PFM Health Sciences, LP

CIK

1442756

Location

SAN FRANCISCO, CA

Portfolio Value

Mid $1,165,442,869

Diversification

Diversified

Filing Date

Global Rank

#1,777 / 8,633 ▲ 80

Top Industry

Biotechnology 42.5%

3Y Alpha vs SPY

-3.9%

Period ended 52 days ago

Filed Aug 14, 2026 · 7d

26 quarters · since Mar 2020

Clone Performance

Aug 2023–Aug 2026 · vs SPY

Hypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.

Cloned portfolio

+62.8%

SPY

+75.1%

Annualised alpha

-2.9%

Max drawdown

−23.6%

Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. Returns use comparable raw closes and exclude dividends; a captured split can shorten the simulated window. It tracks 98% of reported value on average across 13 quarters. Past performance does not predict future results.

Portfolio Concentration

96 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

5.3%

−2.6 pts

Top 5

20.5%

−10.7 pts

Top 10

33.9%

−12.7 pts

HHI

198

Diversified−116

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$1,165,442,869	96

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

23 positions

Ticker	Company	Δ Shares	Shares	Value
EPRX	Eupraxia Pharmaceuticals Inc.	+669,790	1,210,661	$8,002,469
ICLR	Icon PLC	+78,982	136,482	$23,708,288
KOD	Kodiak Sciences Inc.	+78,596	193,315	$7,531,552
CNC	Centene Corp	+73,581	337,067	$21,636,330
NVO	Novo Nordisk A S	+67,835	265,016	$12,704,867
ARWR	Arrowhead Pharmaceuticals, Inc.	+67,388	131,667	$10,732,177
ROIV	Roivant Sciences Ltd.	+60,562	268,008	$9,484,803
ASND	Ascendis Pharma A/S	+58,737	233,171	$62,191,369
COO	Cooper Companies, Inc.	+51,061	220,890	$15,840,021
VERA	Vera Therapeutics, Inc.	+49,422	224,289	$9,624,240
DFTX	Definium Therapeutics, Inc.	+43,703	249,020	$11,713,900
SYK	Stryker Corp	+34,680	56,637	$17,831,593
MMSI	Merit Medical Systems Inc	+34,569	197,038	$13,662,614
UNH	Unitedhealth Group Inc	+30,238	88,276	$36,690,153
WAT	Waters Corp /De/	+20,062	59,825	$22,436,768
OSCR	Oscar Health, Inc.	+19,179	519,016	$14,802,336
CLDX	Celldex Therapeutics, Inc.	+17,794	342,751	$12,753,764
ABVX	Abivax S.A.	+16,600	43,264	$5,765,360
TMO	Thermo Fisher Scientific Inc.	+13,664	28,496	$14,286,754
ILMN	Illumina, Inc.	+6,171	35,040	$6,161,083
PRAX	Praxis Precision Medicines, Inc.	+3,137	38,575	$12,914,524
INBX	Inhibrx Biosciences, Inc.	+2,954	308,385	$29,219,478
RVMD	Revolution Medicines, Inc.	+2,452	143,222	$26,822,616
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
CMPS	COMPASS Pathways plc	−1,119,510	247,589	$3,503,384
CRBU	Caribou Biosciences, Inc.	−603,100	354,687	$624,249
AMRX	Amneal Pharmaceuticals, Inc.	−449,381	480,715	$8,321,176
THC	Tenet Healthcare Corp	−271,995	126,572	$23,679,089
INDV	Indivior Pharmaceuticals, Inc.	−173,458	401,208	$16,461,564
SNDX	Syndax Pharmaceuticals Inc	−126,599	118,422	$2,588,704
MLYS	Mineralys Therapeutics, Inc.	−80,259	62,418	$1,684,037
TNGX	Tango Therapeutics, Inc.	−80,198	326,047	$10,192,229
PEN	Penumbra Inc	−79,558	60,221	$19,014,780
UTHR	UNITED THERAPEUTICS Corp	−67,414	49,991	$27,086,623
ABT	Abbott Laboratories	−58,202	82,230	$7,461,550
ACHC	Acadia Healthcare Company, Inc.	−57,811	524,934	$15,501,301
DNTH	Dianthus Therapeutics, Inc. /DE/	−50,915	121,222	$11,816,720
BTSG	BrightSpring Health Services, Inc.	−45,421	141,914	$9,897,082
AXSM	Axsome Therapeutics, Inc.	−44,708	219,596	$53,750,512
TARS	Tarsus Pharmaceuticals, Inc.	−39,647	40,579	$2,554,042
NTRA	Natera, Inc.	−37,927	22,077	$5,992,801
CGON	CG Oncology, Inc.	−37,639	128,286	$9,114,720
RYTM	Rhythm Pharmaceuticals, Inc.	−35,071	101,550	$11,275,096
CGEM	Cullinan Therapeutics, Inc.	−34,964	192,442	$3,504,368
GPCR	Structure Therapeutics Inc.	−34,833	91,550	$4,913,488
LLY	ELI LILLY & Co	−26,504	39,258	$47,087,226
BLTE	Belite Bio, Inc	−24,629	34,803	$5,359,139
HSIC	Henry Schein Inc	−18,691	134,423	$11,227,008
JAZZ	Jazz Pharmaceuticals plc	−17,376	160,768	$38,740,264
No positions match the current search.

New Positions

Positions the filer opened this quarter

25 positions

Ticker	Company	Shares	Value
HUM	Humana Inc	94,375	$37,487,637
MTD	Mettler Toledo International Inc/	13,344	$17,047,093
MRK	Merck & Co., Inc.	127,118	$16,334,663
CYTK	Cytokinetics Inc	191,686	$16,329,730
LNTH	Lantheus Holdings, Inc.	146,403	$16,241,948
CVS	CVS HEALTH Corp	137,457	$14,219,926
GILD	Gilead Sciences, Inc.	90,858	$11,478,999
TFX	Teleflex Inc	79,708	$10,103,786
COR	Cencora, Inc.	35,485	$10,041,545
IRTC	iRhythm Holdings, Inc.	65,196	$7,755,064
WST	West Pharmaceutical Services Inc	20,733	$7,443,147
TAK	Takeda Pharmaceutical Co Ltd	444,173	$7,120,093
HNGE	Hinge Health, Inc.	82,860	$6,877,380
ARQT	Arcutis Biotherapeutics, Inc.	242,069	$6,347,049
IART	Integra Lifesciences Holdings Corp	348,746	$6,263,478
MGTX	MeiraGTx Holdings plc	455,286	$6,150,913
OCS	Oculis Holding AG	436,042	$6,047,902
GH	Guardant Health, Inc.	36,701	$5,506,251
CELC	Celcuity Inc.	52,155	$5,456,456
RCUS	Arcus Biosciences, Inc.	152,129	$4,690,137
CRL	Charles River Laboratories International, Inc.	18,747	$4,251,632
ELAN	Elanco Animal Health Inc	172,489	$4,244,954
BIO	Bio-Rad Laboratories, Inc.	13,995	$4,109,071
SYRE	Spyre Therapeutics, Inc.	46,217	$4,103,145
MIRM	Mirum Pharmaceuticals, Inc.	31,536	$3,691,919
No positions match the current search.

Sold Out

Positions the filer fully exited

12 positions

Ticker	Company	Shares	Value
GKOS	GLAUKOS Corp	215,685	$23,220,647
NEO	Neogenomics Inc	1,784,552	$13,241,375
DXCM	Dexcom Inc	149,734	$9,403,295
BLLN	BillionToOne, Inc.	88,069	$6,952,166
CAH	Cardinal Health Inc	31,941	$6,749,452
ALHC	Alignment Healthcare, Inc.	359,826	$6,340,134
PSNL	Personalis, Inc.	870,097	$5,542,517
MDLN	Medline Inc.	86,777	$3,861,576
GMED	Globus Medical Inc	16,923	$1,458,085
SLNO	Soleno Therapeutics Inc	248,180	$0
TERN	Terns Pharmaceuticals, Inc.	172,962	$0
CNTA	Centessa Pharmaceuticals plc	528,224	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

96 tracked positions · $1,165,442,869 total · filing declares 98 positions · $1,165,441,614 · as of Jun 30, 2026

All sectors Healthcare

Showing 1–50 of 96 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
ASND	Ascendis Pharma A/S Healthcare	Added	233,171	+58,737	$62,191,369	+55.9%	5.34%
AXSM	Axsome Therapeutics, Inc. Healthcare	Reduced	219,596	-44,708	$53,750,512	+20.3%	4.61%
LLY	ELI LILLY & Co Healthcare	Reduced	39,258	-26,504	$47,087,226	−22.2%	4.04%
JAZZ	Jazz Pharmaceuticals plc Healthcare	Reduced	160,768	-17,376	$38,740,264	+15.0%	3.32%
HUM	Humana Inc Healthcare	NEW	94,375	NEW	$37,487,637	NEW	3.22%
UNH	Unitedhealth Group Inc Healthcare	Added	88,276	+30,238	$36,690,153	+133.6%	3.15%
NBIX	Neurocrine Biosciences Inc Healthcare	Reduced	213,407	-2,271	$35,967,615	+26.6%	3.09%
INBX	Inhibrx Biosciences, Inc. Healthcare	Added	308,385	+2,954	$29,219,478	+42.3%	2.51%
UTHR	UNITED THERAPEUTICS Corp Healthcare	Reduced	49,991	-67,414	$27,086,623	−61.1%	2.32%
RVMD	Revolution Medicines, Inc. Healthcare	Added	143,222	+2,452	$26,822,616	+95.9%	2.30%
ICLR	Icon PLC Healthcare	Added	136,482	+78,982	$23,708,288	+272.6%	2.03%
THC	Tenet Healthcare Corp Healthcare	Reduced	126,572	-271,995	$23,679,089	−68.5%	2.03%
EW	Edwards Lifesciences Corp Healthcare	Reduced	250,453	-4,057	$22,655,978	+11.2%	1.94%
WAT	Waters Corp /De/ Healthcare	Added	59,825	+20,062	$22,436,768	+89.5%	1.93%
CNC	Centene Corp PUT + SHARES Healthcare	Added	337,067	+73,581	$21,636,330	+150.8%	1.86%
PEN	Penumbra Inc Healthcare	Reduced	60,221	-79,558	$19,014,780	−58.6%	1.63%
BBIO	BridgeBio Pharma, Inc. Healthcare	Reduced	253,358	-4,389	$18,870,103	−1.4%	1.62%
SYK	Stryker Corp Healthcare	Added	56,637	+34,680	$17,831,593	+147.2%	1.53%
MTD	Mettler Toledo International Inc/ Healthcare	NEW	13,344	NEW	$17,047,093	NEW	1.46%
INDV	Indivior Pharmaceuticals, Inc. Healthcare	Reduced	401,208	-173,458	$16,461,564	−6.0%	1.41%
MRK	Merck & Co., Inc. Healthcare	NEW	127,118	NEW	$16,334,663	NEW	1.40%
CYTK	Cytokinetics Inc Healthcare	NEW	191,686	NEW	$16,329,730	NEW	1.40%
LNTH	Lantheus Holdings, Inc. Healthcare	NEW	146,403	NEW	$16,241,948	NEW	1.39%
COO	Cooper Companies, Inc. Healthcare	Added	220,890	+51,061	$15,840,021	+30.4%	1.36%
MDGL	Madrigal Pharmaceuticals, Inc. Healthcare	Reduced	29,313	-4,833	$15,739,615	−11.9%	1.35%
ACHC	Acadia Healthcare Company, Inc. Healthcare	Reduced	524,934	-57,811	$15,501,301	+13.7%	1.33%
ORKA	Oruka Therapeutics, Inc. Healthcare	Reduced	158,825	-15,227	$15,115,375	+77.1%	1.30%
OSCR	Oscar Health, Inc. Healthcare	Added	519,016	+19,179	$14,802,336	+158.2%	1.27%
TMO	Thermo Fisher Scientific Inc. Healthcare	Added	28,496	+13,664	$14,286,754	+96.0%	1.23%
CVS	CVS HEALTH Corp Healthcare	NEW	137,457	NEW	$14,219,926	NEW	1.22%
MMSI	Merit Medical Systems Inc Healthcare	Added	197,038	+34,569	$13,662,614	+22.0%	1.17%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Added	38,575	+3,137	$12,914,524	+13.1%	1.11%
CLDX	Celldex Therapeutics, Inc. Healthcare	Added	342,751	+17,794	$12,753,764	+23.7%	1.09%
NVO	Novo Nordisk A S Healthcare	Added	265,016	+67,835	$12,704,867	+75.3%	1.09%
ITGR	Integer Holdings Corp Healthcare	Reduced	126,669	-8,412	$11,837,218	−0.4%	1.02%
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	Reduced	121,222	-50,915	$11,816,720	−18.2%	1.01%
DFTX	Definium Therapeutics, Inc. Healthcare	Added	249,020	+43,703	$11,713,900	+201.9%	1.01%
GILD	Gilead Sciences, Inc. Healthcare	NEW	90,858	NEW	$11,478,999	NEW	0.98%
RYTM	Rhythm Pharmaceuticals, Inc. Healthcare	Reduced	101,550	-35,071	$11,275,096	−5.1%	0.97%
HSIC	Henry Schein Inc Healthcare	Reduced	134,423	-18,691	$11,227,008	−0.5%	0.96%
ARWR	Arrowhead Pharmaceuticals, Inc. Healthcare	Added	131,667	+67,388	$10,732,177	+166.3%	0.92%
TNGX	Tango Therapeutics, Inc. Healthcare	Reduced	326,047	-80,198	$10,192,229	+19.9%	0.87%
TFX	Teleflex Inc Healthcare	NEW	79,708	NEW	$10,103,786	NEW	0.87%
COR	Cencora, Inc. CALL + SHARES Healthcare	NEW	35,485	NEW	$10,041,545	NEW	0.86%
VKTX	Viking Therapeutics, Inc. Healthcare	Reduced	255,330	-7,776	$9,960,423	+16.3%	0.85%
BTSG	BrightSpring Health Services, Inc. Healthcare	Reduced	141,914	-45,421	$9,897,082	+24.0%	0.85%
VERA	Vera Therapeutics, Inc. Healthcare	Added	224,289	+49,422	$9,624,240	+36.8%	0.83%
ROIV	Roivant Sciences Ltd. Healthcare	Added	268,008	+60,562	$9,484,803	+65.1%	0.81%
CGON	CG Oncology, Inc. Healthcare	Reduced	128,286	-37,639	$9,114,720	−18.8%	0.78%
AMRX	Amneal Pharmaceuticals, Inc. Healthcare	Reduced	480,715	-449,381	$8,321,176	−28.0%	0.71%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.