Tetragon Partners GP Ltd
CIK
1515070
Location
GRAND CAYMAN, E9
Portfolio Value
Small
$635,255,072
Diversification
Highly concentrated
Reports for
Tetragon Partners L.P.
Tetragon Partners UK LLP
Tetragon Partners US LP
Filing Date
Global Rank
#2,465
/ 8,645
▲ 196
Top Industry
Software - Infrastructure
53.0%
3Y Alpha vs SPY
-3.6%
Period ended 52 days ago
Filed Aug 13, 2026 · 8d
26 quarters · since Mar 2020
Clone Performance
Aug 2023–Aug 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+59.7%
SPY
+73.6%
Annualised alpha
-3.3%
Max drawdown
−40.2%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. Returns use comparable raw closes and exclude dividends; a captured split can shorten the simulated window. It tracks 99% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
36 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
53.0%
−1.7 pts
Top 5
65.1%
−7.3 pts
Top 10
74.2%
−8.8 pts
HHI
2,898
Highly concentrated−225
Portfolio Trend
26 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Technology | 61.1% | $387,938,145 |
| Healthcare | 32.5% | $206,616,099 |
| Energy | 5.4% | $34,035,829 |
| Communication Services | 1.0% | $6,664,999 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
17 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| PATH | UiPath, Inc. | +5,742,372 | 30,950,000 | $336,426,499 | |
| SLN | Silence Therapeutics plc | +434,095 | 1,064,256 | $11,685,530 | |
| RLAY | Relay Therapeutics, Inc. | +388,768 | 570,311 | $10,670,518 | |
| KPTI | Karyopharm Therapeutics Inc. | +147,316 | 250,300 | $2,445,431 | |
| DYN | Dyne Therapeutics, Inc. | +98,525 | 356,657 | $7,921,351 | |
| AGIO | Agios Pharmaceuticals, Inc. | +90,740 | 255,579 | $9,484,536 | |
| DFTX | Definium Therapeutics, Inc. | +86,996 | 286,990 | $13,500,009 | |
| HRMY | Harmony Biosciences Holdings, Inc. | +81,696 | 201,036 | $7,319,720 | |
| PHVS | Pharvaris N.V. | +74,016 | 295,627 | $10,222,781 | |
| RARE | Ultragenyx Pharmaceutical Inc. | +60,527 | 100,000 | $3,339,000 | |
| MBX | MBX Biosciences, Inc. | +58,063 | 203,543 | $11,235,573 | |
| IONS | Ionis Pharmaceuticals Inc | +55,409 | 97,173 | $7,704,847 | |
| IMVT | Immunovant, Inc. | +37,427 | 255,934 | $9,861,137 | |
| ALKS | Alkermes plc. | +30,188 | 189,979 | $9,954,899 | |
| ACAD | Acadia Pharmaceuticals Inc | +23,255 | 167,875 | $4,247,237 | |
| TECX | Tectonic Therapeutic, Inc. | +8,928 | 46,516 | $1,599,220 | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | +3,286 | 130,484 | $10,635,750 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
6 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| WBD | Warner Bros. Discovery, Inc. | −673,725 | 250,000 | $6,664,999 | |
| ANNX | Annexon, Inc. | −50,000 | 1,242,455 | $7,094,418 | |
| CLDX | Celldex Therapeutics, Inc. | −21,875 | 290,441 | $10,807,309 | |
| AXSM | Axsome Therapeutics, Inc. | −20,059 | 35,000 | $8,566,950 | |
| NKTR | Nektar Therapeutics | −16,041 | 86,996 | $6,073,190 | |
| AMLX | Amylyx Pharmaceuticals, Inc. | −11,451 | 306,426 | $5,503,410 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
6 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| ALKT | Alkami Technology, Inc. | 600,284 | $10,877,146 | |
| CELC | Celcuity Inc. | 64,110 | $6,707,188 | |
| CUE | Cue Biopharma, Inc. | 93,819 | $2,960,927 | |
| ACRS | Aclaris Therapeutics, Inc. | 400,000 | $2,116,000 | |
| GLUE | Monte Rosa Therapeutics, Inc. | 56,052 | $1,356,458 | |
| TENX | Tenax Therapeutics, Inc. | 75,100 | $1,092,705 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
4 positions
36 tracked positions ·
$635,255,072 total
· filing declares
43 positions · $635,063,221
· as of Jun 30, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| PATH |
UiPath, Inc.
Technology
|
Added | 30,950,000 | $336,426,499 | 52.96% | |
| KGEI |
Kolibri Global Energy Inc.
Energy
|
Held | 6,834,504 | $34,035,829 | 5.36% | |
| AUTL |
Autolus Therapeutics plc
Healthcare
|
Held | 9,500,000 | $15,200,000 | 2.39% | |
| LYFT |
Lyft, Inc.
Technology
|
Held | 1,000,000 | $14,610,000 | 2.30% | |
| DFTX |
Definium Therapeutics, Inc.
Healthcare
|
Added | 286,990 | $13,500,009 | 2.13% | |
| WK |
Workiva Inc
Technology
|
Held | 250,000 | $12,127,500 | 1.91% | |
| SLN |
Silence Therapeutics plc
CALL
+ SHARES
Healthcare
|
Added | 1,064,256 | $11,685,530 | 1.84% | |
| CXM |
Sprinklr, Inc.
Technology
|
Held | 2,200,000 | $11,352,000 | 1.79% | |
| MBX |
MBX Biosciences, Inc.
Healthcare
|
Added | 203,543 | $11,235,573 | 1.77% | |
| ALKT |
Alkami Technology, Inc.
Technology
|
NEW | 600,284 | $10,877,146 | 1.71% | |
| CLDX |
Celldex Therapeutics, Inc.
Healthcare
|
Reduced | 290,441 | $10,807,309 | 1.70% | |
| RLAY |
Relay Therapeutics, Inc.
Healthcare
|
Added | 570,311 | $10,670,518 | 1.68% | |
| ARWR |
Arrowhead Pharmaceuticals, Inc.
Healthcare
|
Added | 130,484 | $10,635,750 | 1.67% | |
| PHVS |
Pharvaris N.V.
Healthcare
|
Added | 295,627 | $10,222,781 | 1.61% | |
| ALKS |
Alkermes plc.
Healthcare
|
Added | 189,979 | $9,954,899 | 1.57% | |
| IMVT |
Immunovant, Inc.
Healthcare
|
Added | 255,934 | $9,861,137 | 1.55% | |
| AGIO |
Agios Pharmaceuticals, Inc.
CALL
+ SHARES
Healthcare
|
Added | 255,579 | $9,484,536 | 1.49% | |
| AXSM |
Axsome Therapeutics, Inc.
CALL
Healthcare
|
Reduced | 35,000 | $8,566,950 | 1.35% | |
| DYN |
Dyne Therapeutics, Inc.
Healthcare
|
Added | 356,657 | $7,921,351 | 1.25% | |
| IONS |
Ionis Pharmaceuticals Inc
Healthcare
|
Added | 97,173 | $7,704,847 | 1.21% | |
| HRMY |
Harmony Biosciences Holdings, Inc.
Healthcare
|
Added | 201,036 | $7,319,720 | 1.15% | |
| KRYS |
Krystal Biotech, Inc.
Healthcare
|
Held | 19,668 | $7,310,005 | 1.15% | |
| ANNX |
Annexon, Inc.
Healthcare
|
Reduced | 1,242,455 | $7,094,418 | 1.12% | |
| CELC |
Celcuity Inc.
Healthcare
|
NEW | 64,110 | $6,707,188 | 1.06% | |
| WBD |
Warner Bros. Discovery, Inc.
Communication Services
|
Reduced | 250,000 | $6,664,999 | 1.05% | |
| NKTR |
Nektar Therapeutics
Healthcare
|
Reduced | 86,996 | $6,073,190 | 0.96% | |
| AMLX |
Amylyx Pharmaceuticals, Inc.
CALL
+ SHARES
Healthcare
|
Reduced | 306,426 | $5,503,410 | 0.87% | |
| ACAD |
Acadia Pharmaceuticals Inc
Healthcare
|
Added | 167,875 | $4,247,237 | 0.67% | |
| RARE |
Ultragenyx Pharmaceutical Inc.
CALL
Healthcare
|
Added | 100,000 | $3,339,000 | 0.53% | |
| CUE |
Cue Biopharma, Inc.
Healthcare
|
NEW | 93,819 | $2,960,927 | 0.47% | |
| SNOW |
Snowflake Inc.
Technology
|
Held | 10,000 | $2,545,000 | 0.40% | |
| KPTI |
Karyopharm Therapeutics Inc.
CALL
Healthcare
|
Added | 250,300 | $2,445,431 | 0.38% | |
| ACRS |
Aclaris Therapeutics, Inc.
Healthcare
|
NEW | 400,000 | $2,116,000 | 0.33% | |
| TECX |
Tectonic Therapeutic, Inc.
Healthcare
|
Added | 46,516 | $1,599,220 | 0.25% | |
| GLUE |
Monte Rosa Therapeutics, Inc.
Healthcare
|
NEW | 56,052 | $1,356,458 | 0.21% | |
| TENX |
Tenax Therapeutics, Inc.
CALL
Healthcare
|
NEW | 75,100 | $1,092,705 | 0.17% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.