13B -1.8% +20.8% 19.5 2.5%
MRNA
Moderna, Inc.
$79.40B +553.0% +4.3% — 8.2%
CSLLY
Csl Ltd
$61.25B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
150
% held
82.3%
Net QoQ
+41.1M sh
Top holder
Artal Group S.A.
Held Float
View
Held by Funds
Fund positions
96
View
Short & Settlement
Short Interest Falling
Shares short
28.8M
Days to cover
13.4d
Change
-697.3K sh
View
Short Volume
Short vol %
47%
As of
Sep 30, 2026
Short Total
View
Fails to Deliver
FTD shares
21.7K
Value
$48.7K
As of
Sep 8, 2026
View
Off-Exchange
Off-exchange %
51.9%
Week of
Aug 24, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$49.8M
Net income (FY)
$-50.3M
EPS diluted
$-0.14
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Sep 14, 2026
This year
14
View
Proposed Sales
Value
$480.0K
Shares
300.0K
Filed
Aug 15, 2024
View
Exempt Offerings
Offering
$59.2M
Filed
Feb 17, 2026
View
Earnings & Events
Earnings Calls
Last call
Sep 14, 2026
View

Performance

5D 20D 120D MTD YTD
LXRX -9.0% -14.4% +6.5% -16.7% +63.0%
SPY -0.7% +0.1% +12.2% -0.6% +11.8%
vs SPY -8.3% -14.5% -5.6% -16.1% +51.2%
Key facts CIK 1062822 CUSIP 528872302 13F (30d) 4 filings 4 filers Visit website Investor relations