Catalio Capital Management, LP
Filing Date
Global Rank
#2,710
/ 8,622
▼ 125
· as of Mar 2026
Top Industry
Biotechnology
76.6%
3Y Alpha vs SPY
+19.9%
Period ended 4 months ago
Filed May 15, 2026 · 3mo
6 quarters · since Dec 2024
Clone Performance
Feb 2025–Jul 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+52.2%
SPY
+23.3%
Annualised alpha
+18.0%
Max drawdown
−22.2%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 6 quarters. Past performance does not predict future results.
Portfolio Concentration
41 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
10.0%
+3.3 pts
Top 5
33.6%
+3.5 pts
Top 10
55.3%
+3.2 pts
HHI
437
Diversified+54
Portfolio Trend
6 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $471,181,392 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
12 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| KPTI | Karyopharm Therapeutics Inc. | +754,725 | 897,709 | $5,000,239 | |
| RARE | Ultragenyx Pharmaceutical Inc. | +688,247 | 850,797 | $17,824,197 | |
| ELDN | Eledon Pharmaceuticals, Inc. | +379,996 | 1,639,816 | $5,050,633 | |
| HTFL | Heartflow, Inc. | +289,731 | 403,588 | $9,819,296 | |
| TERN | Terns Pharmaceuticals, Inc. | +272,073 | 409,031 | $21,564,114 | |
| SLNO | Soleno Therapeutics Inc | +217,468 | 577,808 | $19,345,011 | |
| QURE | uniQure N.V. | +202,771 | 491,116 | $8,029,746 | |
| MLYS | Mineralys Therapeutics, Inc. | +107,192 | 439,041 | $11,893,620 | |
| IRON | Disc Medicine, Inc. | +12,551 | 122,978 | $7,863,213 | |
| ASND | Ascendis Pharma A/S | +9,846 | 129,111 | $29,531,559 | |
| NTRA | Natera, Inc. | +8,634 | 70,907 | $14,180,690 | |
| GPCR | Structure Therapeutics Inc. | +2,478 | 255,379 | $12,309,267 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
13 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| TARA | Protara Therapeutics, Inc. | −866,230 | 580,024 | $3,021,925 | |
| PHAT | Phathom Pharmaceuticals, Inc. | −451,229 | 247,767 | $2,752,691 | |
| DYN | Dyne Therapeutics, Inc. | −236,761 | 282,954 | $5,129,956 | |
| BMY | Bristol Myers Squibb Co | −227,172 | 420,727 | $25,517,092 | |
| SUPN | Supernus Pharmaceuticals, Inc. | −195,446 | 62,019 | $3,205,762 | |
| SNDX | Syndax Pharmaceuticals Inc | −153,137 | 1,043,670 | $24,380,131 | |
| GILD | Gilead Sciences, Inc. | −125,407 | 163,905 | $22,843,439 | |
| ADPT | Adaptive Biotechnologies Corp | −98,411 | 722,784 | $2,508,060 | |
| DNTH | Dianthus Therapeutics, Inc. /DE/ | −93,264 | 560,308 | $47,021,047 | |
| BSX | Boston Scientific Corp | −61,110 | 299,318 | $18,782,204 | |
| ABVX | Abivax S.A. | −51,321 | 47,193 | $5,254,940 | |
| CYTK | Cytokinetics Inc | −42,880 | 215,501 | $14,203,670 | |
| EW | Edwards Lifesciences Corp | −42,441 | 144,607 | $11,580,128 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
10 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| BBIO | BridgeBio Pharma, Inc. | 432,014 | $32,081,359 | |
| DFTX | Definium Therapeutics, Inc. | 1,037,984 | $19,617,897 | |
| INCY | Incyte Corp | 182,101 | $17,139,346 | |
| CRVS | Corvus Pharmaceuticals, Inc. | 891,933 | $13,048,979 | |
| MANE | Veradermics, Inc | 173,582 | $10,961,703 | |
| KALV | KalVista Pharmaceuticals, Inc. | 426,551 | $8,586,471 | |
| NAMS | NewAmsterdam Pharma Co N.V. | 83,554 | $2,674,563 | |
| TYRA | Tyra Biosciences, Inc. | 67,285 | $2,577,015 | |
| IMCR | Immunocore Holdings plc | 84,352 | $2,543,212 | |
| ATAI | AtaiBeckley Inc. | 196,858 | $696,877 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
13 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| LLY | ELI LILLY & Co | 25,923 | $27,858,932 | |
| JNJ | Johnson & Johnson | 120,840 | $25,007,838 | |
| REGN | Regeneron Pharmaceuticals, Inc. | 29,797 | $22,999,410 | |
| ISRG | Intuitive Surgical Inc | 27,209 | $15,410,089 | |
| ADMA | Adma Biologics, Inc. | 564,461 | $10,295,768 | |
| ACLX | Arcellx, Inc. | 156,109 | $10,178,306 | |
| OCUL | Ocular Therapeutix, Inc | 714,501 | $8,674,042 | |
| OLMA | Olema Pharmaceuticals, Inc. | 267,058 | $6,676,450 | |
| BBOT | BridgeBio Oncology Therapeutics, Inc. | 410,700 | $5,141,964 | |
| GRAL | GRAIL, Inc. | 30,313 | $2,594,489 | |
| FULC | Fulcrum Therapeutics, Inc. | 201,301 | $2,276,714 | |
| BLLN | BillionToOne, Inc. | 25,505 | $2,087,329 | |
| PVLA | Palvella Therapeutics, Inc. | 10,452 | $1,094,010 | |
| No positions match the current search. | ||||
41 tracked positions ·
$471,181,392 total
· filing declares
41 positions · $478,704,496
· as of Mar 31, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| DNTH |
Dianthus Therapeutics, Inc. /DE/
Healthcare
|
Reduced | 560,308 | $47,021,047 | 9.98% | |
| BBIO |
BridgeBio Pharma, Inc.
Healthcare
|
NEW | 432,014 | $32,081,359 | 6.81% | |
| ASND |
Ascendis Pharma A/S
Healthcare
|
Added | 129,111 | $29,531,559 | 6.27% | |
| BMY |
Bristol Myers Squibb Co
Healthcare
|
Reduced | 420,727 | $25,517,092 | 5.42% | |
| SNDX |
Syndax Pharmaceuticals Inc
Healthcare
|
Reduced | 1,043,670 | $24,380,131 | 5.17% | |
| GILD |
Gilead Sciences, Inc.
Healthcare
|
Reduced | 163,905 | $22,843,439 | 4.85% | |
| TERN |
Terns Pharmaceuticals, Inc.
Healthcare
|
Added | 409,031 | $21,564,114 | 4.58% | |
| DFTX |
Definium Therapeutics, Inc.
Healthcare
|
NEW | 1,037,984 | $19,617,897 | 4.16% | |
| SLNO |
Soleno Therapeutics Inc
Healthcare
|
Added | 577,808 | $19,345,011 | 4.11% | |
| BSX |
Boston Scientific Corp
Healthcare
|
Reduced | 299,318 | $18,782,204 | 3.99% | |
| RARE |
Ultragenyx Pharmaceutical Inc.
Healthcare
|
Added | 850,797 | $17,824,197 | 3.78% | |
| INCY |
Incyte Corp
Healthcare
|
NEW | 182,101 | $17,139,346 | 3.64% | |
| CYTK |
Cytokinetics Inc
Healthcare
|
Reduced | 215,501 | $14,203,670 | 3.01% | |
| NTRA |
Natera, Inc.
Healthcare
|
Added | 70,907 | $14,180,690 | 3.01% | |
| CRVS |
Corvus Pharmaceuticals, Inc.
Healthcare
|
NEW | 891,933 | $13,048,979 | 2.77% | |
| GPCR |
Structure Therapeutics Inc.
Healthcare
|
Added | 255,379 | $12,309,267 | 2.61% | |
| MLYS |
Mineralys Therapeutics, Inc.
Healthcare
|
Added | 439,041 | $11,893,620 | 2.52% | |
| EW |
Edwards Lifesciences Corp
Healthcare
|
Reduced | 144,607 | $11,580,128 | 2.46% | |
| MANE |
Veradermics, Inc
Healthcare
|
NEW | 173,582 | $10,961,703 | 2.33% | |
| HTFL |
Heartflow, Inc.
Healthcare
|
Added | 403,588 | $9,819,296 | 2.08% | |
| KALV |
KalVista Pharmaceuticals, Inc.
Healthcare
|
NEW | 426,551 | $8,586,471 | 1.82% | |
| QURE |
uniQure N.V.
Healthcare
|
Added | 491,116 | $8,029,746 | 1.70% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
Added | 122,978 | $7,863,213 | 1.67% | |
| SEPN |
Septerna, Inc.
Healthcare
|
Held | 294,360 | $7,073,470 | 1.50% | |
| ABVX |
Abivax S.A.
Healthcare
|
Reduced | 47,193 | $5,254,940 | 1.12% | |
| DYN |
Dyne Therapeutics, Inc.
Healthcare
|
Reduced | 282,954 | $5,129,956 | 1.09% | |
| ELDN |
Eledon Pharmaceuticals, Inc.
Healthcare
|
Added | 1,639,816 | $5,050,633 | 1.07% | |
| KPTI |
Karyopharm Therapeutics Inc.
Healthcare
|
Added | 897,709 | $5,000,239 | 1.06% | |
| SUPN |
Supernus Pharmaceuticals, Inc.
Healthcare
|
Reduced | 62,019 | $3,205,762 | 0.68% | |
| TARA |
Protara Therapeutics, Inc.
Healthcare
|
Reduced | 580,024 | $3,021,925 | 0.64% | |
| PHAT |
Phathom Pharmaceuticals, Inc.
Healthcare
|
Reduced | 247,767 | $2,752,691 | 0.58% | |
| NAMS |
NewAmsterdam Pharma Co N.V.
Healthcare
|
NEW | 83,554 | $2,674,563 | 0.57% | |
| TYRA |
Tyra Biosciences, Inc.
Healthcare
|
NEW | 67,285 | $2,577,015 | 0.55% | |
| IMCR |
Immunocore Holdings plc
Healthcare
|
NEW | 84,352 | $2,543,212 | 0.54% | |
| GUTS |
Fractyl Health, Inc.
Healthcare
|
Held | 5,491,866 | $2,515,274 | 0.53% | |
| ADPT |
Adaptive Biotechnologies Corp
Healthcare
|
Reduced | 722,784 | $2,508,060 | 0.53% | |
| HYPR |
Hyperfine, Inc.
Healthcare
|
Held | 1,320,041 | $1,425,644 | 0.30% | |
| MGX |
Metagenomi Therapeutics, Inc.
Healthcare
|
Held | 528,993 | $708,850 | 0.15% | |
| ATAI |
AtaiBeckley Inc.
Healthcare
|
NEW | 196,858 | $696,877 | 0.15% | |
| FTH |
Faeth Therapeutics, Inc.
Healthcare
|
Held | 14,718 | $463,911 | 0.10% | |
| OM |
Outset Medical, Inc.
Healthcare
|
Held | 118,279 | $454,191 | 0.10% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.