GENB · Generate Biomedicines, Inc.

$16.27 +0.28 (+1.75%)

Market Cap

$2.18B

128.35M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 85

Total Value: $1,687,766,066

Total Shares: 100,045,413

Institutional Ownership Trend

2 quarters

Holder Concentration

Across 85 13F filers · Δ vs Mar 31, 2026

Top Holder

62.6%

−4.9 pts

Top 5

77.5%

−5.9 pts

Top 10

86.4%

−6.0 pts

HHI

4,012

Highly concentrated−630

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +27

Institutional value: +45.4%

Shares held: +7.8%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega FMR LLC	+1,004,075	5,221,599
Mega VANGUARD CAPITAL MANAGEMENT LLC	+1,001,431	1,132,750
Large ARK Investment Management LLC	+786,209	1,284,617
Mega GEODE CAPITAL MANAGEMENT, LLC	+616,760	735,003
Small Davern Capital Partners, LP	+232,879	824,679

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega JPMORGAN CHASE & CO	−1,537,610	1,409,649
Mega MILLENNIUM MANAGEMENT LLC	−354,967	21,926
Mid BRAIDWELL LP	−309,155	3,283,844
Mega GOLDMAN SACHS GROUP INC	−159,512	11,183
Mid CenterBook Partners LP	−135,253	131,560

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega NORGES BANK	2,094,616	$35,336,171
Mega BlackRock, Inc.	1,659,966	$28,003,623
Mid Deep Track Capital, LP	1,333,815	$22,501,459
Mega STATE STREET CORP	526,565	$8,883,151
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC	224,602	$3,789,035

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large Alyeska Investment Group, L.P.	500,000	$6,250,000
Large ExodusPoint Capital Management, LP	311,986	$3,899,825
Mega JANE STREET GROUP, LLC	123,371	$1,542,137
Small SILVERARC CAPITAL MANAGEMENT, LLC	100,000	$1,250,000
Mega D. E. Shaw & Co., Inc.	95,000	$1,187,500

Filter: New 41 Increased 24 Reduced 10 Sold out 14 Unchanged 10

Showing 85 of 85

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Flagship Pioneering, LLC

$1,057,295,483

62.64%

62,673,117

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Noubar Afeyan	62,673,117	$1,057,295,483	100.0%	Defined

FMR LLC

$88,088,374

5.22%

5,221,599

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	2,786,975	$47,016,268	53.4%	Defined
FIDELITY MANAGEMENT TRUST CO	2,434,624	$41,072,106	46.6%	Defined

Capital World Investors

$71,117,711

4.21%

4,215,632

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	4,215,632	$71,117,711	100.0%	Defined

BRAIDWELL LP

$55,398,448

3.28%

3,283,844

PRICE T ROWE ASSOCIATES INC /MD/

$36,382,297

2.16%

2,156,627

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	20,312	$342,663	0.9%	Defined
Held directly	2,136,315	$36,039,634	99.1%	Sole

NORGES BANK

$35,336,171

2.09%

2,094,616

ARCH Venture Management, LLC

$32,802,466

1.94%

1,944,426

HarbourVest Partners LLC

$29,053,682

1.72%

1,722,210

BlackRock, Inc.

$28,003,623

1.66%

1,659,966

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	6,073	$102,451	0.4%	Sole
BlackRock Investment Management, LLC	66,272	$1,118,008	4.0%	Sole
BLACKROCK ADVISORS LLC	53,274	$898,732	3.2%	Sole
BlackRock Fund Advisors	845,588	$14,265,069	50.9%	Sole
BlackRock Institutional Trust Company, N.A.	688,604	$11,616,749	41.5%	Sole
Aperio Group, LLC	155	$2,614	0.0%	Sole

BAKER BROS. ADVISORS LP

$24,016,165

1.42%

1,423,602

JPMORGAN CHASE & CO

$23,780,777

1.41%

1,409,649

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	43,224	$729,188	3.1%	Defined
J.P. Morgan Investment Management Inc.	1,061,581	$17,908,871	75.3%	Defined
J.P. Morgan Securities LLC	500	$8,435	0.0%	Defined
JPMorgan Asset Management (UK) Ltd	304,344	$5,134,283	21.6%	Defined

Deep Track Capital, LP

$22,501,459

1.33%

1,333,815

ARK Investment Management LLC

$21,671,488

1.28%

1,284,617

VANGUARD CAPITAL MANAGEMENT LLC

$19,109,492

1.13%

1,132,750

HARVARD MANAGEMENT CO INC

$18,744,257

1.11%

1,111,100

NVIDIA CORP

$14,058,192

0.83%

833,325

Davern Capital Partners, LP

$13,912,334

0.82%

824,679

Siren, L.L.C.

$12,418,074

0.74%

736,104

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	736,104	$12,418,074	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$12,399,500

0.73%

735,003

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	95,505	$1,611,169	13.0%	Defined
Held directly	639,498	$10,788,331	87.0%	Defined

STATE STREET CORP

$8,883,151

0.53%

526,565

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	526,565	$8,883,151	100.0%	Defined

Affinity Asset Advisors, LLC

$6,748,000

0.40%

400,000

MORGAN STANLEY

$6,376,756

0.38%

377,994

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	15	$253	0.0%	Defined
MORGAN STANLEY & CO. LLC	16,924	$285,507	4.5%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	1,834	$30,939	0.5%	Defined
MORGAN STANLEY SMITH BARNEY LLC	40,802	$688,329	10.8%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	5,919	$99,853	1.6%	Defined
Eaton Vance Advisers International Ltd	312,500	$5,271,875	82.7%	Defined

UBS Group AG

$5,504,225

0.33%

326,273

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	317,846	$5,362,062	97.4%	Defined
UBS Switzerland AG	8,427	$142,163	2.6%	Defined

SPHERA FUNDS MANAGEMENT LTD.

$4,133,150

0.24%

245,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	245,000	$4,133,150	100.0%	Defined

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$3,789,035

0.22%

224,602

NORTHERN TRUST CORP

$3,332,549

0.20%

197,543

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	193,694	$3,267,617	98.1%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	3,849	$64,932	1.9%	Other

VANGUARD FIDUCIARY TRUST CO

$2,958,255

0.18%

175,356

VANGUARD PORTFOLIO MANAGEMENT LLC

$2,822,097

0.17%

167,285

CenterBook Partners LP

$2,219,417

0.13%

131,560

ALPS ADVISORS INC

$2,183,079

0.13%

129,406

SEVEN GRAND MANAGERS, LLC

$2,108,750

0.12%

125,000

BARCLAYS PLC

$1,972,136

0.12%

116,902

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	112,313	$1,894,720	96.1%	Defined
BARCLAYS CAPITAL INC.	4,589	$77,416	3.9%	Defined

LMR Partners LLP

$1,687,000

0.10%

100,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
LMR Partners LLC	100,000	$1,687,000	100.0%	Sole

AMERIPRISE FINANCIAL INC

$1,536,856

0.09%

91,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	91,040	$1,535,844	99.9%	Defined
Ameriprise Financial Services, LLC	60	$1,012	0.1%	Defined

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$1,430,626

0.08%

84,803

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	84,803	$1,430,626	100.0%	Defined

Bank of New York Mellon Corp

$967,088

0.06%

57,326

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	16,362	$276,026	28.5%	Defined
The Bank of New York Mellon	40,964	$691,062	71.5%	Defined

BANK OF AMERICA CORP /DE/

$935,103

0.06%

55,430

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	14,116	$238,136	25.5%	Defined
BOFA SECURITIES, INC.	41,314	$696,967	74.5%	Defined

TD Asset Management Inc

$856,118

0.05%

50,748

Nuveen, LLC

$750,208

0.04%

44,470

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	12,088	$203,924	27.2%	Defined
TEACHERS ADVISORS, LLC joint	32,382	$546,284	72.8%	Defined

RENAISSANCE TECHNOLOGIES LLC

$669,485

0.04%

39,685

Sumitomo Mitsui Trust Group, Inc.

$652,278

0.04%

38,665

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amova Asset Management Co., Ltd.	38,665	$652,278	100.0%	Defined

Amova Asset Management Americas, Inc.

$644,737

0.04%

38,218

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sumitomo Mitsui Trust Group, Inc. joint	38,218	$644,737	100.0%	Sole

IQ EQ FUND MANAGEMENT (IRELAND) Ltd

$628,002

0.04%

37,226

Quadrature Capital Ltd

$531,573

0.03%

31,510

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	31,510	$531,573	100.0%	Other

Squarepoint Ops LLC

$529,819

0.03%

31,406

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	31,406	$529,819	100.0%	Defined

RHUMBLINE ADVISERS

$517,031

0.03%

30,648

CITIGROUP INC

$516,001

0.03%

30,587

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	30,587	$516,001	100.0%	Defined

Virtus Investment Advisers, LLC

$445,874

0.03%

26,430

XTX Topco Ltd

$421,007

0.02%

24,956

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	24,956	$421,007	100.0%	Defined

DEUTSCHE BANK AG\

$407,156

0.02%

24,135

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	327	$5,516	1.4%	Defined
DWS Investments UK Ltd	23,808	$401,640	98.6%	Defined

WELLS FARGO & COMPANY/MN

$393,104

0.02%

23,302

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	21,702	$366,112	93.1%	Defined
WELLS FARGO CLEARING SERVICES, LLC	1,600	$26,992	6.9%	Defined

ALLIANCEBERNSTEIN L.P.

$382,105

0.02%

22,650

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	22,650	$382,105	100.0%	Defined

MILLENNIUM MANAGEMENT LLC

$369,891

0.02%

21,926

TWO SIGMA INVESTMENTS, LP

$309,969

0.02%

18,374

Magnus Financial Group LLC

$263,172

0.02%

15,600

MetLife Investment Management, LLC

$250,367

0.01%

14,841

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	14,841	$250,367	100.0%	Defined

Invesco Ltd.

$220,777

0.01%

13,087

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	3,353	$56,565	25.6%	Defined
Invesco Trust Co joint	9,734	$164,212	74.4%	Defined

AXQ CAPITAL, LP

$218,399

0.01%

12,946

SEI INVESTMENTS CO

$203,924

0.01%

12,088

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI TRUST CO	12,088	$203,924	100.0%	Sole

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$196,063

0.01%

11,622

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	11,622	$196,063	100.0%	Other

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$188,825

0.01%

11,193

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	11,193	$188,825	100.0%	Defined

Parallel Advisors, LLC

$188,792

0.01%

11,191

GOLDMAN SACHS GROUP INC

$188,657

0.01%

11,183

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	11,183	$188,657	100.0%	Defined

Vanguard Global Advisers, LLC

$187,054

0.01%

11,088

SG Americas Securities, LLC

$156,502

0.01%

9,277

NEW YORK STATE COMMON RETIREMENT FUND

$145,082

0.01%

8,600

Police & Firemen's Retirement System of New Jersey

$121,464

0.01%

7,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	7,200	$121,464	100.0%	Defined

FEDERATED HERMES, INC.

$84,350

0.00%

5,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	2,000	$33,740	40.0%	Defined
FEDERATED GLOBAL INVESTMENT MANAGEMENT CORP	3,000	$50,610	60.0%	Defined

ALBION FINANCIAL GROUP /UT

$81,886

0.00%

4,854

STRS OHIO

$80,976

0.00%

4,800

BNP PARIBAS ARBITRAGE, SA

$64,106

0.00%

3,800

Legal & General Group Plc

$40,049

0.00%

2,374

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	2,374	$40,049	100.0%	Defined

Ameritas Investment Partners, Inc.

$37,367

0.00%

2,215

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	2,215	$37,367	100.0%	Other

Russell Investments Group, Ltd.

$32,930

0.00%

1,952

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	1,952	$32,930	100.0%	Defined

State of Wyoming

$23,736

0.00%

1,407

STANCE CAPITAL LLC

$23,348

0.00%

1,384

ROYAL BANK OF CANADA

$23,297

0.00%

1,381

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	761	$12,838	55.1%	Defined
RBC Capital Markets, LLC	620	$10,459	44.9%	Defined

Tower Research Capital LLC (TRC)

$17,106

0.00%

1,014

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	1,014	$17,106	100.0%	Defined

TD Waterhouse Canada Inc.

$9,666

0.00%

573

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	573	$9,666	100.0%	Defined

Benson Wealth Management INC

$6,123

0.00%

363

Sterling Capital Management LLC

$3,576

0.00%

212

JONES FINANCIAL COMPANIES LLLP

$3,374

0.00%

200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	200	$3,374	100.0%	Sole

Avion Wealth

$3,374

0.00%

200

HOLLENCREST CAPITAL MANAGEMENT

$84

0.00%

Caitong International Asset Management Co., Ltd

$16

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	123,371	$1,542,137	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	95,000	$1,187,500	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Hudson Bay Capital UK LLP	16,678	$208,475	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brevan Howard US Investment Management, LP	12,571	$157,137	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Thakore Nainoor	10,497	$131,212	100.0%	Defined

Key facts CIK 2100782 CUSIP 370920100 13F (30d) 84 filings 84 filers Visit website