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COLL · Collegium Pharmaceutical, Inc

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$28.23 +0.08 (+0.28%) At close · Aug 14
Market Cap
$919.04M
Shares
32.56M
All earnings calls

Earnings call · FY2025 Q4

Collegium Pharmaceutical, Inc Q4 FY2025 Earnings Call

Collegium Pharmaceutical, Inc Q4 FY2025 Earnings Call

Concluded Feb 26, 2026 Audio replay
Feb 26, 2026 38:29 24 turns
Period
FY2025 Q4
Runtime
38:29
Sources
4 artifacts

Executive readout · one minute

What matters this quarter

Collegium delivered record full-year 2025 net revenues of $780.6 million (+24% YoY) and record adjusted EBITDA (+15% YoY), driven by Jornay PM net revenue of $148.9 million (+48% vs. pro forma 2024) and pain portfolio net revenues of $631.7 million (+6% YoY). The company reaffirmed full-year 2026 guidance, including Jornay PM revenue of $190–$200 million (>30% growth), and ended the year with $386.7 million in cash and a net leverage ratio under 1x.

Pain portfolio durability 56 Jornay PM growth 44 Capital deployment / business development 37 Authorized generic / Nucynta life cycle management 29 Financial performance / 2026 guidance 21 Balance sheet and leverage 19

Management tone

Confident

Net tone +78 · low hedging

Grounding quotes
  • “2025 was a year of transformative growth for Collegium Pharmaceutical, Inc. We delivered robust financial results due to strong commercial execution and deployed capital strategically to support long-term value creation.”
  • “In 2025, we achieved record top and bottom line results, growing full-year net revenues by 24% and adjusted EBITDA by 15%.”
  • “As reflected in our 2026 guidance, we expect Jornay revenue of $190 million-$200 million, representing more than 30% annual growth.”
  • “Our pain portfolio provides a strong financial foundation from which we continue to invest in our business. That foundation is bolstered by Jornay, a differentiated medicine with headroom for further meaningful growth”

Forward guidance

4 guided metrics

Management's latest ranges and targets are included below.

Research coverage

4 live sources

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Revenue $205.45M +12.9% YoY
Diluted EPS $0.46 +27.8% YoY
Gross margin 62.5% +8.5 pp YoY
Net income $16.96M +35.3% YoY

Research materials

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Key takeaways

What improved, and what deserves a closer read.

Constructive signals

  • Record FY 2025 net revenues of $780.6M, up 24% YoY, with record adjusted EBITDA up 15% YoY
  • Jornay PM FY 2025 net revenue of $148.9M, up 48% vs. pro forma 2024; Q4 Jornay PM revenue of $45.9M, up 57% YoY, with all-time-high prescriber count of 29,000 (+21% YoY)
  • Pain portfolio FY 2025 net revenues of $631.7M, up 6% YoY, with all three core pain medicines delivering full-year growth
  • Closed a $980M syndicated credit facility in December, improving interest rate and debt terms and adding flexibility for business development
  • Net leverage ratio below 1x, with more than $329M in cash from operations and $386.7M in cash, up ~$224M from end of 2024
  • 2026 Jornay PM guidance of $190M–$200M, representing more than 30% annual growth; reaffirmed full-year 2026 guidance

Risks & pressure points

  • Nucynta now facing authorized generic competition from Hikma (launched in January, with Nucynta ER AG expected in Q1 2026), introducing third-party generic pressure on the franchise
  • Company acknowledged uncertainty around future loss-of-exclusivity events for Xtampza and Belbuca, requiring continued field-force investment through those dates
  • Q4 total net revenues of $205.4M grew 13% YoY, a slower growth rate than the 24% full-year figure, suggesting deceleration in the quarter
  • Loss-of-exclusivity risk for the pain portfolio remains a stated uncertainty, with management noting they would pivot and moderate investment if an event occurs

Key moments

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“As reflected in our 2026 guidance, we expect Jornay revenue of $190 million-$200 million, representing more than 30% annual growth.” Vikram Karnani, CEO

Forward guidance

From the 8-K filed Feb 26, 2026.

Metric Guided
Product Revenues, Net table
full-year 2026
$805M – $825M
Jornay PM Revenue, Net table
full-year 2026
$190M – $200M
Adjusted EBITDA table
full-year 2026
$455M – $475M

Guidance from the call

Stated verbally and extracted from the transcript.

Metric Guided
Jornay revenue
2026
$190M – $200M
Full-screen source Call document