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MBX · MBX Biosciences, Inc. · Shareholders & Ownership

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$52.97 +2.68 (+5.33%) At close · Oct 27 Q2 2025 earnings call transcript
Market Cap
$2.42B
Shares
48.16M
Volume · Oct 27 493.02K Avg daily vol (3M) 521.8K

Every disclosed holder of MBX in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

Who Owns MBX

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

No chart: the summed disclosures exceed shares outstanding, so they are not parts of one whole.

Holder group Shares % Out
Institutional (13F) 55,537,518 115.32%
Insiders (Forms 3, 4, 5) 10,621,437 22.05%
13D/G-only blocks 5,631,880 11.69%
Remaining 23,630,739 -49.07%
Registered funds (N-PORT, not summed) 13,899,117 28.86%

Shares outstanding: 48,160,096, the issuer's latest cover-page count restated onto today's split basis.

Remaining is negative: the summed disclosures exceed shares outstanding, as when filings are dated at different times or holders that do not disclose their links count the same shares. It is flagged, not clipped.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of MBX

# Holder Shares
1
Frazier Life Sciences Management, L.P.
13F CIK 1892134 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
6,652,013
2
FMR LLC
13F CIK 315066 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
5,322,885
2.1
FMR LLC
13G CIK 315066 · Holding company · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
5,322,884
2.2
Fidelity Advisor Biotechnology Fund
Fund S000005321 · Registered fund · Jul 31, 2026
Fidelity Advisor Series VII, not summed
817,600
2.3
Select Health Care Portfolio
Fund S000007466 · Registered fund · Aug 31, 2026
Fidelity Select Portfolios, not summed
680,000
2.4
Fidelity Stock Selector Small Cap Fund
Fund S000005453 · Registered fund · Jul 31, 2026
Fidelity Capital Trust, not summed
636,100
2.5
Fidelity Small Cap Growth Fund
Fund S000007193 · Registered fund · Jul 31, 2026
Fidelity Securities Fund, not summed
416,420
3
Heron Patrick J
Insider CIK 1365617 · Sep 26, 2025
Director, issuer-wide
5,219,440
4
WELLINGTON MANAGEMENT GROUP LLP
13F CIK 902219 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
4,977,523
4.1
WELLINGTON MANAGEMENT GROUP LLP
13G CIK 902219 · Holding company · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
4,977,523
5
GORDON CARL L
Insider CIK 1282930 · Feb 18, 2025
Director, issuer-wide
4,002,887
6
NEA Management Company, LLC
13F CIK 1512848 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
3,614,486
7
New Enterprise Associates 17, L.P.
13D CIK 1768564 · Unknown · Nov 6, 2025
Item 4 purpose: Passive investment
3,614,486
8
BlackRock, Inc.
13F CIK 2012383 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
3,323,672
8.1
BlackRock, Inc.
13G CIK 2012383 · Holding company · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
2,628,181
8.2
iShares Russell 2000 ETF
Fund S000004344 · Registered fund · Jun 30, 2026
iShares Trust, not summed
796,629
8.3
BlackRock Health Sciences Opportunities Portfolio
Fund S000001877 · Registered fund · Aug 31, 2026
BlackRock Funds, not summed
333,350
8.4
iShares Russell 2000 Growth ETF
Fund S000004343 · Registered fund · Jun 30, 2026
iShares Trust, not summed
286,482
8.5
iShares Biotechnology ETF
Fund S000004350 · Registered fund · Jun 30, 2026
iShares Trust, not summed
207,795
9
ORBIMED ADVISORS LLC
13D CIK 1055951 · Registered investment adviser · Aug 6, 2026
Item 4 purpose: none of the classified purposes
not summed
3,074,853
9.1
ORBIMED ADVISORS LLC
Insider CIK 1055951 · Feb 18, 2025
10% Owner, issuer-wide, not summed
4,002,887
9.2
ORBIMED ADVISORS LLC
13F CIK 1055951 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
3,428,736
10
Paradigm Biocapital Advisors LP
13F CIK 1855655 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
2,508,015
11
Norwest Venture Partners XVI, LP
13D CIK 1876200 · Unknown · Sep 26, 2025
Item 4 purpose: not restated by this amendment, the earlier 13D's purpose stands
not summed
2,136,335
12
NVP ASSOCIATES, LLC
13F CIK 1545692 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
2,136,335
13
Wellington Biomedical Innovation Master Investors (Cayman) II, L.P.
13G CIK 1903360 · Unknown · Sep 30, 2025
Rule 13d-1(c), passive investor
2,017,394
14
Deep Track Capital, LP
13F CIK 1856083 · Investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,732,569
14.1
Deep Track Capital, LP
13G CIK 1856083 · Investment adviser · Jun 30, 2026
Rule 13d-1(c), passive investor, not summed
1,732,569
15
Polar Capital Holdings Plc
13F CIK 1837309 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,608,514
16
VANGUARD CAPITAL MANAGEMENT LLC
13F CIK 2100119 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,477,388
17
James N. Topper
13D CIK 1863769 · Unknown · Aug 6, 2026
Item 4 purpose: none of the classified purposes
not summed
1,429,573
18
Hawryluk P. Kent
Insider CIK 1673991 · May 6, 2026
Director, President & CEO, issuer-wide
1,214,444
18.1
P. Kent Hawryluk
13G CIK 1673991 · Unknown · Sep 30, 2025
Rule 13d-1(d), exempt investor, not summed
1,995,759
19
Aaron Wealth Advisors LLC
13F CIK 1812198 · Registered investment adviser · Sep 30, 2026
1,175,771
20
VANGUARD TOTAL STOCK MARKET INDEX FUND
Fund S000002848 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
1,135,375
21
Driehaus Capital Management LLC
13F CIK 938206 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
1,056,579
21.1
Driehaus Micro Cap Growth Fund
Fund S000042829 · Registered fund · Jun 30, 2026
Driehaus Mutual Funds, not summed
118,759
22
Kynam Capital Management, LP
13F CIK 1907884 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
934,799
23
Woodline Partners LP
13F CIK 1784547 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
900,092
24
EVENTIDE ASSET MANAGEMENT, LLC
13F CIK 1442891 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
873,492
24.1
Eventide Healthcare & Life Sciences Fund
Fund S000039514 · Registered fund · Jun 30, 2026
MUTUAL FUND SERIES TRUST, not summed
873,492
25
STATE STREET CORP
13F CIK 93751 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
864,466
25.1
State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF
Fund S000012321 · Registered fund · Jun 30, 2026
SPDR SERIES TRUST, not summed
210,962
25.2
STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO
Fund S000050332 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
10,300
25.3
State Street Total Return V.I.S. Fund
Fund S000001637 · Registered fund · Jun 30, 2026
STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed
783
25.4
State Street Balanced Index Fund
Fund S000082802 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
200
26
PRICE T ROWE ASSOCIATES INC /MD/
13F CIK 80255 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
814,807
26.1
T. Rowe Price Health Sciences Fund, Inc.
Fund S000002088 · Registered fund · Jun 30, 2026
T. ROWE PRICE HEALTH SCIENCES FUND, INC., not summed
586,309
26.2
T. Rowe Price Health Sciences Portfolio
Fund S000002083 · Registered fund · Jun 30, 2026
T. ROWE PRICE EQUITY SERIES, INC., not summed
38,917
26.3
T. Rowe Price Extended Equity Market Index Fund
Fund S000002090 · Registered fund · Jun 30, 2026
T. ROWE PRICE INDEX TRUST, INC., not summed
7,119
26.4
T. Rowe Price Small-Cap Index Fund
Fund S000051327 · Registered fund · Jun 30, 2026
T. ROWE PRICE INDEX TRUST, INC., not summed
4,680
27
Parkman Healthcare Partners LLC
13F CIK 1777015 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
800,173
28
GEODE CAPITAL MANAGEMENT, LLC
13F CIK 1214717 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
773,072
29
BRAIDWELL LP
13F CIK 1920938 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
710,880
30
TCG Crossover Management, LLC
13F CIK 1839948 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
650,000
31
Cormorant Asset Management, LP
13F CIK 1583977 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
550,000
32
Soleus Capital Management, L.P.
13F CIK 1802630 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
515,279
33
GOLDMAN SACHS GROUP INC
13F CIK 886982 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
459,005
33.1
Goldman Sachs Small Cap Equity Insights Fund
Fund S000009329 · Registered fund · Jul 31, 2026
Goldman Sachs Trust, not summed
8,833
33.2
Goldman Sachs Small Cap Growth Insights Fund
Fund S000014930 · Registered fund · Jul 31, 2026
Goldman Sachs Trust, not summed
8,771
33.3
Goldman Sachs ActiveBeta(R) U.S. Small Cap Equity ETF
Fund S000048296 · Registered fund · Aug 31, 2026
Goldman Sachs ETF Trust, not summed
8,094
33.4
Multi-Manager U.S. Small Cap Equity Fund
Fund S000051363 · Registered fund · Apr 30, 2026
Goldman Sachs Trust II, not summed
5,828
33.5
Goldman Sachs Variable Insurance Trust Small Cap Equity Insights Fund
Fund S000009355 · Registered fund · Jun 30, 2026
Goldman Sachs Variable Insurance Trust, not summed
1,759
34
MARSHALL WACE, LLP
13F CIK 1318757 · Exempt reporting adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
401,885
35
EcoR1 Capital, LLC
13F CIK 1587114 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
388,500
36
VANGUARD PORTFOLIO MANAGEMENT LLC
13F CIK 2100121 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
346,717
37
VANGUARD EXTENDED MARKET INDEX FUND
Fund S000002841 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
305,998
38
BANK OF AMERICA CORP /DE/
13F CIK 70858 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
298,927
39
Rock Springs Capital Management LP
13F CIK 1595725 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
298,218
40
Candriam S.C.A.
13F CIK 1537014 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
289,893
41
UBS Group AG
13F CIK 1610520 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
272,747
42
Opaleye Management Inc.
13F CIK 1595855 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
260,000
43
FRANKLIN RESOURCES INC
13F CIK 38777 · Investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
252,665
43.1
Franklin Biotechnology Discovery Fund
Fund S000006882 · Registered fund · Jul 31, 2026
Franklin Strategic Series, not summed
85,528
44
Schonfeld Strategic Advisors LLC
13F CIK 1665241 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
248,670
45
MORGAN STANLEY
13F CIK 895421 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
248,558
46
NORTHERN TRUST CORP
13F CIK 73124 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
246,678
46.1
Small Cap Index Fund
Fund S000001245 · Registered fund · Jun 30, 2026
Northern Funds, not summed
15,685
46.2
FlexShares Morningstar US Market Factor Tilt Index Fund
Fund S000033312 · Registered fund · Jul 31, 2026
FlexShares Trust, not summed
1,264
47
DIMENSIONAL FUND ADVISORS LP
13F CIK 354204 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
233,700
47.1
Dimensional U.S. Small Cap ETF
Fund S000070906 · Registered fund · Jul 31, 2026
Dimensional ETF Trust, not summed
75,910
47.2
U.S. SMALL CAP PORTFOLIO
Fund S000000971 · Registered fund · Jul 31, 2026
DFA INVESTMENT DIMENSIONS GROUP INC, not summed
49,476
47.3
U.S. MICRO CAP PORTFOLIO
Fund S000000948 · Registered fund · Jul 31, 2026
DFA INVESTMENT DIMENSIONS GROUP INC, not summed
48,432
47.4
Dimensional U.S. Core Equity 2 ETF
Fund S000070903 · Registered fund · Jul 31, 2026
Dimensional ETF Trust, not summed
16,676
47.5
Dimensional U.S. Equity Market ETF
Fund S000070902 · Registered fund · Jul 31, 2026
Dimensional ETF Trust, not summed
5,882
48
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F CIK 884546 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
233,095
48.1
Schwab U.S. Small-Cap ETF
Fund S000026636 · Registered fund · Aug 31, 2026
SCHWAB STRATEGIC TRUST, not summed
127,415
48.2
Schwab Small-Cap Index Fund
Fund S000005912 · Registered fund · Jul 31, 2026
SCHWAB CAPITAL TRUST, not summed
75,383
48.3
Schwab Total Stock Market Index Fund
Fund S000005913 · Registered fund · Jul 31, 2026
SCHWAB CAPITAL TRUST, not summed
15,891
48.4
Schwab U.S. Broad Market ETF
Fund S000026631 · Registered fund · Aug 31, 2026
SCHWAB STRATEGIC TRUST, not summed
15,071
49
MILLENNIUM MANAGEMENT LLC
13F CIK 1273087 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
226,151
50
Tetragon Partners GP Ltd
13F CIK 1515070 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
203,543

58 more nested rows are not shown here; Every filing lists them all.

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 273 holders

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Key facts CIK 1776111 CUSIP 55287L101 13F (30d) 22 filings 22 filers Visit website Investor relations