Catalio Capital Management, LP

CIK

1958125

Location

NEW YORK, NY

Portfolio Value

Small $478,705,573

Diversification

Diversified

Filing Date

Global Rank

#2,379 / 8,232 ▼ 34

Top Industry

Biotechnology 75.4%

3Y Alpha vs SPY

+7.7%

Period ended 2 months ago

Filed May 15, 2026 · 30d

6 quarters · since Dec 2024

Clone Performance

Feb 2025–Jun 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+34.2%

SPY

+23.4%

Annualised alpha

+7.6%

Max drawdown

−22.4%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

41 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

9.8%

+3.2 pts

Top 5

33.1%

+3.5 pts

Top 10

54.5%

+3.3 pts

HHI

428

Diversified+52

Portfolio Trend

6 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$478,705,573	41

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

12 positions

Ticker	Company	Δ Shares	Shares	Value
KPTI	Karyopharm Therapeutics Inc.	+754,725	897,709	$5,000,239
RARE	Ultragenyx Pharmaceutical Inc.	+688,247	850,797	$17,824,197
ELDN	Eledon Pharmaceuticals, Inc.	+379,996	1,639,816	$5,050,633
HTFL	Heartflow, Inc.	+289,731	403,588	$9,819,296
TERN	Terns Pharmaceuticals, Inc.	+272,073	409,031	$21,564,114
SLNO	Soleno Therapeutics Inc	+217,468	577,808	$19,345,011
QURE	uniQure N.V.	+202,771	491,116	$8,029,746
MLYS	Mineralys Therapeutics, Inc.	+107,192	439,041	$11,893,620
IRON	Disc Medicine, Inc.	+12,551	122,978	$7,863,213
ASND	Ascendis Pharma A/S	+9,846	129,111	$29,531,559
NTRA	Natera, Inc.	+8,634	70,907	$14,180,690
GPCR	Structure Therapeutics Inc.	+2,478	255,379	$12,309,267
No positions match the current search.

Trimmed

Positions the filer reduced

13 positions

Ticker	Company	Δ Shares	Shares	Value
TARA	Protara Therapeutics, Inc.	−866,230	580,024	$3,021,925
PHAT	Phathom Pharmaceuticals, Inc.	−451,229	247,767	$2,752,691
DYN	Dyne Therapeutics, Inc.	−236,761	282,954	$5,129,956
BMY	Bristol Myers Squibb Co	−227,172	420,727	$25,517,092
SUPN	Supernus Pharmaceuticals, Inc.	−195,446	62,019	$3,205,762
SNDX	Syndax Pharmaceuticals Inc	−153,137	1,043,670	$24,380,131
GILD	Gilead Sciences, Inc.	−125,407	163,905	$22,843,439
ADPT	Adaptive Biotechnologies Corp	−98,411	722,784	$10,032,241
DNTH	Dianthus Therapeutics, Inc. /DE/	−93,264	560,308	$47,021,047
BSX	Boston Scientific Corp	−61,110	299,318	$18,782,204
ABVX	Abivax S.A.	−51,321	47,193	$5,254,940
CYTK	Cytokinetics Inc	−42,880	215,501	$14,203,670
EW	Edwards Lifesciences Corp	−42,441	144,607	$11,580,128
No positions match the current search.

New Positions

Positions the filer opened this quarter

10 positions

Ticker	Company	Shares	Value
BBIO	BridgeBio Pharma, Inc.	432,014	$32,081,359
DFTX	Definium Therapeutics, Inc.	1,037,984	$19,617,897
INCY	Incyte Corp	182,101	$17,139,346
CRVS	Corvus Pharmaceuticals, Inc.	891,933	$13,048,979
MANE	Veradermics, Inc	173,582	$10,961,703
KALV	KalVista Pharmaceuticals, Inc.	426,551	$8,586,471
NAMS	NewAmsterdam Pharma Co N.V.	83,554	$2,674,563
TYRA	Tyra Biosciences, Inc.	67,285	$2,577,015
IMCR	Immunocore Holdings plc	84,352	$2,543,212
ATAI	AtaiBeckley Inc.	196,858	$696,877
No positions match the current search.

Sold Out

Positions the filer fully exited

13 positions

Ticker	Company	Shares	Value
LLY	ELI LILLY & Co	25,923	$27,858,932
JNJ	Johnson & Johnson	120,840	$25,007,838
REGN	Regeneron Pharmaceuticals, Inc.	29,797	$22,999,410
ISRG	Intuitive Surgical Inc	27,209	$15,410,089
ADMA	Adma Biologics, Inc.	564,461	$10,295,768
ACLX	Arcellx, Inc.	156,109	$10,178,306
OCUL	Ocular Therapeutix, Inc	714,501	$8,674,042
OLMA	Olema Pharmaceuticals, Inc.	267,058	$6,676,450
BBOT	BridgeBio Oncology Therapeutics, Inc.	410,700	$5,141,964
GRAL	GRAIL, Inc.	30,313	$2,594,489
FULC	Fulcrum Therapeutics, Inc.	201,301	$2,276,714
BLLN	BillionToOne, Inc.	25,505	$2,087,329
PVLA	Palvella Therapeutics, Inc.	10,452	$1,094,010
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

41 positions · $478,705,573 total · as of Mar 31, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	Reduced	560,308	-93,264	$47,021,047	+74.6%	9.82%
BBIO	BridgeBio Pharma, Inc. Healthcare	NEW	432,014	NEW	$32,081,359	NEW	6.70%
ASND	Ascendis Pharma A/S Healthcare	Added	129,111	+9,846	$29,531,559	+16.1%	6.17%
BMY	Bristol Myers Squibb Co Healthcare	Reduced	420,727	-227,172	$25,517,092	−27.0%	5.33%
SNDX	Syndax Pharmaceuticals Inc Healthcare	Reduced	1,043,670	-153,137	$24,380,131	−3.0%	5.09%
GILD	Gilead Sciences, Inc. Healthcare	Reduced	163,905	-125,407	$22,843,439	−35.7%	4.77%
TERN	Terns Pharmaceuticals, Inc. Healthcare	Added	409,031	+272,073	$21,564,114	+289.7%	4.50%
DFTX	Definium Therapeutics, Inc. Healthcare	NEW	1,037,984	NEW	$19,617,897	NEW	4.10%
SLNO	Soleno Therapeutics Inc Healthcare	Added	577,808	+217,468	$19,345,011	+16.0%	4.04%
BSX	Boston Scientific Corp Healthcare	Reduced	299,318	-61,110	$18,782,204	−45.3%	3.92%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	Added	850,797	+688,247	$17,824,197	+376.8%	3.72%
INCY	Incyte Corp Healthcare	NEW	182,101	NEW	$17,139,346	NEW	3.58%
CYTK	Cytokinetics Inc Healthcare	Reduced	215,501	-42,880	$14,203,670	−13.5%	2.97%
NTRA	Natera, Inc. Healthcare	Added	70,907	+8,634	$14,180,690	−0.6%	2.96%
CRVS	Corvus Pharmaceuticals, Inc. Healthcare	NEW	891,933	NEW	$13,048,979	NEW	2.73%
GPCR	Structure Therapeutics Inc. Healthcare	Added	255,379	+2,478	$12,309,267	−30.0%	2.57%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Added	439,041	+107,192	$11,893,620	−1.2%	2.48%
EW	Edwards Lifesciences Corp Healthcare	Reduced	144,607	-42,441	$11,580,128	−27.4%	2.42%
MANE	Veradermics, Inc Healthcare	NEW	173,582	NEW	$10,961,703	NEW	2.29%
ADPT	Adaptive Biotechnologies Corp Healthcare	Reduced	722,784	-98,411	$10,032,241	−24.8%	2.10%
HTFL	Heartflow, Inc. Healthcare	Added	403,588	+289,731	$9,819,296	+195.9%	2.05%
KALV	KalVista Pharmaceuticals, Inc. Healthcare	NEW	426,551	NEW	$8,586,471	NEW	1.79%
QURE	uniQure N.V. Healthcare	Added	491,116	+202,771	$8,029,746	+16.4%	1.68%
IRON	Disc Medicine, Inc. Healthcare	Added	122,978	+12,551	$7,863,213	−10.3%	1.64%
SEPN	Septerna, Inc. Healthcare	Held	294,360	0	$7,073,470	−13.8%	1.48%
ABVX	Abivax S.A. Healthcare	Reduced	47,193	-51,321	$5,254,940	−60.4%	1.10%
DYN	Dyne Therapeutics, Inc. Healthcare	Reduced	282,954	-236,761	$5,129,956	−49.5%	1.07%
ELDN	Eledon Pharmaceuticals, Inc. Healthcare	Added	1,639,816	+379,996	$5,050,633	+165.5%	1.06%
KPTI	Karyopharm Therapeutics Inc. Healthcare	Added	897,709	+754,725	$5,000,239	+375.1%	1.04%
SUPN	Supernus Pharmaceuticals, Inc. Healthcare	Reduced	62,019	-195,446	$3,205,762	−74.9%	0.67%
TARA	Protara Therapeutics, Inc. Healthcare	Reduced	580,024	-866,230	$3,021,925	−60.8%	0.63%
PHAT	Phathom Pharmaceuticals, Inc. Healthcare	Reduced	247,767	-451,229	$2,752,691	−76.3%	0.58%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	NEW	83,554	NEW	$2,674,563	NEW	0.56%
TYRA	Tyra Biosciences, Inc. Healthcare	NEW	67,285	NEW	$2,577,015	NEW	0.54%
IMCR	Immunocore Holdings plc Healthcare	NEW	84,352	NEW	$2,543,212	NEW	0.53%
GUTS	Fractyl Health, Inc. Healthcare	Held	5,491,866	0	$2,515,274	−79.2%	0.53%
HYPR	Hyperfine, Inc. Healthcare	Held	1,320,041	0	$1,425,644	+10.3%	0.30%
MGX	Metagenomi Therapeutics, Inc. Healthcare	Held	528,993	0	$708,850	−17.3%	0.15%
ATAI	AtaiBeckley Inc. Healthcare	NEW	196,858	NEW	$696,877	NEW	0.15%
SNSE	Sensei Biotherapeutics, Inc. Healthcare	Held	14,718	0	$463,911	+195.4%	0.10%
OM	Outset Medical, Inc. Healthcare	Held	118,279	0	$454,191	+3.5%	0.09%