Rock Springs Capital Management LP

CIK

1595725

Location

Baltimore, MD

Portfolio Value

Mid $2,048,809,888

Diversification

Diversified

Filing Date

Global Rank

#1,317 / 8,700 ▲ 314

Top Industry

Biotechnology 73.3%

Period ended 2 months ago

Filed Aug 14, 2026 · 29d

26 quarters · since Mar 2020

Portfolio Concentration

104 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

10.1%

+2.9 pts

Top 5

31.1%

+4.0 pts

Top 10

44.0%

+2.0 pts

HHI

305

Diversified+34

Portfolio Trend

26 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$2,048,809,888	104

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

25 positions

Ticker	Company	Δ Shares	Shares	Value
TVTX	Travere Therapeutics, Inc.	+701,115	2,179,069	$123,792,909
MMED	MiniMed Group, Inc.	+465,000	1,520,000	$22,724,000
ERAS	Erasca, Inc.	+298,681	1,402,150	$25,687,388
CMPX	Compass Therapeutics, Inc.	+219,621	3,524,929	$7,719,594
CYTK	Cytokinetics Inc	+142,616	187,980	$16,014,016
INSP	Inspire Medical Systems, Inc.	+112,200	244,000	$10,884,840
PHR	Phreesia, Inc.	+96,500	696,900	$7,171,101
TNGX	Tango Therapeutics, Inc.	+69,636	456,551	$14,271,784
OLMA	Olema Pharmaceuticals, Inc.	+64,800	235,178	$2,942,076
TARS	Tarsus Pharmaceuticals, Inc.	+51,908	277,087	$17,439,855
CLDX	Celldex Therapeutics, Inc.	+48,876	699,146	$26,015,222
INSM	INSMED Inc	+47,850	362,150	$38,612,433
BCAX	Bicara Therapeutics Inc.	+46,191	535,286	$15,892,641
INDV	Indivior Pharmaceuticals, Inc.	+45,500	245,500	$10,072,865
MLYS	Mineralys Therapeutics, Inc.	+45,200	484,951	$13,083,977
CORT	Corcept Therapeutics Inc	+21,750	72,000	$6,260,400
BBIO	BridgeBio Pharma, Inc.	+16,500	144,750	$10,780,980
ALKS	Alkermes plc.	+15,825	199,811	$10,470,096
DHR	Danaher Corp /De/	+14,800	76,300	$14,533,624
SYK	Stryker Corp	+14,200	29,000	$9,130,360
TEVA	Teva Pharmaceutical Industries Ltd	+13,500	59,000	$1,998,920
BSX	Boston Scientific Corp	+13,200	528,500	$22,556,380
UNH	Unitedhealth Group Inc	+10,750	63,750	$26,496,412
MBX	MBX Biosciences, Inc.	+10,251	298,218	$16,461,633
ATEC	Alphatec Holdings, Inc.	+10,000	360,000	$3,114,000
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
ELVN	Enliven Therapeutics, Inc.	−361,875	464,625	$23,579,718
AGIO	Agios Pharmaceuticals, Inc.	−266,600	532,563	$19,763,412
RARE	Ultragenyx Pharmaceutical Inc.	−250,918	967,855	$32,316,678
EVH	Evolent Health, Inc.	−175,000	2,500,000	$13,550,000
OMDA	Omada Health, Inc.	−168,000	373,000	$8,187,350
AZTA	Azenta, Inc.	−166,100	403,000	$10,284,560
ACRS	Aclaris Therapeutics, Inc.	−142,118	4,330,532	$22,908,514
SGRY	Surgery Partners, Inc.	−124,000	84,000	$1,411,200
COGT	Cogent Biosciences, Inc.	−108,238	515,917	$19,965,987
RVMD	Revolution Medicines, Inc.	−104,255	1,105,210	$206,983,728
XENE	Xenon Pharmaceuticals Inc.	−79,113	683,907	$41,280,626
VERA	Vera Therapeutics, Inc.	−76,001	427,584	$18,347,629
CAI	Caris Life Sciences, Inc.	−75,500	487,500	$8,687,250
VKTX	Viking Therapeutics, Inc.	−70,500	25,500	$994,755
ARDX	Ardelyx, Inc.	−57,704	2,241,769	$11,433,021
MLTX	MoonLake Immunotherapeutics	−51,004	10,696	$208,251
ARGX	Argenx SE	−45,750	52,750	$48,939,867
KYMR	Kymera Therapeutics, Inc.	−43,715	453,156	$51,963,398
DYN	Dyne Therapeutics, Inc.	−30,044	942,154	$20,925,240
NVO	Novo Nordisk A S	−26,500	63,500	$3,044,190
ASND	Ascendis Pharma A/S	−25,250	168,750	$45,009,000
SRRK	Scholar Rock Holding Corp	−24,364	715,452	$39,349,860
MIRM	Mirum Pharmaceuticals, Inc.	−13,149	798,145	$93,438,835
DXCM	Dexcom Inc	−12,600	343,000	$23,101,050
ALNY	Alnylam Pharmaceuticals, Inc.	−7,250	66,750	$20,093,752
No positions match the current search.

New Positions

Positions the filer opened this quarter

16 positions

Ticker	Company	Shares	Value
AVLN	Avalyn Pharma Inc.	662,918	$21,823,260
COAG	Hemab Therapeutics Holdings, Inc.	575,432	$21,135,617
PBLS	Parabilis Medicines, Inc.	578,028	$15,820,626
OMER	Omeros Corp	718,499	$6,832,925
DFTX	Definium Therapeutics, Inc.	143,187	$6,735,516
MOBI	Mobia Medical, Inc.	418,200	$5,603,880
TRVI	Trevi Therapeutics, Inc.	260,000	$4,849,000
SYRE	Spyre Therapeutics, Inc.	42,254	$3,751,310
NGEN	Nervgen Pharma Corp.	1,208,231	$2,488,955
MDT	Medtronic plc	30,900	$2,417,307
SGMT	Sagimet Biosciences Inc.	250,000	$1,932,500
CAPR	Capricor Therapeutics, Inc.	74,448	$1,792,707
ALT	Altimmune, Inc.	471,465	$1,433,253
KLRA	Kailera Therapeutics, Inc.	65,000	$1,431,950
AXSM	Axsome Therapeutics, Inc.	5,500	$1,346,235
GKOS	GLAUKOS Corp	4,750	$663,860
No positions match the current search.

Sold Out

Positions the filer fully exited

12 positions

Ticker	Company	Shares	Value
REGN	Regeneron Pharmaceuticals, Inc.	10,100	$7,803,664
BWX	State Street SPDR Bloomberg International Treasury Bond ETF	30,000	$3,831,900
EW	Edwards Lifesciences Corp	28,900	$2,314,312
ACHC	Acadia Healthcare Company, Inc.	75,500	$1,765,945
JAZZ	Jazz Pharmaceuticals plc	5,750	$1,087,037
GOSS	Gossamer Bio, Inc.	1,609,492	$529,522
—		162,750	$0
—		169,859	$0
—		257,253	$0
—		113,748	$0
—		21,062	$0
CNTA	Centessa Pharmaceuticals plc	351,828	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

104 tracked positions · $2,048,809,888 total · filing declares 104 positions · $2,048,808,191 · as of Jun 30, 2026

All sectors Healthcare

Showing 1–50 of 104 positions by value · page 1 of 3

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
RVMD	Revolution Medicines, Inc. Healthcare	Reduced	1,105,210	-104,255	$206,983,728	+76.0%	10.10%
TVTX	Travere Therapeutics, Inc. Healthcare	Added	2,179,069	+701,115	$123,792,909	+181.9%	6.04%
LLY	ELI LILLY & Co Healthcare	Held	98,700	0	$118,383,750	+30.4%	5.78%
MDGL	Madrigal Pharmaceuticals, Inc. Healthcare	Added	174,999	+4,000	$93,965,713	+5.0%	4.59%
MIRM	Mirum Pharmaceuticals, Inc. Healthcare	Reduced	798,145	-13,149	$93,438,835	+24.7%	4.56%
RYTM	Rhythm Pharmaceuticals, Inc. Healthcare	Added	692,598	+2,850	$76,899,155	+28.2%	3.75%
KYMR	Kymera Therapeutics, Inc. Healthcare	Reduced	453,156	-43,715	$51,963,398	+25.6%	2.54%
ARGX	Argenx SE Healthcare	Reduced	52,750	-45,750	$48,939,867	−32.0%	2.39%
ASND	Ascendis Pharma A/S Healthcare	Reduced	168,750	-25,250	$45,009,000	+1.4%	2.20%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Reduced	683,907	-79,113	$41,280,626	−7.0%	2.01%
SRRK	Scholar Rock Holding Corp Healthcare	Reduced	715,452	-24,364	$39,349,860	+8.2%	1.92%
INSM	INSMED Inc Healthcare	Added	362,150	+47,850	$38,612,433	−24.9%	1.88%
PEN	Penumbra Inc Healthcare	Reduced	115,750	-4,750	$36,548,062	−7.6%	1.78%
GPCR	Structure Therapeutics Inc. Healthcare	Added	640,317	+100	$34,365,813	+11.4%	1.68%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	Reduced	967,855	-250,918	$32,316,678	+26.6%	1.58%
IRTC	iRhythm Holdings, Inc. Healthcare	Added	269,650	+7,900	$32,074,867	+3.8%	1.57%
ISRG	Intuitive Surgical Inc Healthcare	Reduced	76,460	-5,540	$30,406,612	−19.6%	1.48%
AGL	agilon health, inc. Healthcare	Added	262,600	+2,600	$28,145,468	+1268.5%	1.37%
UNH	Unitedhealth Group Inc Healthcare	Added	63,750	+10,750	$26,496,412	+84.8%	1.29%
CLDX	Celldex Therapeutics, Inc. Healthcare	Added	699,146	+48,876	$26,015,222	+26.1%	1.27%
ERAS	Erasca, Inc. Healthcare	Added	1,402,150	+298,681	$25,687,388	+43.9%	1.25%
NBIX	Neurocrine Biosciences Inc Healthcare	Reduced	144,750	-5,700	$24,396,165	+23.1%	1.19%
ELVN	Enliven Therapeutics, Inc. Healthcare	Reduced	464,625	-361,875	$23,579,718	−27.2%	1.15%
THC	Tenet Healthcare Corp Healthcare	Held	125,000	0	$23,385,000	−0.9%	1.14%
DXCM	Dexcom Inc Healthcare	Reduced	343,000	-12,600	$23,101,050	+3.4%	1.13%
ACRS	Aclaris Therapeutics, Inc. Healthcare	Reduced	4,330,532	-142,118	$22,908,514	+36.6%	1.12%
MMED	MiniMed Group, Inc. Healthcare	Added	1,520,000	+465,000	$22,724,000	+44.4%	1.11%
BSX	Boston Scientific Corp Healthcare	Added	528,500	+13,200	$22,556,380	−30.2%	1.10%
PHVS	Pharvaris N.V. Healthcare	Added	648,333	+2,800	$22,419,355	+22.9%	1.09%
AVLN	Avalyn Pharma Inc. Healthcare	NEW	662,918	NEW	$21,823,260	NEW	1.07%
COAG	Hemab Therapeutics Holdings, Inc. Healthcare	NEW	575,432	NEW	$21,135,617	NEW	1.03%
DYN	Dyne Therapeutics, Inc. Healthcare	Reduced	942,154	-30,044	$20,925,240	+18.7%	1.02%
ALNY	Alnylam Pharmaceuticals, Inc. Healthcare	Reduced	66,750	-7,250	$20,093,752	−17.9%	0.98%
COGT	Cogent Biosciences, Inc. Healthcare	Reduced	515,917	-108,238	$19,965,987	−16.9%	0.97%
AGIO	Agios Pharmaceuticals, Inc. Healthcare	Reduced	532,563	-266,600	$19,763,412	−26.9%	0.96%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	Reduced	582,744	-6,050	$19,749,194	+4.8%	0.96%
VERA	Vera Therapeutics, Inc. Healthcare	Reduced	427,584	-76,001	$18,347,629	−9.4%	0.90%
TARS	Tarsus Pharmaceuticals, Inc. Healthcare	Added	277,087	+51,908	$17,439,855	+10.4%	0.85%
HTFL	Heartflow, Inc. Healthcare	Added	573,500	+1,000	$16,826,490	+20.8%	0.82%
MBX	MBX Biosciences, Inc. Healthcare	Added	298,218	+10,251	$16,461,633	+91.5%	0.80%
CYTK	Cytokinetics Inc Healthcare	Added	187,980	+142,616	$16,014,016	+435.6%	0.78%
BCAX	Bicara Therapeutics Inc. Healthcare	Added	535,286	+46,191	$15,892,641	+63.4%	0.78%
PBLS	Parabilis Medicines, Inc. Healthcare	NEW	578,028	NEW	$15,820,626	NEW	0.77%
ZLAB	Zai Lab Ltd Healthcare	Held	814,707	0	$15,479,433	+1.0%	0.76%
DHR	Danaher Corp /De/ Healthcare	Added	76,300	+14,800	$14,533,624	+24.6%	0.71%
TNGX	Tango Therapeutics, Inc. Healthcare	Added	456,551	+69,636	$14,271,784	+76.3%	0.70%
EVH	Evolent Health, Inc. Healthcare	Reduced	2,500,000	-175,000	$13,550,000	+122.2%	0.66%
PTCT	Ptc Therapeutics, Inc. Healthcare	Added	162,298	+500	$13,238,647	+20.1%	0.65%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Added	484,951	+45,200	$13,083,977	+9.8%	0.64%
ZBIO	Zenas BioPharma, Inc. Healthcare	Held	502,077	0	$12,742,714	+29.8%	0.62%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.