Soleus Capital Management, L.P.
Filing Date
Global Rank
#1,069
/ 8,623
▲ 47
· as of Mar 2026
Top Industry
Biotechnology
55.8%
3Y Alpha vs SPY
+7.8%
Period ended 4 months ago
Filed May 14, 2026 · 3mo
25 quarters · since Mar 2020
Clone Performance
Jul 2023–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+100.9%
SPY
+65.3%
Annualised alpha
+7.9%
Max drawdown
−37.3%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 13 quarters. Past performance does not predict future results.
Portfolio Concentration
93 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
12.1%
+2.1 pts
Top 5
32.8%
+1.6 pts
Top 10
50.3%
+2.2 pts
HHI
380
Diversified+38
Portfolio Trend
25 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $2,469,218,397 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| GERN | Geron Corp | +18,218,659 | 41,508,659 | $61,847,901 | |
| CERS | Cerus Corp | +6,753,700 | 10,753,700 | $19,571,734 | |
| NVCR | NovoCure Ltd | +1,961,726 | 10,492,391 | $114,367,061 | |
| BBNX | Beta Bionics, Inc. | +1,819,936 | 4,354,501 | $43,632,100 | |
| VCEL | Vericel Corp | +1,785,079 | 2,549,079 | $82,003,871 | |
| EOLS | Evolus, Inc. | +1,175,360 | 2,245,360 | $9,228,429 | |
| TGTX | Tg Therapeutics, Inc. | +890,007 | 4,029,319 | $133,853,977 | |
| LUNG | Pulmonx Corp | +750,000 | 2,788,323 | $3,596,936 | |
| TRVI | Trevi Therapeutics, Inc. | +720,000 | 1,620,000 | $19,326,600 | |
| ALKS | Alkermes plc. | +648,500 | 1,970,864 | $69,689,751 | |
| URGN | UroGen Pharma Ltd. | +577,000 | 727,000 | $13,071,460 | |
| EWTX | Edgewise Therapeutics, Inc. | +539,915 | 1,449,915 | $45,672,322 | |
| TNGX | Tango Therapeutics, Inc. | +440,000 | 450,000 | $9,414,000 | |
| PODD | Insulet Corp | +412,500 | 562,500 | $118,035,000 | |
| ANIP | Ani Pharmaceuticals Inc | +334,000 | 820,243 | $63,076,686 | |
| VCYT | Veracyte, Inc. | +309,912 | 319,912 | $10,304,365 | |
| INSP | Inspire Medical Systems, Inc. | +276,900 | 576,299 | $29,725,502 | |
| NPCE | NeuroPace Inc | +228,999 | 2,932,207 | $38,558,522 | |
| KRYS | Krystal Biotech, Inc. | +212,028 | 1,153,087 | $297,865,433 | |
| UTHR | UNITED THERAPEUTICS Corp | +127,187 | 187,187 | $110,998,147 | |
| INBX | Inhibrx Biosciences, Inc. | +106,000 | 131,000 | $8,807,130 | |
| ORGO | Organogenesis Holdings Inc. | +100,000 | 10,085,951 | $23,903,703 | |
| NTRA | Natera, Inc. | +99,000 | 119,000 | $23,798,810 | |
| KIDS | Orthopediatrics Corp | +90,000 | 615,447 | $9,767,143 | |
| JSPR | Jasper Therapeutics, Inc. | +76,312 | 276,312 | $242,049 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| DXCM | Dexcom Inc | −1,157,094 | 140,000 | $8,792,000 | |
| IMVT | Immunovant, Inc. | −880,000 | 230,000 | $5,713,200 | |
| ELVN | Enliven Therapeutics, Inc. | −794,131 | 230,869 | $9,050,064 | |
| BMRN | Biomarin Pharmaceutical Inc | −669,428 | 650,572 | $36,750,812 | |
| TWST | Twist Bioscience Corp | −635,173 | 1,226,629 | $58,289,410 | |
| AXGN | Axogen, Inc. | −527,685 | 679,170 | $22,500,902 | |
| CELC | Celcuity Inc. | −523,880 | 1,284,378 | $146,598,904 | |
| SNDX | Syndax Pharmaceuticals Inc | −520,202 | 1,726,908 | $40,340,570 | |
| RIGL | Rigel Pharmaceuticals Inc | −290,034 | 10,000 | $270,400 | |
| NRIX | Nurix Therapeutics, Inc. | −281,231 | 938,163 | $14,541,526 | |
| RCUS | Arcus Biosciences, Inc. | −260,000 | 451,983 | $9,762,832 | |
| NEO | Neogenomics Inc | −252,504 | 175,000 | $1,298,500 | |
| MBX | MBX Biosciences, Inc. | −230,003 | 178,897 | $5,340,075 | |
| PCVX | Vaxcyte, Inc. | −223,486 | 385,472 | $22,399,777 | |
| ORKA | Oruka Therapeutics, Inc. | −185,000 | 5,000 | $245,250 | |
| MIRM | Mirum Pharmaceuticals, Inc. | −173,308 | 400,306 | $36,980,268 | |
| GMED | Globus Medical Inc | −157,533 | 729,467 | $62,850,876 | |
| CGON | CG Oncology, Inc. | −150,000 | 20,000 | $1,353,600 | |
| ANAB | Anaptysbio, Inc | −129,000 | 6,000 | $332,759 | |
| TYRA | Tyra Biosciences, Inc. | −115,000 | 10,000 | $383,000 | |
| COGT | Cogent Biosciences, Inc. | −110,000 | 10,000 | $384,900 | |
| SEPN | Septerna, Inc. | −108,368 | 275,000 | $6,608,250 | |
| NSPR | InspireMD, Inc. | −104,292 | 1,045,708 | $1,704,504 | |
| ZYME | Zymeworks Inc. | −90,000 | 10,000 | $250,400 | |
| KNSA | Kiniksa Pharmaceuticals International, plc | −65,647 | 521,353 | $25,103,146 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| INDV | Indivior Pharmaceuticals, Inc. | 1,274,000 | $38,831,520 | |
| PGNY | Progyny, Inc. | 2,067,000 | $35,097,660 | |
| MRK | Merck & Co., Inc. | 203,000 | $24,418,870 | |
| ICLR | Icon PLC | 192,000 | $21,246,720 | |
| CNTX | Context Therapeutics Inc. | 6,963,141 | $18,243,429 | |
| VIR | Vir Biotechnology, Inc. | 2,002,000 | $17,937,920 | |
| XENE | Xenon Pharmaceuticals Inc. | 292,000 | $16,979,800 | |
| TVTX | Travere Therapeutics, Inc. | 546,000 | $16,221,660 | |
| TNDM | Tandem Diabetes Care Inc | 783,000 | $15,010,110 | |
| CORT | Corcept Therapeutics Inc | 285,531 | $11,509,754 | |
| SOPH | SOPHiA GENETICS SA | 1,850,000 | $9,157,500 | |
| BDSX | Biodesix Inc | 416,599 | $6,040,685 | |
| RLMD | Relmada Therapeutics, Inc. | 842,106 | $5,861,057 | |
| CGEM | Cullinan Therapeutics, Inc. | 410,200 | $5,828,942 | |
| IMUX | Immunic, Inc. | 4,500,000 | $4,995,000 | |
| LRMR | Larimar Therapeutics, Inc. | 1,066,960 | $4,801,320 | |
| ETON | Eton Pharmaceuticals, Inc. | 166,381 | $4,106,283 | |
| SABS | SAB Biotherapeutics, Inc. | 1,050,000 | $4,021,500 | |
| PRCT | PROCEPT BioRobotics Corp | 160,000 | $4,001,600 | |
| TECX | Tectonic Therapeutic, Inc. | 121,684 | $3,761,252 | |
| IOVA | Iovance Biotherapeutics, Inc. | 1,000,000 | $3,510,000 | |
| MSLE | Satellos Bioscience Inc. | 414,359 | $2,332,841 | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | 28,479 | $1,785,633 | |
| CTMX | CytomX Therapeutics, Inc. | 300,000 | $1,410,000 | |
| RAPP | Rapport Therapeutics, Inc. | 10,000 | $312,900 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
23 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS, INC. | 5,207,284 | $74,151,724 | |
| GSK | GSK plc | 639,000 | $31,336,560 | |
| NBIX | Neurocrine Biosciences Inc | 175,982 | $24,959,527 | |
| TFX | Teleflex Inc | 190,000 | $23,187,600 | |
| CAPR | Capricor Therapeutics, Inc. | 646,390 | $18,654,815 | |
| THC | Tenet Healthcare Corp | 92,500 | $18,381,600 | |
| TERN | Terns Pharmaceuticals, Inc. | 212,710 | $8,593,484 | |
| ERAS | Erasca, Inc. | 2,162,162 | $8,043,242 | |
| BLTE | Belite Bio, Inc | 40,354 | $6,455,025 | |
| ABVX | Abivax S.A. | 45,000 | $6,068,475 | |
| MLTX | MoonLake Immunotherapeutics | 400,000 | $5,272,000 | |
| CALC | CalciMedica, Inc. | 683,904 | $4,506,927 | |
| VKTX | Viking Therapeutics, Inc. | 70,000 | $2,462,600 | |
| QDEL | QuidelOrtho Corp | 75,000 | $2,142,000 | |
| ACLX | Arcellx, Inc. | 30,000 | $1,956,000 | |
| OLMA | Olema Pharmaceuticals, Inc. | 69,874 | $1,746,850 | |
| BCAX | Bicara Therapeutics Inc. | 100,000 | $1,683,000 | |
| KOD | Kodiak Sciences Inc. | 60,000 | $1,677,600 | |
| GRAL | GRAIL, Inc. | 11,000 | $941,490 | |
| GUTS | Fractyl Health, Inc. | 400,000 | $880,000 | |
| MDGL | Madrigal Pharmaceuticals, Inc. | 500 | $291,170 | |
| DYN | Dyne Therapeutics, Inc. | 10,000 | $195,600 | |
| DCTH | Delcath Systems, Inc. | 10,000 | $101,000 | |
| No positions match the current search. | ||||
93 tracked positions ·
$2,469,218,397 total
· filing declares
93 positions · $2,469,218,478
· as of Mar 31, 2026
Showing 1–50
of 93 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| KRYS |
Krystal Biotech, Inc.
Healthcare
|
Added | 1,153,087 | $297,865,433 | 12.06% | |
| CELC |
Celcuity Inc.
Healthcare
|
Reduced | 1,284,378 | $146,598,904 | 5.94% | |
| TGTX |
Tg Therapeutics, Inc.
Healthcare
|
Added | 4,029,319 | $133,853,977 | 5.42% | |
| PODD |
Insulet Corp
Healthcare
|
Added | 562,500 | $118,035,000 | 4.78% | |
| NVCR |
NovoCure Ltd
Healthcare
|
Added | 10,492,391 | $114,367,061 | 4.63% | |
| UTHR |
UNITED THERAPEUTICS Corp
Healthcare
|
Added | 187,187 | $110,998,147 | 4.50% | |
| PRAX |
Praxis Precision Medicines, Inc.
Healthcare
|
Reduced | 330,517 | $106,489,272 | 4.31% | |
| VCEL |
Vericel Corp
Healthcare
|
Added | 2,549,079 | $82,003,871 | 3.32% | |
| ALKS |
Alkermes plc.
Healthcare
|
Added | 1,970,864 | $69,689,751 | 2.82% | |
| ANIP |
Ani Pharmaceuticals Inc
Healthcare
|
Added | 820,243 | $63,076,686 | 2.55% | |
| GMED |
Globus Medical Inc
Healthcare
|
Reduced | 729,467 | $62,850,876 | 2.55% | |
| GERN |
Geron Corp
Healthcare
|
Added | 41,508,659 | $61,847,901 | 2.50% | |
| TWST |
Twist Bioscience Corp
Healthcare
|
Reduced | 1,226,629 | $58,289,410 | 2.36% | |
| EWTX |
Edgewise Therapeutics, Inc.
Healthcare
|
Added | 1,449,915 | $45,672,322 | 1.85% | |
| BBNX |
Beta Bionics, Inc.
Healthcare
|
Added | 4,354,501 | $43,632,100 | 1.77% | |
| ALNY |
Alnylam Pharmaceuticals, Inc.
Healthcare
|
Added | 131,650 | $43,559,035 | 1.76% | |
| SNDX |
Syndax Pharmaceuticals Inc
Healthcare
|
Reduced | 1,726,908 | $40,340,570 | 1.63% | |
| INDV |
Indivior Pharmaceuticals, Inc.
Healthcare
|
NEW | 1,274,000 | $38,831,520 | 1.57% | |
| NPCE |
NeuroPace Inc
Healthcare
|
Added | 2,932,207 | $38,558,522 | 1.56% | |
| LIVN |
LivaNova PLC
Healthcare
|
Added | 582,500 | $37,023,700 | 1.50% | |
| MIRM |
Mirum Pharmaceuticals, Inc.
Healthcare
|
Reduced | 400,306 | $36,980,268 | 1.50% | |
| BMRN |
Biomarin Pharmaceutical Inc
Healthcare
|
Reduced | 650,572 | $36,750,812 | 1.49% | |
| PGNY |
Progyny, Inc.
Healthcare
|
NEW | 2,067,000 | $35,097,660 | 1.42% | |
| INSP |
Inspire Medical Systems, Inc.
Healthcare
|
Added | 576,299 | $29,725,502 | 1.20% | |
| FOCL |
Edap Tms SA
Healthcare
|
Held | 7,309,254 | $27,190,424 | 1.10% | |
| KNSA |
Kiniksa Pharmaceuticals International, plc
Healthcare
|
Reduced | 521,353 | $25,103,146 | 1.02% | |
| MRK |
Merck & Co., Inc.
Healthcare
|
NEW | 203,000 | $24,418,870 | 0.99% | |
| ORGO |
Organogenesis Holdings Inc.
Healthcare
|
Added | 10,085,951 | $23,903,703 | 0.97% | |
| NTRA |
Natera, Inc.
Healthcare
|
Added | 119,000 | $23,798,810 | 0.96% | |
| AXGN |
Axogen, Inc.
Healthcare
|
Reduced | 679,170 | $22,500,902 | 0.91% | |
| PCVX |
Vaxcyte, Inc.
Healthcare
|
Reduced | 385,472 | $22,399,777 | 0.91% | |
| ICLR |
Icon PLC
Healthcare
|
NEW | 192,000 | $21,246,720 | 0.86% | |
| PHVS |
Pharvaris N.V.
Healthcare
|
Held | 702,052 | $19,832,969 | 0.80% | |
| CERS |
Cerus Corp
Healthcare
|
Added | 10,753,700 | $19,571,734 | 0.79% | |
| TRVI |
Trevi Therapeutics, Inc.
Healthcare
|
Added | 1,620,000 | $19,326,600 | 0.78% | |
| IKT |
Inhibikase Therapeutics, Inc.
Healthcare
|
Held | 10,875,000 | $18,270,000 | 0.74% | |
| CNTX |
Context Therapeutics Inc.
Healthcare
|
NEW | 6,963,141 | $18,243,429 | 0.74% | |
| VIR |
Vir Biotechnology, Inc.
Healthcare
|
NEW | 2,002,000 | $17,937,920 | 0.73% | |
| XENE |
Xenon Pharmaceuticals Inc.
Healthcare
|
NEW | 292,000 | $16,979,800 | 0.69% | |
| TVTX |
Travere Therapeutics, Inc.
Healthcare
|
NEW | 546,000 | $16,221,660 | 0.66% | |
| TNDM |
Tandem Diabetes Care Inc
Healthcare
|
NEW | 783,000 | $15,010,110 | 0.61% | |
| NRIX |
Nurix Therapeutics, Inc.
Healthcare
|
Reduced | 938,163 | $14,541,526 | 0.59% | |
| URGN |
UroGen Pharma Ltd.
Healthcare
|
Added | 727,000 | $13,071,460 | 0.53% | |
| SION |
Sionna Therapeutics, Inc.
Healthcare
|
Added | 293,500 | $11,766,415 | 0.48% | |
| CORT |
Corcept Therapeutics Inc
Healthcare
|
NEW | 285,531 | $11,509,754 | 0.47% | |
| JBIO |
Jade Biosciences, Inc.
Healthcare
|
Held | 796,744 | $11,194,253 | 0.45% | |
| VCYT |
Veracyte, Inc.
Healthcare
|
Added | 319,912 | $10,304,365 | 0.42% | |
| IVVD |
Invivyd, Inc.
Healthcare
|
Held | 7,708,727 | $10,021,345 | 0.41% | |
| CCCC |
C4 Therapeutics, Inc.
Healthcare
|
Held | 3,803,942 | $10,004,367 | 0.41% | |
| KIDS |
Orthopediatrics Corp
Healthcare
|
Added | 615,447 | $9,767,143 | 0.40% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.