Rock Springs Capital Management LP

Registered adviser

CIK

1595725

Location

Baltimore, MD

Portfolio Value

Mid $2,048,809,888

Diversification

Diversified

Filing Date

Global Rank

#1,573 / 8,818 ▲ 45

Top Industry

Biotechnology 73.3%

Period ended 4 months ago

Filed Aug 14, 2026 · 2mo

26 quarters · since Mar 2020

Regulatory profile

From Form ADV, the SEC filer profile, 13D/13G type codes and N-CEN, never from the name.

Holder type

Registered adviser

Form ADV roster, Oct 1, 2026

Form ADV adviser

CRD 168648

Roster of Oct 1, 2026

Regulatory AUM

$2,426,287,072

Main clients

Pooled investment vehicles (100% of AUM)

Private funds

2 funds · Hedge funds

Focus by fund count, roster of Oct 1, 2026

$2,426,287,072 gross assets

LEI

5493004NKG0T3VM7NZ08

Private funds on Schedule D 7.B.(1)

As filed Mar 27, 2024; SEC's bulk Form ADV archive ends with 2024 filings.

$5,768,717,819 gross assets in 2 funds Hedge funds $5,768,717,819 (2)

Form ADV history

Monthly rosters from Dec 2019; each row is a run with the same figures, newest first.

Rosters	Regulatory AUM	Main clients
Apr 2026 to Oct 2026	$2,426,287,072	Pooled investment vehicles (100%)
Apr 2025 to Mar 2026	$3,324,419,780	Pooled investment vehicles (100%)
Apr 2024 to Mar 2025	$5,768,717,819	Pooled investment vehicles (100%)
May 2023 to Mar 2024	$5,716,429,633	Pooled investment vehicles (100%)
Apr 2023	$5,716,429,633	Pooled investment vehicles (100%)
Apr 2022 to Mar 2023	$5,884,695,405	Pooled investment vehicles (100%)

3 earlier changes not shown.

Portfolio style

Measured from the filed 13F common-share book for Jun 30, 2026, never from the firm's own description.

Style

Diversified active

Top 10 weight 44.0%, 32.7 effective positions, active share 94.8% against the Russell 2000 as of 2026-06-30; it meets none of the index-like, systematic-like or concentrated tests

Turnover

Low turnover

26.8% over the last four quarters (under 30%)

Horizon

Long horizon

Value-weighted holding period 15.6 quarters (12+), a floor since 31.3% of the book was already held when coverage starts

Closest benchmark: the Russell 2000 as of 2026-06-30, active share 94.8%; sector active share 90.9% against the combined 13F book's sector weights.

Over time 26 measured quarters

How the bands are measured

Style bands measure the filed 13F common-share book each closed quarter, tested in this order. Unknown: under $10,000,000 of valued equity or 5 stocks. Index-like (100+ stocks): active share of 20% or less against the closest benchmark, which is the S&P 500, S&P MidCap 400, S&P SmallCap 600, Russell 1000, Russell 2000, Nasdaq-100 or Dow Jones Industrial Average (weighted by an index-tracking fund's reported holdings or the index's constituents nearest the quarter end, over the names resolved to companies, and only when those are 90%+ of its weight) or every 13F filer's combined book, or index series holding 80%+ of the registered fund assets it advises (N-CEN) and equal to 50%+ of its book. Systematic-like: 500+ stocks, 100%+ annual turnover and a top 10 weight of 25% or less. Concentrated: a top 10 weight of 60%+ or 12 or fewer effective positions. Diversified active: none of these. Turnover is the smaller of buys and sells over average equity value, summed over four quarters: low under 30%, high 100%+. Horizon is the value-weighted number of quarters each position has been held: short under 4, long 12+.

Clone Performance

Build a hypothetical price-return history from this filer's public 13F holdings.

View clone backtest

Portfolio Concentration

104 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

10.1%

+3.2 pts

Top 5

31.1%

+4.9 pts

Top 10

44.0%

+3.4 pts

HHI

305

Diversified+49

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$2,048,809,888	104

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

25 positions

Ticker	Company	Δ Shares	Shares	Value
TVTX	Travere Therapeutics, Inc.	+701,115	2,179,069	$123,792,909
MMED	MiniMed Group, Inc.	+465,000	1,520,000	$22,724,000
ERAS	Erasca, Inc.	+298,681	1,402,150	$25,687,388
CMPX	Compass Therapeutics, Inc.	+219,621	3,524,929	$7,719,594
CYTK	Cytokinetics Inc	+142,616	187,980	$16,014,016
INSP	Inspire Medical Systems, Inc.	+112,200	244,000	$10,884,840
PHR	Phreesia, Inc.	+96,500	696,900	$7,171,101
TNGX	Tango Therapeutics, Inc.	+69,636	456,551	$14,271,784
OLMA	Olema Pharmaceuticals, Inc.	+64,800	235,178	$2,942,076
TARS	Tarsus Pharmaceuticals, Inc.	+51,908	277,087	$17,439,855
CLDX	Celldex Therapeutics, Inc.	+48,876	699,146	$26,015,222
INSM	INSMED Inc	+47,850	362,150	$38,612,433
BCAX	Bicara Therapeutics Inc.	+46,191	535,286	$15,892,641
INDV	Indivior Pharmaceuticals, Inc.	+45,500	245,500	$10,072,865
MLYS	Mineralys Therapeutics, Inc.	+45,200	484,951	$13,083,977
CORT	Corcept Therapeutics Inc	+21,750	72,000	$6,260,400
BBIO	BridgeBio Pharma, Inc.	+16,500	144,750	$10,780,980
ALKS	Alkermes plc.	+15,825	199,811	$10,470,096
DHR	Danaher Corp	+14,800	76,300	$14,533,624
SYK	Stryker Corp	+14,200	29,000	$9,130,360
TEVA	Teva Pharmaceutical Industries Ltd	+13,500	59,000	$1,998,920
BSX	Boston Scientific Corp	+13,200	528,500	$22,556,380
UNH	Unitedhealth Group Inc	+10,750	63,750	$26,496,412
MBX	MBX Biosciences, Inc.	+10,251	298,218	$16,461,633
ATEC	Alphatec Holdings, Inc.	+10,000	360,000	$3,114,000
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
ELVN	Enliven Therapeutics, Inc.	−361,875	464,625	$23,579,718
AGIO	Agios Pharmaceuticals, Inc.	−266,600	532,563	$19,763,412
RARE	Ultragenyx Pharmaceutical Inc.	−250,918	967,855	$32,316,678
EVH	Evolent Health, Inc.	−175,000	2,500,000	$13,550,000
OMDA	Omada Health, Inc.	−168,000	373,000	$8,187,350
AZTA	Azenta, Inc.	−166,100	403,000	$10,284,560
ACRS	Aclaris Therapeutics, Inc.	−142,118	4,330,532	$22,908,514
SGRY	Surgery Partners, Inc.	−124,000	84,000	$1,411,200
COGT	Cogent Biosciences, Inc.	−108,238	515,917	$19,965,987
RVMD	Revolution Medicines, Inc.	−104,255	1,105,210	$206,983,728
XENE	Xenon Pharmaceuticals Inc.	−79,113	683,907	$41,280,626
VERA	Vera Therapeutics, Inc.	−76,001	427,584	$18,347,629
CAI	Caris Life Sciences, Inc.	−75,500	487,500	$8,687,250
VKTX	Viking Therapeutics, Inc.	−70,500	25,500	$994,755
ARDX	Ardelyx, Inc.	−57,704	2,241,769	$11,433,021
MLTX	MoonLake Immunotherapeutics	−51,004	10,696	$208,251
ARGX	Argenx SE	−45,750	52,750	$48,939,867
KYMR	Kymera Therapeutics, Inc.	−43,715	453,156	$51,963,398
DYN	Dyne Therapeutics, Inc.	−30,044	942,154	$20,925,240
NVO	Novo Nordisk A S	−26,500	63,500	$3,044,190
ASND	Ascendis Pharma A/S	−25,250	168,750	$45,009,000
SRRK	Scholar Rock Holding Corp	−24,364	715,452	$39,349,860
MIRM	Mirum Pharmaceuticals, Inc.	−13,149	798,145	$93,438,835
DXCM	Dexcom Inc	−12,600	343,000	$23,101,050
ALNY	Alnylam Pharmaceuticals, Inc.	−7,250	66,750	$20,093,752
No positions match the current search.

New Positions

Positions the filer opened this quarter

16 positions

Ticker	Company	Shares	Value
AVLN	Avalyn Pharma Inc.	662,918	$21,823,260
COAG	Hemab Therapeutics Holdings, Inc.	575,432	$21,135,617
PBLS	Parabilis Medicines, Inc.	578,028	$15,820,626
OMER	Omeros Corp	718,499	$6,832,925
DFTX	Definium Therapeutics, Inc.	143,187	$6,735,516
MOBI	Mobia Medical, Inc.	418,200	$5,603,880
TRVI	Trevi Therapeutics, Inc.	260,000	$4,849,000
SYRE	Spyre Therapeutics, Inc.	42,254	$3,751,310
NGEN	Nervgen Pharma Corp.	1,208,231	$2,488,955
MDT	Medtronic plc	30,900	$2,417,307
SGMT	Sagimet Biosciences Inc.	250,000	$1,932,500
CAPR	Capricor Therapeutics, Inc.	74,448	$1,792,707
ALT	Altimmune, Inc.	471,465	$1,433,253
KLRA	Kailera Therapeutics, Inc.	65,000	$1,431,950
AXSM	Axsome Therapeutics, Inc.	5,500	$1,346,235
GKOS	GLAUKOS Corp	4,750	$663,860
No positions match the current search.

Sold Out

Positions the filer fully exited

12 positions

Ticker	Company	Shares	Value
—		169,859	$19,503,210
CNTA	Centessa Pharmaceuticals plc	351,828	$13,974,608
—		257,253	$8,612,830
REGN	Regeneron Pharmaceuticals, Inc.	10,100	$7,803,664
—		162,750	$6,547,433
—		113,748	$5,996,795
XBI	State Street(R) SPDR(R) S&P(R) Biotech ETF	30,000	$3,831,900
EW	Edwards Lifesciences Corp	28,900	$2,314,312
ACHC	Acadia Healthcare Company, Inc.	75,500	$1,765,945
JAZZ	Jazz Pharmaceuticals plc	5,750	$1,087,037
GOSS	Gossamer Bio, Inc.	1,609,492	$529,522
—		21,062	$304,557
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

104 tracked positions · $2,048,809,888 total · filing declares 104 positions · $2,048,808,191 · as of Jun 30, 2026

All sectors Healthcare

Showing 1–50 of 104 positions by value · page 1 of 3

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	Held (qtrs)	Est. cost/share	% of Portfolio
RVMD	Revolution Medicines, Inc. Healthcare	Reduced	1,105,210	-104,255	$206,983,728	+76.0%	14	$31.90	10.10%
TVTX	Travere Therapeutics, Inc. Healthcare	Added	2,179,069	+701,115	$123,792,909	+181.9%	23	$23.94	6.04%
LLY	ELI LILLY & Co Healthcare	Held	98,700	0	$118,383,750	+30.4%	11	$692.11	5.78%
MDGL	Madrigal Pharmaceuticals, Inc. Healthcare	Added	174,999	+4,000	$93,965,713	+5.0%	26+	before history	4.59%
MIRM	Mirum Pharmaceuticals, Inc. Healthcare	Reduced	798,145	-13,149	$93,438,835	+24.7%	26+	before history	4.56%
RYTM	Rhythm Pharmaceuticals, Inc. Healthcare	Added	692,598	+2,850	$76,899,155	+28.2%	26+	before history	3.75%
KYMR	Kymera Therapeutics, Inc. Healthcare	Reduced	453,156	-43,715	$51,963,398	+25.6%	24	$34.35	2.54%
ARGX	Argenx SE Healthcare	Reduced	52,750	-45,750	$48,939,867	−32.0%	26+	before history	2.39%
ASND	Ascendis Pharma A/S Healthcare	Reduced	168,750	-25,250	$45,009,000	+1.4%	26+	before history	2.20%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Reduced	683,907	-79,113	$41,280,626	−7.0%	26+	before history	2.01%
SRRK	Scholar Rock Holding Corp Healthcare	Reduced	715,452	-24,364	$39,349,860	+8.2%	7	$32.95	1.92%
INSM	INSMED Inc Healthcare	Added	362,150	+47,850	$38,612,433	−24.9%	9	$50.23	1.88%
PEN	Penumbra Inc Healthcare	Reduced	115,750	-4,750	$36,548,062	−7.6%	26+	before history	1.78%
GPCR	Structure Therapeutics Inc. Healthcare	Added	640,317	+100	$34,365,813	+11.4%	11	$44.26	1.68%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	Reduced	967,855	-250,918	$32,316,678	+26.6%	26+	before history	1.58%
IRTC	iRhythm Holdings, Inc. Healthcare	Added	269,650	+7,900	$32,074,867	+3.8%	26+	before history	1.57%
ISRG	Intuitive Surgical Inc Healthcare	Reduced	76,460	-5,540	$30,406,612	−19.6%	26+	before history	1.48%
AGL	agilon health, inc. Healthcare	Added	262,600	+2,600	$28,145,468	+1268.5%	21	unpriced	1.37%
UNH	Unitedhealth Group Inc Healthcare	Added	63,750	+10,750	$26,496,412	+84.8%	3	$336.38	1.29%
CLDX	Celldex Therapeutics, Inc. Healthcare	Added	699,146	+48,876	$26,015,222	+26.1%	18	$32.61	1.27%
ERAS	Erasca, Inc. Healthcare	Added	1,402,150	+298,681	$25,687,388	+43.9%	3	$6.23	1.25%
NBIX	Neurocrine Biosciences Inc Healthcare	Reduced	144,750	-5,700	$24,396,165	+23.1%	26+	before history	1.19%
ELVN	Enliven Therapeutics, Inc. Healthcare	Reduced	464,625	-361,875	$23,579,718	−27.2%	10	$17.66	1.15%
THC	Tenet Healthcare Corp Healthcare	Held	125,000	0	$23,385,000	−0.9%	7	$148.59	1.14%
DXCM	Dexcom Inc Healthcare	Reduced	343,000	-12,600	$23,101,050	+3.4%	22	unpriced	1.13%
ACRS	Aclaris Therapeutics, Inc. Healthcare	Reduced	4,330,532	-142,118	$22,908,514	+36.6%	26+	before history	1.12%
MMED	MiniMed Group, Inc. Healthcare	Added	1,520,000	+465,000	$22,724,000	+44.4%	2	unpriced	1.11%
BSX	Boston Scientific Corp Healthcare	Added	528,500	+13,200	$22,556,380	−30.2%	13	$69.60	1.10%
PHVS	Pharvaris N.V. Healthcare	Added	648,333	+2,800	$22,419,355	+22.9%	10	$26.42	1.09%
AVLN	Avalyn Pharma Inc. Healthcare	NEW	662,918	NEW	$21,823,260	NEW	1	$28.86	1.07%
COAG	Hemab Therapeutics Holdings, Inc. Healthcare	NEW	575,432	NEW	$21,135,617	NEW	1	$27.59	1.03%
DYN	Dyne Therapeutics, Inc. Healthcare	Reduced	942,154	-30,044	$20,925,240	+18.7%	10	$18.21	1.02%
ALNY	Alnylam Pharmaceuticals, Inc. Healthcare	Reduced	66,750	-7,250	$20,093,752	−17.9%	26+	before history	0.98%
COGT	Cogent Biosciences, Inc. Healthcare	Reduced	515,917	-108,238	$19,965,987	−16.9%	5	$6.84	0.97%
AGIO	Agios Pharmaceuticals, Inc. Healthcare	Reduced	532,563	-266,600	$19,763,412	−26.9%	26+	before history	0.96%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	Reduced	582,744	-6,050	$19,749,194	+4.8%	8	$20.56	0.96%
VERA	Vera Therapeutics, Inc. Healthcare	Reduced	427,584	-76,001	$18,347,629	−9.4%	10	$35.12	0.90%
TARS	Tarsus Pharmaceuticals, Inc. Healthcare	Added	277,087	+51,908	$17,439,855	+10.4%	7	$50.99	0.85%
HTFL	Heartflow, Inc. Healthcare	Added	573,500	+1,000	$16,826,490	+20.8%	4	$29.62	0.82%
MBX	MBX Biosciences, Inc. Healthcare	Added	298,218	+10,251	$16,461,633	+91.5%	4	$14.48	0.80%
CYTK	Cytokinetics Inc Healthcare	Added	187,980	+142,616	$16,014,016	+435.6%	3	$69.56	0.78%
BCAX	Bicara Therapeutics Inc. Healthcare	Added	535,286	+46,191	$15,892,641	+63.4%	8	unpriced	0.78%
PBLS	Parabilis Medicines, Inc. Healthcare	NEW	578,028	NEW	$15,820,626	NEW	1	unpriced	0.77%
ZLAB	Zai Lab Ltd Healthcare	Held	814,707	0	$15,479,433	+1.0%	26+	before history	0.76%
DHR	Danaher Corp Healthcare	Added	76,300	+14,800	$14,533,624	+24.6%	6	$210.50	0.71%
TNGX	Tango Therapeutics, Inc. Healthcare	Added	456,551	+69,636	$14,271,784	+76.3%	3	$11.07	0.70%
EVH	Evolent Health, Inc. Healthcare	Reduced	2,500,000	-175,000	$13,550,000	+122.2%	22	$20.53	0.66%
PTCT	Ptc Therapeutics, Inc. Healthcare	Added	162,298	+500	$13,238,647	+20.1%	3	$71.53	0.65%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Added	484,951	+45,200	$13,083,977	+9.8%	6	$16.34	0.64%
ZBIO	Zenas BioPharma, Inc. Healthcare	Held	502,077	0	$12,742,714	+29.8%	8	unpriced	0.62%

Showing the top 50 of 104 positions. Create a free account to see every position, past quarters, search, filters and CSV export.

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.