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SRPT · Sarepta Therapeutics, Inc.

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$16.07 +0.06 (+0.37%) At close · Nov 13
Market Cap
$1.72B
Shares
107.24M
Volume · Nov 13 1.33M Avg daily vol (3M) 2.72M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$16.07 Open$16.05 Day$15.70–16.23 52W close$14.86–23.83 Avg vol 30d2.5M Short int19.3M · 18.0% of shares · 7.8d Short vol50% Last earningsNov 5, 2026 DataJan 2020–Nov 2026 Filing10-Q · Nov 5

Up next

Feb 24, 2027 Est · unconfirmed · in 14 wks

Latest documents

2026
Nov 9
Investor event
DM1 and FSHD registrational studies expected within 12 months

Sarepta expects DM1 and FSHD programs to enter registrational studies within 12 months, with potential for accelerated approval, while Huntington's proof of biologic activity is anticipated around the middle of next year.

3 source passages
if you think about where we could be 12 months from now, I would expect they would have both DM1 and FSHD in registrational studies with the potential for accelerated approval, so approval not too far out on the horizon. We would expect to have proof of biology of our Huntington's program. somewhere around the middle of next year is when we'd expect proof of biologic activity. Open the document at this passage
Nov 5
Earnings call
Revenue guidance raised as siRNA pivotal preparations advance

Sarepta Therapeutics raised 2026 total net product revenue guidance to $1.25 to $1.3 billion, citing stabilized Elevitus demand and strong PMO performance. The company also plans to share multiple-dose data for its DM1 and FSHD programs and prepare registrational studies.

Read from the first part of this long document
5 source passages
Based on our strong PMO performance and stabilization in Elevitus, we are raising the low end of our 2026 total net product revenue guidance and narrowing the range to $1.25 to $1.3 billion. We intend to remain rigorous about where we invest, prioritizing programs where we believe Sarepta has a scientific or commercial advantage, and maintaining discipline across the broader cost structure. More specifically, our key intended differentiators for the DM1 and FSHD programs include reaching enough muscle fibers, achieving sufficient intracellular exposure, and driving meaningful target knockdowns. Our multiple ascending-dose datasets, which we expect to share in the upcoming weeks, are designed to provide the data necessary to move both programs into late-stage development. Given this potential, we are actively preparing for our registrational studies for both programs. Open the document at this passage
Nov 5
Current report 8-K
Guidance raised as product revenue reaches $323.8 million

Sarepta Therapeutics reported net product revenues of approximately $323.8 million, raised full-year product-revenue guidance to $1.25 billion to $1.3 billion, and expects SRP-1003 and SRP-1001 multiple-ascending-dose data in the fourth quarter of 2026.

Financial results Read from the first part of this long document
3 source passages
Net product revenues for the third quarter 2026 totaled approximately $323.8 million, consisting of approximately $240.3 million of PMO net product revenues and $83.5 million of ELEVIDYS® net product revenue The Company expects the PMO franchise to remain strong and is updating its full-year guidance ranges, raising the low end of total net product revenue guidance by $50.0 million to a range of $1.25 billion to $1.3 billion. Multiple ascending dose data from SRP-1003 and SRP-1001 are expected in the fourth quarter of 2026, providing important insights including DMPK knockdown and splicing correction in DM1 and DUX4 knockdown in FSHD. Sarepta is actively preparing for Phase 3 development in both programs Open the document at this passage
Nov 5
Quarterly report 10-Q FY2026 Q3, ended Sep 30
Nine-month net income swings to positive

Sarepta Therapeutics reported nine-month net income of $297,608 thousand versus a $301,184 thousand loss, while collaboration and other revenue reached $530,438 thousand.

Revenue $381.35M ▼ 4.5% Net loss $28.46M Diluted EPS -$0.27
Read from the MD&A section
4 source passages
The purpose of Management's Discussion and Analysis of Financial Condition and Results of Operations is to provide an understanding of the financial condition, changes in financial condition and results of operations of Sarepta Therapeutics, Inc. *All values are in US Dollars. | Net income (loss) | 297,608 | (301,184) | 598,792 | * | | | Collaboration and other | 530,438 | 260,614 | 269,824 | | 104% | Open the document at this passage
Sep 23
Current report 8-K
Entered into a material agreement

Sarepta Therapeutics, Inc. entered a settlement on September 23, 2026 with REGENXBIO, UPenn and Catalent resolving patent litigation, requiring Sarepta to pay REGENXBIO $39.0 million and securing patent non-suit commitments covering ELEVIDYS and AAVrh74-based gene therapy products.

All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$1.96B
Trailing 12 months
Net income (TTM)
−$114.62M
Trailing 12 months
Revenue growth YoY
-4.5%
Year over year
Operating margin
-2.5%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
10.2%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$21.41M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+5.7%
Year over year · more shares
Price change (1Y)
-9.8%
Trailing year
Short interest
18.0%
Latest settlement · 7.8 days to cover
View all 125 metrics

AI Brief

Q2 FY26 earnings call · Aug 5, 2026
Q2 FY26

TL;DR. Sarepta delivered Q2 GAAP and non-GAAP operating profitability on $328.7M in net product revenue, narrowed 2026 net product revenue guidance to $1.2–$1.3B (toward the low end) and tightened non-GAAP opex to $800–$850M, while raising collaboration/other revenue guidance by $75M at the midpoint; FDA accepted sNDAs for Elevidys/Amondys 45 and Vyondys 53 conversion to traditional approval, and DM1/FSHD MAD readouts remain on track for 2H 2026 with Elevidys Cohort 8 full enrollment by year-end and 12-week data in Q1 2027.

Bullish
  • + Sarepta posted Q2 GAAP operating income of $13.3M and non-GAAP operating income of $86.5M, reflecting profitability.
  • + Cash and investments grew ~$197M sequentially to ~$945M, strengthening the balance sheet.
  • + Raised 2026 collaboration and other revenue guidance by $75M at the midpoint to $550–$600M.
  • + Tightened 2026 non-GAAP opex guidance lower to $800–$850M, the low end of prior range.
  • + FDA accepted sNDAs seeking conversion of Elevidys 45 and Vyondys 53 to traditional approval.
  • + DM1 and FSHD siRNA MAD readouts remain on track for 2H 2026, with Huntington's Phase 1 dosing underway.
Bearish
  • − 2026 total net product revenue guidance narrowed to $1.2–$1.3B, implying results toward the low end of prior range.
  • − Company expects 2H 2026 Elevidys revenue to be modestly lower than 1H, with Q3 specifically trending below Q2.
  • − Future PMO franchise competition risk flagged, with potential Exon 51 skipper market entry.

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Strong Sell Momentum Very Weak Sentiment Neutral Fundamentals Fair Quant / Vol Very High
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Strong Sell
50 / 200-day cross No cross
Price vs 200-day avg −13%
below
Price vs 50-day avg −14%
below
RSI (14) 37
neutral
MACD trend Negative
52-week position 13%
near low
Momentum
relative strength
Very Weak
1-month return −6%
trailing
6-month return −4%
trailing
YTD return −25%
this year
Relative strength −4%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $19 › 200d $19 — 50d above 200d
Institutional flow Distributing
265 of 333 funds reported for Sep 30 · net -5.0M sh shares · +21 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
18.00% of shares out · ▼ -13.6% MoM · 7.8 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr low
333 holders — near 3-yr low, contrarian setup
Squeeze score 61
elevated · 0–100
Fundamentals
Fair
Revenue growth +16%
Y/Y
EPS growth −405%
Y/Y
Free cash flow $-307.5M
Buyback $475.0M
remaining
Balance sheet $27.7M
net debt
Quant / Vol
risk profile
Very High
Volatility 71%
annualized · 1-yr
Max drawdown −38%
past year
ATR 5.8%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the 8-K filed Nov 5, 2026
Total net product revenue · full-year Raised $1.25B – $1.3B
Aug 5, 2026 $1.2B – $1.3B changed to Nov 5, 2026 $1.25B – $1.3B
prior FY $2.2B midpoint −42.0% Y/Y
Combined non-GAAP R&D and SG&A expenses · full-year Non-GAAP Lowered $800M – $825M
May 6, 2026 $800M – $900M changed to Nov 5, 2026 $800M – $825M
Previous outlook earlier release · from the Earnings Call filed Aug 5, 2026

Still-open targets the latest release did not restate under the same label.

Total collaboration and other revenue · full year 2026 $550M – $600M
Non-GAAP OPEX · full year 2026 $800M – $850M
Guided vs delivered · last 1 settled
Full year 2021 net product revenue full year 2021
guided $605M – $615M
$701.89M Beat +15.1%

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Strong Sell
4 · 2 · 0
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−13% Bearish
Price vs 50-day avg
−14% Bearish
RSI (14)
37 Neutral
MACD trend
Negative Bearish
52-week position
13% Bearish
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $19 › 200d $19 — 50d above 200d
Institutional flow Distributing
265 of 333 funds reported for Sep 30 · net -5.0M sh shares · +21 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
18.00% of shares out · ▼ -13.6% MoM · 7.8 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr low
333 holders — near 3-yr low, contrarian setup
Price context
position in its 52-week range
Range low $15 Now $16 · 13% Range high $24
vs 200-day avg -13% vs 50-day avg -14%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SRPT
Sarepta Therapeutics, Inc.
this stock
$1.72B -25.3% +15.6% — 18.0%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Reducing
Holders
321
% held
100.7%
Reported
265 of 333
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
343
View
Short & Settlement
Short Interest Falling
Shares short
19.3M
Days to cover
7.8d
Change
-3.0M sh
View
Short Volume
Short vol %
50%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
632
Value
$11.1K
As of
Oct 2, 2026
View
Off-Exchange
Off-exchange %
41.6%
Week of
Oct 5, 2026
Off-exch Lit
View
Smart Money
Congressional Trades Sell
Member
Gilbert Cisneros
Amount
$1.0K–$15.0K
Traded
Apr 14, 2025
View
Financials
Financials
Revenue (FY)
$2.2B
Net income (FY)
$-713.4M
EPS diluted
$-7.13
View
Buybacks
Authorized
$500.0M
Remaining
$475.0M
Spent Remaining
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Nov 9, 2026
This year
21

Sarepta expects DM1 and FSHD programs to enter registrational studies within 12 months, with potential for accelerated approval, while Huntington's proof of biologic activity is anticipated around the middle of next year.

View
Proposed Sales
Value
$123.2K
Shares
7.2K
Filed
Mar 12, 2026
View
Exempt Offerings
Offering
$400.0M
Filed
Feb 28, 2020
View
Earnings & Events
Webcasts
Last webcast
Nov 9, 2026
View
Investor Relations
Latest news
Sarepta Therapeutics to Present a…
Published
Oct 26, 2026
View

Performance

5D 20D 120D MTD YTD
SRPT -9.8% -6.0% -3.6% -13.7% -25.3%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY -12.4% -4.9% -4.1% -13.5% -36.0%

Capital returns

Buyback program · as of Dec 31, 2025
Authorized
$500.00M
Spent (derived)
$25.00M
Remaining
$475.00M
Spent Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 873303 CUSIP 803607100 13F (30d) 247 filings 215 filers Visit website Investor relations