BMEA · Biomea Fusion, Inc. · Holdings
Substantial doubt about the company's ability to continue as a going concern.
“In connection with the preparation of this Quarterly Report on Form 10-Q for the period ended June 30, 2026, our management has concluded that there is substantial doubt as to whether we can continue as a going concern for the twelve months following the issuance of this Quarterly Report on Form 10-Q. Our ability to continue as a going concern is dependent upon raising capital to maintain current operations and continue research and development efforts. We plan to raise additional capital to fund our operations through public or private equity offerings, debt financings, and/or potential collaborations and license arrangement or other sources. There is no assurance, however, that any additional financing or any revenue-generating collaboration will be available when needed or that we will be able to obtain financing or enter into a collaboration on terms acceptable to us. Based on our current operating plan, we will not be able to continue as a going concern over the next twelve months unless we raise additional capital by other means. These factors raise substantial doubt about our ability to continue as a going concern.”View the 10-Q filed Aug 5, 2026
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 62 13F filersWho Holds BMEA
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 61 filers, like-for-like change +3.7%; actively managed books +2.1%; index-like books +9.6%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 35.7% | 25 | +0.6% |
| Exempt adviser | 9.0% | 3 | +58.1% |
| Adviser | 0.0% | 1 | +7.4% |
| Bank | 3.5% | 9 | -13.1% |
| Non-US | 0.0% | 2 | +0.2% |
| Holding company | 39.6% | 5 | +1.2% |
| Broker-dealer | 0.0% | 0 | -100.0% |
| Insurer | 0.0% | 0 | — |
| Benefit plan | 0.0% | 0 | — |
| Unknown | 12.2% | 16 | +2.2% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 21.6% | 9 | +9.6% |
| Systematic-like | 14.3% | 12 | +11.9% |
| Concentrated | 9.3% | 7 | -2.1% |
| Diversified active | 54.8% | 33 | +0.6% |
| Not measured | 0.0% | 0 | — |
| Unknown | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 56.4% | 29 | +2.8% |
| Medium turnover | 8.5% | 9 | -11.8% |
| High turnover | 19.5% | 16 | +8.7% |
| Unknown | 15.6% | 7 | +11.4% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 19.8% | 12 | +9.5% |
| Medium horizon | 4.3% | 7 | +6.3% |
| Long horizon | 65.9% | 36 | -2.6% |
| Unknown | 10.1% | 6 | +49.0% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 9.9% | 11 | -1.0% |
| $1B to $10B | 7.3% | 13 | +16.7% |
| $10B to $100B | 18.3% | 13 | +20.1% |
| $100B or more | 64.5% | 24 | -0.7% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 3.9% | 12 | +18.2% |
| Pooled investment vehicles | 17.4% | 10 | -3.2% |
| Registered funds and BDCs | 14.3% | 3 | +11.3% |
| Governments and sovereign funds | 0.0% | 0 | -100.0% |
| Other investment advisers | 0.0% | 0 | -100.0% |
| Diversified | 0.0% | 0 | -100.0% |
| Pension and profit sharing plans | 0.0% | 0 | — |
| Insurance companies | 0.0% | 0 | — |
| Unknown | 64.3% | 36 | +5.5% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 17.3% | 10 | +9.5% |
| Private equity funds | 10.5% | 4 | -2.2% |
| Real estate funds | 1.1% | 2 | +223.3% |
| Other private funds | 0.3% | 2 | -23.5% |
| Private funds, type not stated | 0.8% | 1 | 0.0% |
| No private funds | 14.5% | 9 | +12.0% |
| Mixed private funds | 0.0% | 0 | — |
| Securitized asset funds | 0.0% | 0 | — |
| Unknown | 55.4% | 33 | +0.1% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 83.3% | 47 | 0.0% |
| Outside the US | 16.7% | 14 | +26.6% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Excluded 3 holders with no observed 2026-03-31 13F.
Conviction and Crowding
61 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 84.4% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shareholder Targets
13F filers that own its peers but not BMEA, quarter ended Sep 30, 2025Found through its holder-overlap peers: CABA, BBIO. 349 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | VIKING GLOBAL INVESTORS LP Registered adviser, Diversified active | $829,889,477 1 held | BBIO |
| 2 | Kohlberg Kravis Roberts & Co. L.P. Registered adviser, Concentrated | $688,774,833 1 held | BBIO |
| 3 | JANUS HENDERSON GROUP PLC Adviser, Diversified active | $454,011,642 1 held | BBIO |
| 4 | FARALLON CAPITAL MANAGEMENT LLC Registered adviser, Diversified active | $425,492,480 1 held | BBIO |
| 5 | Invesco Ltd. Adviser, Diversified active | $204,341,793 2 held | BBIO, CABA |
| 6 | Frazier Life Sciences Management, L.P. Registered adviser, Concentrated | $199,733,036 1 held | BBIO |
| 7 | ALLIANCEBERNSTEIN L.P. Registered adviser, Diversified active | $120,953,457 1 held | BBIO |
| 8 | D. E. Shaw & Co., Inc. Unknown, Systematic-like | $117,008,458 1 held | BBIO |
| 9 | Capital Research Global Investors Adviser, Diversified active | $100,406,564 1 held | BBIO |
| 10 | MACQUARIE GROUP LTD Unknown, Diversified active | $100,405,006 1 held | BBIO |
Fund Ownership of BMEA by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 5.05% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 0.93% | 672,476 |
| Index ETFs | 4.12% | 2,987,242 |
| Active ETFs | 0.00% | 0 |
| Active funds | 6.95% | 5,035,735 |
| Unclassified | 0.00% | 0 |
| All registered funds | 12.00% | 8,695,453 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Mega FMR LLC Holding company | $12,957,970 | 33.67% | 8,814,946 | Shares | 2026-08-13 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $4,159,992 | 10.81% | 2,829,927 | Shares | 2026-08-13 | |
| Large MARSHALL WACE, LLP Exempt adviser | $3,013,208 | 7.83% | 2,049,802 | Shares | 2026-08-13 | |
| Small Aisling Capital Management LP Registered adviser | $3,011,672 | 7.83% | 2,048,757 | Shares | 2026-08-13 | |
| Large RENAISSANCE TECHNOLOGIES LLC Registered adviser | $2,139,546 | 5.56% | 1,455,474 | Shares | 2026-08-13 | |
| Mid FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1,063,068 | 2.76% | 723,176 | Shares | 2026-07-23 | |
| Mega BlackRock, Inc. Holding company | $1,051,703 | 2.73% | 715,445 | Shares | 2026-08-07 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $1,042,014 | 2.71% | 708,854 | Shares | 2026-08-12 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $900,720 | 2.34% | 612,735 | Shares | 2026-08-14 | |
| Large Mariner, LLC Registered adviser | $874,247 | 2.27% | 594,726 | Shares | 2026-08-13 | |
| Mega JANE STREET GROUP, LLC | $673,684 | 1.75% | 458,289 | Shares | 2026-08-14 | |
| Mega UBS Group AG Bank | $653,749 | 1.70% | 444,728 | Shares | 2026-08-13 | |
| Mid XTX Topco Ltd | $598,112 | 1.55% | 406,879 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $585,795 | 1.52% | 398,500 | Call | 2026-08-14 | |
| Mega TWO SIGMA INVESTMENTS, LP Registered adviser | $565,154 | 1.47% | 384,459 | Shares | 2026-08-14 | |
| Mega MORGAN STANLEY Holding company | $539,519 | 1.40% | 367,021 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $497,367 | 1.29% | 338,345 | Shares | 2026-08-13 | |
| Large MAI Capital Management Registered adviser | $424,977 | 1.10% | 289,100 | Shares | 2026-08-14 | |
| Mega STATE STREET CORP Bank | $378,253 | 0.98% | 257,315 | Shares | 2026-09-22 | |
| Small SUPERSTRING CAPITAL MANAGEMENT LP | $367,500 | 0.96% | 250,000 | Shares | 2026-08-14 | |
| Mid GSA CAPITAL PARTNERS LLP Registered adviser | $317,549 | 0.83% | 216,020 | Shares | 2026-08-06 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $317,226 | 0.82% | 215,800 | Put | 2026-08-14 | |
| Large LMR Partners LLP Exempt adviser | $294,000 | 0.76% | 200,000 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $262,101 | 0.68% | 178,300 | Call | 2026-09-02 | |
| Mega NORTHERN TRUST CORP Bank | $188,933 | 0.49% | 128,526 | Shares | 2026-08-13 | |
| Mega JANE STREET GROUP, LLC | $180,810 | 0.47% | 123,000 | Call | 2026-08-14 | |
| Small Headlands Technologies LLC | $163,683 | 0.43% | 111,349 | Shares | 2026-08-13 | |
| Large Marex Group plc | $147,000 | 0.38% | 100,000 | Shares | 2026-08-14 | |
| Mega GOLDMAN SACHS GROUP INC Holding company | $137,822 | 0.36% | 93,757 | Shares | 2026-08-14 | |
| Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC Registered adviser | $124,362 | 0.32% | 84,600 | Shares | 2026-08-14 | |
| Large Jain Global LLC Registered adviser | $111,276 | 0.29% | 75,698 | Shares | 2026-08-14 | |
| Small GRIFFIN ASSET MANAGEMENT, INC. Registered adviser | $87,906 | 0.23% | 59,800 | Shares | 2026-07-23 | |
| Mid Graham Capital Management, L.P. Registered adviser | $78,578 | 0.20% | 53,455 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $66,026 | 0.17% | 44,916 | Shares | 2026-09-02 | |
| Mid ADAR1 Capital Management, LLC Registered adviser | $63,827 | 0.17% | 43,420 | Shares | 2026-08-14 | |
| Large Rathbones Group PLC | $54,390 | 0.14% | 37,000 | Shares | 2026-07-23 | |
| Mega Vanguard Global Advisers, LLC Registered adviser | $50,900 | 0.13% | 34,626 | Shares | 2026-08-13 | |
| Large Point72 Asset Management, L.P. Registered adviser | $48,204 | 0.13% | 32,792 | Shares | 2026-08-14 | |
| Mega PNC FINANCIAL SERVICES GROUP, INC. Bank | $35,280 | 0.09% | 24,000 | Shares | 2026-08-07 | |
| Mega Bank of New York Mellon Corp Bank | $23,182 | 0.06% | 15,771 | Shares | 2026-08-06 | |
| Mid CFS Investment Advisory Services, LLC | $21,037 | 0.05% | 15,818 | Shares | 2026-10-19 | |
| Small BIRCH FINANCIAL GROUP, LLC | $20,580 | 0.05% | 14,000 | Shares | 2026-07-15 | |
| Mid TWO SIGMA SECURITIES, LLC | $20,544 | 0.05% | 13,976 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $19,404 | 0.05% | 13,200 | Put | 2026-09-02 | |
| Mega Qube Research & Technologies Ltd Exempt adviser | $18,667 | 0.05% | 12,699 | Shares | 2026-08-14 | |
| Large NewEdge Advisors, LLC Registered adviser | $17,640 | 0.05% | 12,000 | Shares | 2026-08-12 | |
| Mega Creative Planning Registered adviser | $17,640 | 0.05% | 12,000 | Shares | 2026-08-13 | |
| Large OSAIC HOLDINGS, INC. Holding company | $15,876 | 0.04% | 10,800 | Shares | 2026-08-14 | |
| Small FORTEM FINANCIAL GROUP, LLC Registered adviser | $13,300 | 0.03% | 10,000 | Shares | 2026-10-20 | |
| Large FEDERATED HERMES, INC. Adviser | $11,002 | 0.03% | 7,485 | Shares | 2026-08-12 | |
| Mid SBI Securities Co., Ltd. Non-US | $10,425 | 0.03% | 7,092 | Shares | 2026-07-23 | |
| Large Federation des caisses Desjardins du Quebec | $9,555 | 0.02% | 6,500 | Shares | 2026-08-14 | |
| Small Markowski Investments Registered adviser | $8,085 | 0.02% | 5,500 | Shares | 2026-08-13 | |
| Mega CITIGROUP INC Bank | $6,906 | 0.02% | 4,698 | Shares | 2026-08-03 | |
| Mid SIGNATUREFD, LLC Registered adviser | $5,145 | 0.01% | 3,500 | Shares | 2026-07-24 | |
| Mega JPMORGAN CHASE & CO Bank | $4,323 | 0.01% | 2,942 | Shares | 2026-08-12 | |
| Large Rockefeller Capital Management L.P. Registered adviser | $2,940 | 0.01% | 2,000 | Shares | 2026-08-13 | |
| Mega BARCLAYS PLC Bank | $2,341 | 0.01% | 1,593 | Shares | 2026-08-14 | |
| Mega BNP PARIBAS ARBITRAGE, SA Non-US | $1,547 | 0.00% | 1,053 | Shares | 2026-08-13 | |
| Small Fortitude Family Office, LLC Registered adviser | $603 | 0.00% | 454 | Shares | 2026-10-14 | |
| Mid Global Retirement Partners, LLC | $551 | 0.00% | 375 | Shares | 2026-08-06 | |
| Small Glen Eagle Advisors, LLC Registered adviser | $367 | 0.00% | 250 | Shares | 2026-08-14 | |
| Mega JONES FINANCIAL COMPANIES LLLP | $188 | 0.00% | 128 | Shares | 2026-08-14 | |
| Small Allied Private Wealth LLC Registered adviser | $180 | 0.00% | 123 | Shares | 2026-07-09 | |
| Mega ROYAL BANK OF CANADA Bank | $145 | 0.00% | 99 | Shares | 2026-08-14 | |
| Small Caitong International Asset Management Co., Ltd | $99 | 0.00% | 68 | Shares | 2026-08-05 | |
| Mega WELLS FARGO & COMPANY/MN Bank | $0 | 0.00% | 0 | Shares | 2026-08-14 |