Frazier Life Sciences Management, L.P.
Filing Date
Global Rank
#785
/ 8,700
▲ 165
Top Industry
Biotechnology
97.9%
Period ended 2 months ago
Filed Aug 14, 2026 · 30d
18 quarters · since Mar 2022
Portfolio Concentration
40 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
19.6%
+0.8 pts
Top 5
56.8%
−0.0 pts
Top 10
73.8%
−1.8 pts
HHI
856
Diversified−13
Portfolio Trend
18 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $4,592,080,302 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
8 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| ALLO | Allogene Therapeutics, Inc. | +18,650,000 | 22,446,668 | $46,689,069 | |
| AURA | Aura Biosciences, Inc. | +2,000,000 | 7,100,000 | $50,410,000 | |
| NAMS | NewAmsterdam Pharma Co N.V. | +1,145,128 | 18,589,235 | $623,725,004 | |
| MNKD | Mannkind Corp | +700,000 | 6,600,000 | $28,116,000 | |
| MAZE | Maze Therapeutics, Inc. | +465,641 | 5,032,915 | $150,182,183 | |
| LXEO | Lexeo Therapeutics, Inc. | +400,000 | 4,824,725 | $22,459,094 | |
| ERAS | Erasca, Inc. | +300,000 | 24,975,188 | $457,545,444 | |
| ASND | Ascendis Pharma A/S | +91,822 | 225,155 | $60,053,341 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
6 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| PBLS | Parabilis Medicines, Inc. | 1,920,805 | $52,572,432 | |
| ACHV | Achieve Life Sciences, Inc. | 7,614,836 | $49,724,879 | |
| DSGN | Design Therapeutics, Inc. | 1,809,854 | $26,188,587 | |
| STTK | Shattuck Labs, Inc. | 3,750,000 | $26,025,000 | |
| KLRA | Kailera Therapeutics, Inc. | 1,100,000 | $24,233,000 | |
| RLAY | Relay Therapeutics, Inc. | 1,015,693 | $19,003,616 | |
| No positions match the current search. | ||||
40 tracked positions ·
$4,592,080,302 total
· filing declares
41 positions · $4,592,076,814
· as of Jun 30, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| MIRM |
Mirum Pharmaceuticals, Inc.
Healthcare
|
Held | 7,679,684 | $899,060,605 | 19.58% | |
| NAMS |
NewAmsterdam Pharma Co N.V.
Healthcare
|
Added | 18,589,235 | $623,725,004 | 13.58% | |
| ERAS |
Erasca, Inc.
Healthcare
|
Added | 24,975,188 | $457,545,444 | 9.96% | |
| MBX |
MBX Biosciences, Inc.
Healthcare
|
Held | 6,652,013 | $367,191,117 | 8.00% | |
| ARQT |
Arcutis Biotherapeutics, Inc.
Healthcare
|
Held | 9,874,511 | $258,909,678 | 5.64% | |
| TRVI |
Trevi Therapeutics, Inc.
Healthcare
|
Reduced | 9,939,447 | $185,370,686 | 4.04% | |
| KRYS |
Krystal Biotech, Inc.
Healthcare
|
Held | 481,307 | $178,887,372 | 3.90% | |
| MAZE |
Maze Therapeutics, Inc.
Healthcare
|
Added | 5,032,915 | $150,182,183 | 3.27% | |
| PHAT |
Phathom Pharmaceuticals, Inc.
Healthcare
|
Held | 12,466,489 | $135,261,405 | 2.95% | |
| PVLA |
Palvella Therapeutics, Inc.
Healthcare
|
Held | 882,400 | $134,848,368 | 2.94% | |
| BBIO |
BridgeBio Pharma, Inc.
Healthcare
|
Reduced | 1,548,139 | $115,305,392 | 2.51% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
Held | 1,354,852 | $99,093,875 | 2.16% | |
| CYTK |
Cytokinetics Inc
Healthcare
|
Held | 1,159,879 | $98,810,092 | 2.15% | |
| DYN |
Dyne Therapeutics, Inc.
Healthcare
|
Held | 3,153,082 | $70,029,951 | 1.53% | |
| ASND |
Ascendis Pharma A/S
Healthcare
|
Added | 225,155 | $60,053,341 | 1.31% | |
| SVRA |
Savara Inc
Healthcare
|
Held | 9,720,852 | $59,880,448 | 1.30% | |
| PBLS |
Parabilis Medicines, Inc.
Healthcare
|
NEW | 1,920,805 | $52,572,432 | 1.14% | |
| AURA |
Aura Biosciences, Inc.
Healthcare
|
Added | 7,100,000 | $50,410,000 | 1.10% | |
| ACHV |
Achieve Life Sciences, Inc.
Healthcare
|
NEW | 7,614,836 | $49,724,879 | 1.08% | |
| VOR |
Vor Biopharma Inc.
Healthcare
|
Held | 2,543,939 | $46,833,916 | 1.02% | |
| ALLO |
Allogene Therapeutics, Inc.
Healthcare
|
Added | 22,446,668 | $46,689,069 | 1.02% | |
| TARS |
Tarsus Pharmaceuticals, Inc.
Healthcare
|
Held | 728,644 | $45,860,853 | 1.00% | |
| BCRX |
Biocryst Pharmaceuticals Inc
Healthcare
|
Held | 4,009,240 | $40,092,400 | 0.87% | |
| ALKS |
Alkermes plc.
Healthcare
|
Held | 700,647 | $36,713,902 | 0.80% | |
| ACAD |
Acadia Pharmaceuticals Inc
Healthcare
|
Held | 1,438,198 | $36,386,409 | 0.79% | |
| ZLAB |
Zai Lab Ltd
Healthcare
|
Held | 1,902,320 | $36,144,080 | 0.79% | |
| MNKD |
Mannkind Corp
Healthcare
|
Added | 6,600,000 | $28,116,000 | 0.61% | |
| DSGN |
Design Therapeutics, Inc.
Healthcare
|
NEW | 1,809,854 | $26,188,587 | 0.57% | |
| ACRS |
Aclaris Therapeutics, Inc.
Healthcare
|
Held | 4,925,374 | $26,055,228 | 0.57% | |
| STTK |
Shattuck Labs, Inc.
Healthcare
|
NEW | 3,750,000 | $26,025,000 | 0.57% | |
| KLRA |
Kailera Therapeutics, Inc.
Healthcare
|
NEW | 1,100,000 | $24,233,000 | 0.53% | |
| GLUE |
Monte Rosa Therapeutics, Inc.
Healthcare
|
Held | 1,000,000 | $24,200,000 | 0.53% | |
| LXEO |
Lexeo Therapeutics, Inc.
Healthcare
|
Added | 4,824,725 | $22,459,094 | 0.49% | |
| RLAY |
Relay Therapeutics, Inc.
Healthcare
|
NEW | 1,015,693 | $19,003,616 | 0.41% | |
| EOLS |
Evolus, Inc.
Healthcare
|
Held | 2,630,665 | $18,256,815 | 0.40% | |
| IMCR |
Immunocore Holdings plc
Healthcare
|
Held | 484,782 | $15,391,828 | 0.34% | |
| VALN |
Valneva SE
Healthcare
|
Held | 2,291,666 | $11,985,413 | 0.26% | |
| AUTL |
Autolus Therapeutics plc
Healthcare
|
Held | 4,447,910 | $7,116,656 | 0.15% | |
| XLO |
Xilio Therapeutics, Inc.
Healthcare
|
Held | 422,505 | $4,047,597 | 0.09% | |
| IBIO |
iBio, Inc.
Healthcare
|
Held | 1,953,467 | $3,418,567 | 0.07% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.