Soleus Capital Management, L.P.

CIK

1802630

Location

GREENWICH, CT

Portfolio Value

Mid $2,901,982,840

Diversification

Diversified

Filing Date

Global Rank

#1,069 / 8,700 ▲ 216

Top Industry

Biotechnology 60.4%

Period ended 2 months ago

Filed Aug 11, 2026 · 33d

26 quarters · since Mar 2020

Portfolio Concentration

97 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

12.0%

−0.0 pts

Top 5

34.4%

+1.6 pts

Top 10

48.9%

−1.4 pts

HHI

371

Diversified−10

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$2,901,982,840	97

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

25 positions

Ticker	Company	Δ Shares	Shares	Value
RIGL	Rigel Pharmaceuticals Inc	+1,833,504	1,843,504	$72,117,876
INSP	Inspire Medical Systems, Inc.	+1,355,137	1,931,436	$86,161,359
GERN	Geron Corp	+1,300,000	42,808,659	$54,795,083
AVTX	Avalo Therapeutics, Inc.	+1,213,000	1,654,978	$30,583,993
PRCT	PROCEPT BioRobotics Corp	+843,000	1,003,000	$22,647,740
JBIO	Jade Biosciences, Inc.	+753,946	1,550,690	$34,456,331
RCUS	Arcus Biosciences, Inc.	+716,755	1,168,738	$36,032,192
NRIX	Nurix Therapeutics, Inc.	+527,000	1,465,163	$35,544,854
PODD	Insulet Corp	+486,500	1,049,000	$159,710,250
CELC	Celcuity Inc.	+419,940	1,704,318	$178,305,749
MBX	MBX Biosciences, Inc.	+336,382	515,279	$28,443,400
TNGX	Tango Therapeutics, Inc.	+259,000	709,000	$22,163,340
BDSX	Biodesix Inc	+169,359	585,958	$13,213,352
KIDS	Orthopediatrics Corp	+116,697	732,144	$14,005,914
URGN	UroGen Pharma Ltd.	+102,810	829,810	$30,537,008
CNTX	Context Therapeutics Inc.	+100,000	7,063,141	$3,912,980
INSM	INSMED Inc	+80,000	90,250	$9,622,455
ORGO	Organogenesis Holdings Inc.	+55,000	10,140,951	$24,642,510
ANIP	Ani Pharmaceuticals Inc	+47,517	867,760	$71,833,172
BBNX	Beta Bionics, Inc.	+39,213	4,393,714	$68,849,498
UTHR	UNITED THERAPEUTICS Corp	+38,400	225,587	$122,229,804
PHVS	Pharvaris N.V.	+28,855	730,907	$25,274,764
GPCR	Structure Therapeutics Inc.	+27,000	107,000	$5,742,690
IMVT	Immunovant, Inc.	+22,000	252,000	$9,709,560
ARGX	Argenx SE	+16,455	19,955	$18,513,650
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
CERS	Cerus Corp	−8,253,700	2,500,000	$7,300,000
IMUX	Immunic, Inc.	−4,050,000	450,000	$6,916,500
EOLS	Evolus, Inc.	−1,422,932	822,428	$5,707,650
TWST	Twist Bioscience Corp	−1,122,000	104,629	$10,764,231
TGTX	Tg Therapeutics, Inc.	−1,101,424	2,927,895	$160,858,551
VCEL	Vericel Corp	−1,089,927	1,459,152	$64,917,672
VIR	Vir Biotechnology, Inc.	−1,002,000	1,000,000	$10,190,000
EWTX	Edgewise Therapeutics, Inc.	−999,026	450,889	$18,319,620
ALKS	Alkermes plc.	−941,612	1,029,252	$53,932,804
LRMR	Larimar Therapeutics, Inc.	−878,858	188,102	$573,711
IOVA	Iovance Biotherapeutics, Inc.	−850,000	150,000	$624,000
AXGN	Axogen, Inc.	−622,134	57,036	$2,634,492
NVCR	NovoCure Ltd	−578,990	9,913,401	$150,188,025
PGNY	Progyny, Inc.	−465,000	1,602,000	$46,185,660
TRVI	Trevi Therapeutics, Inc.	−440,382	1,179,618	$21,999,875
CCCC	C4 Therapeutics, Inc.	−425,961	3,377,981	$15,775,171
CGEM	Cullinan Therapeutics, Inc.	−360,200	50,000	$910,500
LIVN	LivaNova PLC	−327,543	254,957	$20,965,114
MIRM	Mirum Pharmaceuticals, Inc.	−325,306	75,000	$8,780,250
VCYT	Veracyte, Inc.	−294,912	25,000	$1,468,250
SOPH	SOPHiA GENETICS SA	−285,000	1,565,000	$9,030,050
KNSA	Kiniksa Pharmaceuticals International, plc	−275,000	246,353	$15,754,274
BMRN	Biomarin Pharmaceutical Inc	−275,000	375,572	$21,490,229
CORT	Corcept Therapeutics Inc	−265,878	19,653	$1,708,828
GMED	Globus Medical Inc	−260,545	468,922	$37,049,527
No positions match the current search.

New Positions

Positions the filer opened this quarter

21 positions

Ticker	Company	Shares	Value
ERAS	Erasca, Inc.	2,700,000	$49,464,000
PBLS	Parabilis Medicines, Inc.	1,465,070	$40,098,965
LEGN	Legend Biotech Corp	1,205,000	$34,800,400
UNH	Unitedhealth Group Inc	80,000	$33,250,400
PALI	Palisade Bio, Inc.	13,063,687	$27,303,105
SUPN	Supernus Pharmaceuticals, Inc.	520,000	$24,185,200
NVCT	Nuvectis Pharma, Inc.	1,000,000	$18,390,000
CAPR	Capricor Therapeutics, Inc.	761,737	$18,342,626
PRLD	Prelude Therapeutics Inc	3,378,378	$18,006,754
AVLN	Avalyn Pharma Inc.	419,000	$13,793,480
SYRE	Spyre Therapeutics, Inc.	147,000	$13,050,660
NKTR	Nektar Therapeutics	128,362	$8,960,951
AORT	Artivion, Inc.	388,000	$8,718,360
BLTE	Belite Bio, Inc	50,524	$7,779,938
SLN	Silence Therapeutics plc	630,000	$6,917,400
ANL	Adlai Nortye Group Ltd.	405,523	$4,663,514
ZNTL	Zentalis Pharmaceuticals, Inc.	950,000	$4,607,500
AVBP	ArriVent BioPharma, Inc.	50,000	$1,737,000
SLDB	Solid Biosciences Inc.	150,000	$1,498,500
WGS	GeneDx Holdings Corp.	10,000	$686,500
EQ	Equillium, Inc.	90,000	$288,000
No positions match the current search.

Sold Out

Positions the filer fully exited

17 positions

Ticker	Company	Shares	Value
PCVX	Vaxcyte, Inc.	385,472	$22,399,777
ICLR	Icon PLC	192,000	$21,246,720
TVTX	Travere Therapeutics, Inc.	546,000	$16,221,660
INBX	Inhibrx Biosciences, Inc.	131,000	$8,807,130
DXCM	Dexcom Inc	140,000	$8,792,000
ETON	Eton Pharmaceuticals, Inc.	166,381	$4,106,283
ARWR	Arrowhead Pharmaceuticals, Inc.	28,479	$1,785,633
CTMX	CytomX Therapeutics, Inc.	300,000	$1,410,000
COGT	Cogent Biosciences, Inc.	10,000	$384,900
TYRA	Tyra Biosciences, Inc.	10,000	$383,000
STAA	Staar Surgical Co	20,000	$374,000
ANAB	Anaptysbio, Inc	6,000	$332,759
RAPP	Rapport Therapeutics, Inc.	10,000	$312,900
ZYME	Zymeworks Inc.	10,000	$250,400
LBRX	Lb Pharmaceuticals Inc	10,000	$246,600
ORKA	Oruka Therapeutics, Inc.	5,000	$245,250
JSPR	Jasper Therapeutics, Inc.	276,312	$242,049
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

97 tracked positions · $2,901,982,840 total · filing declares 97 positions · $2,901,979,696 · as of Jun 30, 2026

All sectors Healthcare

Showing 1–50 of 97 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
KRYS	Krystal Biotech, Inc. Healthcare	Reduced	939,254	-213,833	$349,092,534	+17.2%	12.03%
CELC	Celcuity Inc. Healthcare	Added	1,704,318	+419,940	$178,305,749	+21.6%	6.14%
TGTX	Tg Therapeutics, Inc. Healthcare	Reduced	2,927,895	-1,101,424	$160,858,551	+20.2%	5.54%
PODD	Insulet Corp Healthcare	Added	1,049,000	+486,500	$159,710,250	+35.3%	5.50%
NVCR	NovoCure Ltd Healthcare	Reduced	9,913,401	-578,990	$150,188,025	+31.3%	5.18%
UTHR	UNITED THERAPEUTICS Corp Healthcare	Added	225,587	+38,400	$122,229,804	+10.1%	4.21%
INSP	Inspire Medical Systems, Inc. Healthcare	Added	1,931,436	+1,355,137	$86,161,359	+189.9%	2.97%
RIGL	Rigel Pharmaceuticals Inc Healthcare	Added	1,843,504	+1,833,504	$72,117,876	+26570.8%	2.49%
ANIP	Ani Pharmaceuticals Inc Healthcare	Added	867,760	+47,517	$71,833,172	+13.9%	2.48%
BBNX	Beta Bionics, Inc. Healthcare	Added	4,393,714	+39,213	$68,849,498	+57.8%	2.37%
VCEL	Vericel Corp Healthcare	Reduced	1,459,152	-1,089,927	$64,917,672	−20.8%	2.24%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Reduced	177,517	-153,000	$59,430,916	−44.2%	2.05%
GERN	Geron Corp Healthcare	Added	42,808,659	+1,300,000	$54,795,083	−11.4%	1.89%
ALKS	Alkermes plc. Healthcare	Reduced	1,029,252	-941,612	$53,932,804	−22.6%	1.86%
ERAS	Erasca, Inc. Healthcare	NEW	2,700,000	NEW	$49,464,000	NEW	1.70%
NPCE	NeuroPace Inc Healthcare	Reduced	2,911,122	-21,085	$46,257,728	+20.0%	1.59%
PGNY	Progyny, Inc. Healthcare	Reduced	1,602,000	-465,000	$46,185,660	+31.6%	1.59%
INDV	Indivior Pharmaceuticals, Inc. Healthcare	Reduced	1,064,000	-210,000	$43,655,920	+12.4%	1.50%
PBLS	Parabilis Medicines, Inc. Healthcare	NEW	1,465,070	NEW	$40,098,965	NEW	1.38%
FOCL	Edap Tms SA Healthcare	Held	7,309,254	0	$37,861,935	+39.2%	1.30%
GMED	Globus Medical Inc Healthcare	Reduced	468,922	-260,545	$37,049,527	−41.1%	1.28%
RCUS	Arcus Biosciences, Inc. Healthcare	Added	1,168,738	+716,755	$36,032,192	+269.1%	1.24%
SNDX	Syndax Pharmaceuticals Inc Healthcare	Reduced	1,628,039	-98,869	$35,588,932	−11.8%	1.23%
NRIX	Nurix Therapeutics, Inc. Healthcare	Added	1,465,163	+527,000	$35,544,854	+144.4%	1.22%
LEGN	Legend Biotech Corp Healthcare	NEW	1,205,000	NEW	$34,800,400	NEW	1.20%
JBIO	Jade Biosciences, Inc. Healthcare	Added	1,550,690	+753,946	$34,456,331	+207.8%	1.19%
UNH	Unitedhealth Group Inc Healthcare	NEW	80,000	NEW	$33,250,400	NEW	1.15%
AVTX	Avalo Therapeutics, Inc. Healthcare	Added	1,654,978	+1,213,000	$30,583,993	+363.5%	1.05%
URGN	UroGen Pharma Ltd. Healthcare	Added	829,810	+102,810	$30,537,008	+133.6%	1.05%
MBX	MBX Biosciences, Inc. Healthcare	Added	515,279	+336,382	$28,443,400	+432.6%	0.98%
PALI	Palisade Bio, Inc. Healthcare	NEW	13,063,687	NEW	$27,303,105	NEW	0.94%
PHVS	Pharvaris N.V. Healthcare	Added	730,907	+28,855	$25,274,764	+27.4%	0.87%
ORGO	Organogenesis Holdings Inc. Healthcare	Added	10,140,951	+55,000	$24,642,510	+3.1%	0.85%
SUPN	Supernus Pharmaceuticals, Inc. Healthcare	NEW	520,000	NEW	$24,185,200	NEW	0.83%
PRCT	PROCEPT BioRobotics Corp Healthcare	Added	1,003,000	+843,000	$22,647,740	+466.0%	0.78%
TNGX	Tango Therapeutics, Inc. Healthcare	Added	709,000	+259,000	$22,163,340	+135.4%	0.76%
IKT	Inhibikase Therapeutics, Inc. Healthcare	Held	10,875,000	0	$22,076,250	+20.8%	0.76%
TRVI	Trevi Therapeutics, Inc. Healthcare	Reduced	1,179,618	-440,382	$21,999,875	+13.8%	0.76%
BMRN	Biomarin Pharmaceutical Inc Healthcare	Reduced	375,572	-275,000	$21,490,229	−41.5%	0.74%
LIVN	LivaNova PLC Healthcare	Reduced	254,957	-327,543	$20,965,114	−43.4%	0.72%
ARGX	Argenx SE Healthcare	Added	19,955	+16,455	$18,513,650	+624.4%	0.64%
NVCT	Nuvectis Pharma, Inc. Healthcare	NEW	1,000,000	NEW	$18,390,000	NEW	0.63%
CAPR	Capricor Therapeutics, Inc. Healthcare	NEW	761,737	NEW	$18,342,626	NEW	0.63%
EWTX	Edgewise Therapeutics, Inc. Healthcare	Reduced	450,889	-999,026	$18,319,620	−59.9%	0.63%
PRLD	Prelude Therapeutics Inc Healthcare	NEW	3,378,378	NEW	$18,006,754	NEW	0.62%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Reduced	267,000	-25,000	$16,116,120	−5.1%	0.56%
CCCC	C4 Therapeutics, Inc. Healthcare	Reduced	3,377,981	-425,961	$15,775,171	+57.7%	0.54%
KNSA	Kiniksa Pharmaceuticals International, plc Healthcare	Reduced	246,353	-275,000	$15,754,274	−37.2%	0.54%
KIDS	Orthopediatrics Corp Healthcare	Added	732,144	+116,697	$14,005,914	+43.4%	0.48%
AVLN	Avalyn Pharma Inc. Healthcare	NEW	419,000	NEW	$13,793,480	NEW	0.48%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.