Tetragon Partners GP Ltd

CIK

1515070

Location

GRAND CAYMAN, E9

Portfolio Value

Small $635,255,072

Diversification

Highly concentrated

Reports for

Tetragon Partners L.P. Tetragon Partners UK LLP Tetragon Partners US LP

Filing Date

Global Rank

#3,318 / 8,795 ▼ 39 · as of Jun 2026

Top Industry

Software - Infrastructure 53.0%

3Y Alpha vs SPY

-10.2%

Period ended 3 months ago

Filed Aug 13, 2026 · 54d

26 quarters · since Mar 2020

Clone Performance

Build a hypothetical price-return history from this filer's public 13F holdings.

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Portfolio Concentration

36 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

53.0%

−1.7 pts

Top 5

65.1%

−7.3 pts

Top 10

74.2%

−8.8 pts

HHI

2,898

Highly concentrated−225

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Technology	61.1%	$387,938,145	6
Healthcare	32.5%	$206,616,099	28
Energy	5.4%	$34,035,829	1
Communication Services	1.0%	$6,664,999	1

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

17 positions

Ticker	Company	Δ Shares	Shares	Value
PATH	UiPath, Inc.	+5,742,372	30,950,000	$336,426,499
SLN	Silence Therapeutics plc	+434,095	1,064,256	$11,685,530
RLAY	Relay Therapeutics, Inc.	+388,768	570,311	$10,670,518
KPTI	Karyopharm Therapeutics Inc.	+147,316	250,300	$2,445,431
DYN	Dyne Therapeutics, Inc.	+98,525	356,657	$7,921,351
AGIO	Agios Pharmaceuticals, Inc.	+90,740	255,579	$9,484,536
DFTX	Definium Therapeutics, Inc.	+86,996	286,990	$13,500,009
HRMY	Harmony Biosciences Holdings, Inc.	+81,696	201,036	$7,319,720
PHVS	Pharvaris N.V.	+74,016	295,627	$10,222,781
RARE	Ultragenyx Pharmaceutical Inc.	+60,527	100,000	$3,339,000
MBX	MBX Biosciences, Inc.	+58,063	203,543	$11,235,573
IONS	Ionis Pharmaceuticals Inc	+55,409	97,173	$7,704,847
IMVT	Immunovant, Inc.	+37,427	255,934	$9,861,137
ALKS	Alkermes plc.	+30,188	189,979	$9,954,899
ACAD	Acadia Pharmaceuticals Inc	+23,255	167,875	$4,247,237
TECX	Tectonic Therapeutic, Inc.	+8,928	46,516	$1,599,220
ARWR	Arrowhead Pharmaceuticals, Inc.	+3,286	130,484	$10,635,750
No positions match the current search.

Trimmed

Positions the filer reduced

6 positions

Ticker	Company	Δ Shares	Shares	Value
WBD	Warner Bros. Discovery, Inc.	−673,725	250,000	$6,664,999
ANNX	Annexon, Inc.	−50,000	1,242,455	$7,094,418
CLDX	Celldex Therapeutics, Inc.	−21,875	290,441	$10,807,309
AXSM	Axsome Therapeutics, Inc.	−20,059	35,000	$8,566,950
NKTR	Nektar Therapeutics	−16,041	86,996	$6,073,190
AMLX	Amylyx Pharmaceuticals, Inc.	−11,451	306,426	$5,503,410
No positions match the current search.

New Positions

Positions the filer opened this quarter

6 positions

Ticker	Company	Shares	Value
ALKT	Alkami Technology, Inc.	600,284	$10,877,146
CELC	Celcuity Inc.	64,110	$6,707,188
CUE	Cue Biopharma, Inc.	93,819	$2,960,927
ACRS	Aclaris Therapeutics, Inc.	400,000	$2,116,000
GLUE	Monte Rosa Therapeutics, Inc.	56,052	$1,356,458
TENX	Tenax Therapeutics, Inc.	75,100	$1,092,705
No positions match the current search.

Sold Out

Positions the filer fully exited

4 positions

Ticker	Company	Shares	Value
PRAX	Praxis Precision Medicines, Inc.	15,952	$5,139,574
MPLT	MapLight Therapeutics, Inc.	112,115	$2,279,297
AARD	Aardvark Therapeutics, Inc.	316,621	$1,193,661
—		102,125	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

36 tracked positions · $635,255,072 total · filing declares 43 positions · $635,063,221 · as of Jun 30, 2026

All sectors Communication Services Energy Healthcare Technology

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
PATH	UiPath, Inc. Technology	Added	30,950,000	+5,742,372	$336,426,499	+20.2%	52.96%
KGEI	Kolibri Global Energy Inc. Energy	Held	6,834,504	0	$34,035,829	−9.3%	5.36%
AUTL	Autolus Therapeutics plc Healthcare	Held	9,500,000	0	$15,200,000	+15.9%	2.39%
LYFT	Lyft, Inc. Technology	Held	1,000,000	0	$14,610,000	+9.8%	2.30%
DFTX	Definium Therapeutics, Inc. Healthcare	Added	286,990	+86,996	$13,500,009	+257.2%	2.13%
WK	Workiva Inc Technology	Held	250,000	0	$12,127,500	−18.6%	1.91%
SLN	Silence Therapeutics plc CALL + SHARES Healthcare	Added	1,064,256	+434,095	$11,685,530	+251.9%	1.84%
CXM	Sprinklr, Inc. Technology	Held	2,200,000	0	$11,352,000	−14.0%	1.79%
MBX	MBX Biosciences, Inc. Healthcare	Added	203,543	+58,063	$11,235,573	+158.7%	1.77%
ALKT	Alkami Technology, Inc. Technology	NEW	600,284	NEW	$10,877,146	NEW	1.71%
CLDX	Celldex Therapeutics, Inc. Healthcare	Reduced	290,441	-21,875	$10,807,309	+9.1%	1.70%
RLAY	Relay Therapeutics, Inc. Healthcare	Added	570,311	+388,768	$10,670,518	+490.7%	1.68%
ARWR	Arrowhead Pharmaceuticals, Inc. Healthcare	Added	130,484	+3,286	$10,635,750	+33.4%	1.67%
PHVS	Pharvaris N.V. Healthcare	Added	295,627	+74,016	$10,222,781	+63.3%	1.61%
ALKS	Alkermes plc. Healthcare	Added	189,979	+30,188	$9,954,899	+76.2%	1.57%
IMVT	Immunovant, Inc. Healthcare	Added	255,934	+37,427	$9,861,137	+81.7%	1.55%
AGIO	Agios Pharmaceuticals, Inc. CALL + SHARES Healthcare	Added	255,579	+90,740	$9,484,536	+70.1%	1.49%
AXSM	Axsome Therapeutics, Inc. CALL Healthcare	Reduced	35,000	-20,059	$8,566,950	−7.9%	1.35%
DYN	Dyne Therapeutics, Inc. Healthcare	Added	356,657	+98,525	$7,921,351	+69.3%	1.25%
IONS	Ionis Pharmaceuticals Inc Healthcare	Added	97,173	+55,409	$7,704,847	+145.7%	1.21%
HRMY	Harmony Biosciences Holdings, Inc. Healthcare	Added	201,036	+81,696	$7,319,720	+119.0%	1.15%
KRYS	Krystal Biotech, Inc. Healthcare	Held	19,668	0	$7,310,005	+43.9%	1.15%
ANNX	Annexon, Inc. Healthcare	Reduced	1,242,455	-50,000	$7,094,418	−0.9%	1.12%
CELC	Celcuity Inc. Healthcare	NEW	64,110	NEW	$6,707,188	NEW	1.06%
WBD	Warner Bros. Discovery, Inc. Communication Services	Reduced	250,000	-673,725	$6,664,999	−73.7%	1.05%
NKTR	Nektar Therapeutics Healthcare	Reduced	86,996	-16,041	$6,073,190	−18.1%	0.96%
AMLX	Amylyx Pharmaceuticals, Inc. CALL + SHARES Healthcare	Reduced	306,426	-11,451	$5,503,410	+24.6%	0.87%
ACAD	Acadia Pharmaceuticals Inc Healthcare	Added	167,875	+23,255	$4,247,237	+31.9%	0.67%
RARE	Ultragenyx Pharmaceutical Inc. CALL Healthcare	Added	100,000	+60,527	$3,339,000	+303.8%	0.53%
CUE	Cue Biopharma, Inc. Healthcare	NEW	93,819	NEW	$2,960,927	NEW	0.47%
SNOW	Snowflake Inc. Technology	Held	10,000	0	$2,545,000	+68.7%	0.40%
KPTI	Karyopharm Therapeutics Inc. CALL Healthcare	Added	250,300	+147,316	$2,445,431	+326.3%	0.38%
ACRS	Aclaris Therapeutics, Inc. Healthcare	NEW	400,000	NEW	$2,116,000	NEW	0.33%
TECX	Tectonic Therapeutic, Inc. Healthcare	Added	46,516	+8,928	$1,599,220	+37.6%	0.25%
GLUE	Monte Rosa Therapeutics, Inc. Healthcare	NEW	56,052	NEW	$1,356,458	NEW	0.21%
TENX	Tenax Therapeutics, Inc. CALL Healthcare	NEW	75,100	NEW	$1,092,705	NEW	0.17%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.