Ikarian Capital, LLC
Filing Date
Global Rank
#2,113
/ 8,700
▲ 50
Top Industry
Biotechnology
93.1%
Period ended 2 months ago
Filed Aug 14, 2026 · 30d
26 quarters · since Mar 2020
Portfolio Concentration
133 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
14.1%
+4.6 pts
Top 5
33.7%
+2.0 pts
Top 10
47.2%
+1.3 pts
HHI
386
Diversified+66
Portfolio Trend
26 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 99.8% | $870,117,470 |
| Financial Services | 0.2% | $1,760,107 |
| Technology | 0.0% | $6,776 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
21 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| PRQR | ProQR Therapeutics N.V. | +1,933,701 | 3,425,930 | $6,372,229 | |
| RZLT | Rezolute, Inc. | +918,533 | 935,012 | $4,862,062 | |
| CRDL | Cardiol Therapeutics Inc. | +600,000 | 3,325,000 | $3,524,500 | |
| ABVX | Abivax S.A. | +568,800 | 919,735 | $122,563,886 | |
| PALI | Palisade Bio, Inc. | +475,022 | 750,000 | $1,567,500 | |
| IONS | Ionis Pharmaceuticals Inc | +460,862 | 700,000 | $55,503,000 | |
| BHVN | Biohaven Ltd. | +335,700 | 748,181 | $11,132,933 | |
| PMN | ProMIS Neurosciences Inc. | +150,000 | 205,000 | $2,697,800 | |
| VERA | Vera Therapeutics, Inc. | +110,000 | 381,700 | $16,378,747 | |
| CNSP | CNS Pharmaceuticals, Inc. | +90,000 | 135,830 | $649,267 | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | +80,778 | 138,278 | $11,271,039 | |
| CAPR | Capricor Therapeutics, Inc. | +76,200 | 954,215 | $22,977,497 | |
| NXTC | NextCure, Inc. | +50,000 | 288,303 | $461,284 | |
| TECX | Tectonic Therapeutic, Inc. | +48,300 | 205,837 | $7,076,676 | |
| TENX | Tenax Therapeutics, Inc. | +45,300 | 1,177,200 | $17,128,260 | |
| ELVN | Enliven Therapeutics, Inc. | +42,841 | 126,541 | $6,421,955 | |
| PASG | Passage BIO, Inc. | +31,393 | 99,517 | $485,642 | |
| FTH | Faeth Therapeutics, Inc. | +29,035 | 35,386 | $884,650 | |
| ZURA | Zura Bio Ltd | +25,000 | 1,218,492 | $7,189,102 | |
| PRAX | Praxis Precision Medicines, Inc. | +22,161 | 93,742 | $31,383,884 | |
| CLDX | Celldex Therapeutics, Inc. | +17,253 | 592,500 | $22,046,925 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
25 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CNTB | Connect Biopharma Holdings Ltd | −994,552 | 4,538,534 | $10,801,710 | |
| CMPS | COMPASS Pathways plc | −660,000 | 15,000 | $212,250 | |
| OVID | Ovid Therapeutics Inc. | −625,000 | 2,269,704 | $6,105,503 | |
| IMUX | Immunic, Inc. | −607,198 | 67,464 | $1,036,921 | |
| OLMA | Olema Pharmaceuticals, Inc. | −564,800 | 583,281 | $7,296,845 | |
| RLMD | Relmada Therapeutics, Inc. | −540,000 | 2,148,359 | $14,866,644 | |
| AVTX | Avalo Therapeutics, Inc. | −469,817 | 90,183 | $1,666,581 | |
| BMY | Bristol Myers Squibb Co | −457,500 | 42,500 | $2,448,850 | |
| HROW | Harrow, Inc. | −407,272 | 135,775 | $5,766,364 | |
| EPRX | Eupraxia Pharmaceuticals Inc. | −405,000 | 809,741 | $5,352,388 | |
| RARE | Ultragenyx Pharmaceutical Inc. | −316,954 | 165,617 | $5,529,951 | |
| PEPG | PepGen Inc. | −300,000 | 447,165 | $804,897 | |
| IVA | Inventiva S.A. | −300,000 | 1,129,101 | $4,268,001 | |
| ALMS | Alumis Inc. | −251,300 | 1,226,848 | $34,523,502 | |
| DCTH | Delcath Systems, Inc. | −245,584 | 185,667 | $2,337,547 | |
| SLDB | Solid Biosciences Inc. | −221,453 | 42,956 | $429,130 | |
| ACOG | Alpha Cognition Inc. | −220,000 | 836,259 | $6,037,789 | |
| AVR | Anteris Technologies Global Corp. | −200,000 | 166,571 | $1,640,724 | |
| TRAW | Traws Pharma, Inc. | −200,000 | 478,142 | $401,639 | |
| CABA | Cabaletta Bio, Inc. | −200,000 | 700,000 | $2,177,000 | |
| PHVS | Pharvaris N.V. | −178,000 | 308,856 | $10,680,240 | |
| BBIO | BridgeBio Pharma, Inc. | −161,203 | 57,417 | $4,276,418 | |
| ANNX | Annexon, Inc. | −150,000 | 430,244 | $2,456,693 | |
| ANRO | Alto Neuroscience, Inc. | −107,662 | 407,338 | $10,749,649 | |
| ALEC | Alector, Inc. | −100,000 | 1,982,606 | $3,985,038 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| MRNA | Moderna, Inc. | 400,000 | $28,012,000 | |
| RCUS | Arcus Biosciences, Inc. | 504,559 | $15,555,553 | |
| COGT | Cogent Biosciences, Inc. | 370,084 | $14,322,250 | |
| CCCC | C4 Therapeutics, Inc. | 2,433,000 | $11,362,110 | |
| QTTB | Q32 Bio Inc. | 630,000 | $8,026,200 | |
| VRDN | Viridian Therapeutics, Inc.\DE | 425,000 | $7,807,250 | |
| HIMS | Hims & Hers Health, Inc. | 188,381 | $6,531,169 | |
| KZIA | Kazia Therapeutics Ltd | 396,201 | $5,578,510 | |
| SLS | SELLAS Life Sciences Group, Inc. | 354,700 | $5,235,372 | |
| BIOA | BioAge Labs, Inc. | 200,000 | $4,902,000 | |
| SION | Sionna Therapeutics, Inc. | 107,500 | $4,728,925 | |
| MNPR | Monopar Therapeutics | 47,861 | $4,431,449 | |
| ABSI | Absci Corp | 353,772 | $4,100,217 | |
| CLYM | Climb Bio, Inc. | 300,000 | $3,912,000 | |
| CUE | Cue Biopharma, Inc. | 104,364 | $3,293,727 | |
| RNTX | Rein Therapeutics, Inc. | 2,950,000 | $3,068,000 | |
| AMLX | Amylyx Pharmaceuticals, Inc. | 117,500 | $2,110,300 | |
| IRON | Disc Medicine, Inc. | 26,600 | $1,945,524 | |
| AMAN | Amanat Acquisition Corp. | 150,000 | $1,524,000 | |
| QNCX | Quince Therapeutics, Inc. | 72,251 | $1,314,245 | |
| IMNM | Immunome Inc. | 60,000 | $1,271,400 | |
| ELTX | Elicio Therapeutics, Inc. | 314,200 | $1,228,522 | |
| PLRX | Pliant Therapeutics, Inc. | 1,000,000 | $1,140,000 | |
| TRAX | First Tracks Biotherapeutics, Inc. | 42,775 | $860,633 | |
| INM | InMed Pharmaceuticals Inc. | 245,025 | $379,788 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
25 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| BWX | State Street SPDR Bloomberg International Treasury Bond ETF | 800,000 | $102,184,000 | |
| CYTK | Cytokinetics Inc | 1,242,472 | $81,891,329 | |
| QQQ | Invesco Qqq Trust, Series 1 | 100,000 | $57,718,000 | |
| AAXJ | iShares MSCI All Country Asia ex Japan ETF | 200,000 | $49,600,000 | |
| RVMD | Revolution Medicines, Inc. | 258,142 | $25,104,309 | |
| NVO | Novo Nordisk A S | 400,000 | $14,700,000 | |
| KPTI | Karyopharm Therapeutics Inc. | 2,573,435 | $14,334,032 | |
| ORKA | Oruka Therapeutics, Inc. | 242,021 | $11,871,130 | |
| PVLA | Palvella Therapeutics, Inc. | 64,626 | $8,055,630 | |
| LLY | ELI LILLY & Co | 6,547 | $6,021,734 | |
| SRZN | Surrozen, Inc./DE | 173,107 | $5,042,606 | |
| LEGN | Legend Biotech Corp | 226,888 | $4,104,403 | |
| FRNM | Freenome, Inc. | 240,951 | $2,643,232 | |
| VIR | Vir Biotechnology, Inc. | 293,258 | $2,627,591 | |
| BBOT | BridgeBio Oncology Therapeutics, Inc. | 270,231 | $2,418,567 | |
| JAZZ | Jazz Pharmaceuticals plc | 12,460 | $2,355,563 | |
| REPL | Replimune Group, Inc. | 300,000 | $2,295,000 | |
| AAPD | Direxion Shares ETF Trust Direxion Daily AAPL Bear 1X ETF | 105,822 | $1,724,898 | |
| QURE | uniQure N.V. | 91,060 | $1,488,831 | |
| DFTX | Definium Therapeutics, Inc. | 58,803 | $1,111,376 | |
| INSM | INSMED Inc | 4,214 | $689,073 | |
| SGMOQ | Sangamo Therapeutics, Inc | 1,218,671 | $304,667 | |
| VERU | Veru Inc. | 133,517 | $295,072 | |
| IOBTQ | IO Biotech, Inc. | 1,386,565 | $81,391 | |
| SHPH | Shuttle Pharmaceuticals Holdings, Inc. | 68,993 | $46,846 | |
| No positions match the current search. | ||||
133 tracked positions ·
$871,884,353 total
· filing declares
156 positions · $928,174,362
· as of Jun 30, 2026
Showing 1–50
of 133 positions by value
· page 1 of 3
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| ABVX |
Abivax S.A.
PUT
CALL
+ SHARES
Healthcare
|
Added | 919,735 | $122,563,886 | 14.06% | |
| IONS |
Ionis Pharmaceuticals Inc
PUT
CALL
Healthcare
|
Added | 700,000 | $55,503,000 | 6.37% | |
| KOD |
Kodiak Sciences Inc.
CALL
+ SHARES
Healthcare
|
Reduced | 1,277,430 | $49,768,672 | 5.71% | |
| ALMS |
Alumis Inc.
CALL
+ SHARES
Healthcare
|
Reduced | 1,226,848 | $34,523,502 | 3.96% | |
| PRAX |
Praxis Precision Medicines, Inc.
PUT
CALL
+ SHARES
Healthcare
|
Added | 93,742 | $31,383,884 | 3.60% | |
| MRNA |
Moderna, Inc.
PUT
Healthcare
|
NEW | 400,000 | $28,012,000 | 3.21% | |
| CAPR |
Capricor Therapeutics, Inc.
CALL
+ SHARES
Healthcare
|
Added | 954,215 | $22,977,497 | 2.64% | |
| PCVX |
Vaxcyte, Inc.
Healthcare
|
Reduced | 388,682 | $22,594,084 | 2.59% | |
| ANIP |
Ani Pharmaceuticals Inc
Healthcare
|
Reduced | 272,085 | $22,523,196 | 2.58% | |
| CLDX |
Celldex Therapeutics, Inc.
PUT
+ SHARES
Healthcare
|
Added | 592,500 | $22,046,925 | 2.53% | |
| TENX |
Tenax Therapeutics, Inc.
PUT
CALL
+ SHARES
Healthcare
|
Added | 1,177,200 | $17,128,260 | 1.96% | |
| VERA |
Vera Therapeutics, Inc.
CALL
+ SHARES
Healthcare
|
Added | 381,700 | $16,378,747 | 1.88% | |
| RCUS |
Arcus Biosciences, Inc.
Healthcare
|
NEW | 504,559 | $15,555,553 | 1.78% | |
| RLMD |
Relmada Therapeutics, Inc.
Healthcare
|
Reduced | 2,148,359 | $14,866,644 | 1.71% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
NEW | 370,084 | $14,322,250 | 1.64% | |
| CTNM |
Contineum Therapeutics, Inc.
Healthcare
|
Held | 807,874 | $13,241,054 | 1.52% | |
| CCCC |
C4 Therapeutics, Inc.
Healthcare
|
NEW | 2,433,000 | $11,362,110 | 1.30% | |
| MAZE |
Maze Therapeutics, Inc.
Healthcare
|
Reduced | 378,999 | $11,309,330 | 1.30% | |
| ARWR |
Arrowhead Pharmaceuticals, Inc.
PUT
+ SHARES
Healthcare
|
Added | 138,278 | $11,271,039 | 1.29% | |
| BHVN |
Biohaven Ltd.
Healthcare
|
Added | 748,181 | $11,132,933 | 1.28% | |
| CNTB |
Connect Biopharma Holdings Ltd
Healthcare
|
Reduced | 4,538,534 | $10,801,710 | 1.24% | |
| ANRO |
Alto Neuroscience, Inc.
Healthcare
|
Reduced | 407,338 | $10,749,649 | 1.23% | |
| PHVS |
Pharvaris N.V.
Healthcare
|
Reduced | 308,856 | $10,680,240 | 1.22% | |
| EYPT |
EyePoint, Inc.
PUT
CALL
Healthcare
|
Held | 740,800 | $10,593,440 | 1.22% | |
| JBIO |
Jade Biosciences, Inc.
Healthcare
|
Reduced | 427,349 | $9,495,694 | 1.09% | |
| SLN |
Silence Therapeutics plc
Healthcare
|
Reduced | 830,784 | $9,122,008 | 1.05% | |
| DMRA |
Damora Therapeutics, Inc.
Healthcare
|
Held | 335,710 | $8,731,817 | 1.00% | |
| QTTB |
Q32 Bio Inc.
PUT
+ SHARES
Healthcare
|
NEW | 630,000 | $8,026,200 | 0.92% | |
| VRDN |
Viridian Therapeutics, Inc.\DE
Healthcare
|
NEW | 425,000 | $7,807,250 | 0.90% | |
| OLMA |
Olema Pharmaceuticals, Inc.
CALL
+ SHARES
Healthcare
|
Reduced | 583,281 | $7,296,845 | 0.84% | |
| PTHS |
Pelthos Therapeutics Inc.
Healthcare
|
Held | 256,598 | $7,251,459 | 0.83% | |
| ZURA |
Zura Bio Ltd
Healthcare
|
Added | 1,218,492 | $7,189,102 | 0.82% | |
| TECX |
Tectonic Therapeutic, Inc.
Healthcare
|
Added | 205,837 | $7,076,676 | 0.81% | |
| SPRB |
Spruce Biosciences, Inc.
Healthcare
|
Held | 121,356 | $6,553,224 | 0.75% | |
| HIMS |
Hims & Hers Health, Inc.
Healthcare
|
NEW | 188,381 | $6,531,169 | 0.75% | |
| ELVN |
Enliven Therapeutics, Inc.
Healthcare
|
Added | 126,541 | $6,421,955 | 0.74% | |
| PRQR |
ProQR Therapeutics N.V.
Healthcare
|
Added | 3,425,930 | $6,372,229 | 0.73% | |
| DRUG |
Bright Minds Biosciences Inc.
Healthcare
|
Reduced | 88,951 | $6,244,360 | 0.72% | |
| OVID |
Ovid Therapeutics Inc.
Healthcare
|
Reduced | 2,269,704 | $6,105,503 | 0.70% | |
| OCGN |
Ocugen, Inc.
Healthcare
|
Held | 3,962,972 | $6,063,347 | 0.70% | |
| ACOG |
Alpha Cognition Inc.
Healthcare
|
Reduced | 836,259 | $6,037,789 | 0.69% | |
| KYMR |
Kymera Therapeutics, Inc.
PUT
Healthcare
|
Held | 50,400 | $5,779,368 | 0.66% | |
| HROW |
Harrow, Inc.
Healthcare
|
Reduced | 135,775 | $5,766,364 | 0.66% | |
| KZIA |
Kazia Therapeutics Ltd
Healthcare
|
NEW | 396,201 | $5,578,510 | 0.64% | |
| RARE |
Ultragenyx Pharmaceutical Inc.
Healthcare
|
Reduced | 165,617 | $5,529,951 | 0.63% | |
| EPRX |
Eupraxia Pharmaceuticals Inc.
Healthcare
|
Reduced | 809,741 | $5,352,388 | 0.61% | |
| SLS |
SELLAS Life Sciences Group, Inc.
PUT
Healthcare
|
NEW | 354,700 | $5,235,372 | 0.60% | |
| BIOA |
BioAge Labs, Inc.
Healthcare
|
NEW | 200,000 | $4,902,000 | 0.56% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
Added | 935,012 | $4,862,062 | 0.56% | |
| SION |
Sionna Therapeutics, Inc.
PUT
Healthcare
|
NEW | 107,500 | $4,728,925 | 0.54% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.