Redmile Group, LLC

CIK

1425738

Location

Larkspur, CA

Portfolio Value

Mid $1,510,149,025

Diversification

Diversified

Filing Date

Global Rank

#1,312 / 8,636 ▲ 127 · as of Mar 2026

Top Industry

Biotechnology 94.8%

3Y Alpha vs SPY

-6.3%

Period ended 4 months ago

Filed May 15, 2026 · 3mo

25 quarters · since Mar 2020

Clone Performance

Aug 2023–Aug 2026 · vs SPY

Hypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.

Cloned portfolio

+60.8%

SPY

+78.8%

Annualised alpha

-4.2%

Max drawdown

−54.1%

Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 13 quarters. Past performance does not predict future results.

Portfolio Concentration

35 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

29.5%

+12.1 pts

Top 5

66.0%

+5.5 pts

Top 10

81.9%

+2.1 pts

HHI

1,290

Diversified+410

Portfolio Trend

25 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$1,510,149,025	35

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

6 positions

Ticker	Company	Δ Shares	Shares	Value
ALXO	Alx Oncology Holdings Inc	+4,699,470	7,964,188	$15,968,196
ANNX	Annexon, Inc.	+4,499,124	14,549,768	$80,605,714
SRRK	Scholar Rock Holding Corp	+3,845,775	9,066,621	$445,715,088
SLDB	Solid Biosciences Inc.	+151,353	2,011,895	$14,485,644
STOK	Stoke Therapeutics, Inc.	+130,050	4,164,120	$135,583,747
XENE	Xenon Pharmaceuticals Inc.	+128,792	262,674	$15,274,493
No positions match the current search.

Trimmed

Positions the filer reduced

16 positions

Ticker	Company	Δ Shares	Shares	Value
PLRX	Pliant Therapeutics, Inc.	−844,102	772,126	$972,878
COGT	Cogent Biosciences, Inc.	−749,882	688,036	$26,482,505
NRIX	Nurix Therapeutics, Inc.	−361,100	7,732,808	$119,858,524
IDYA	IDEAYA Biosciences, Inc.	−220,900	521,117	$17,363,618
ADCT	ADC Therapeutics SA	−196,229	15,470,502	$58,014,382
IMNM	Immunome Inc.	−159,500	5,558,885	$121,572,814
DBVT	DBV Technologies S.A.	−58,500	491,340	$10,264,092
CBLL	Ceribell, Inc.	−48,453	386,786	$7,089,787
BEAM	Beam Therapeutics Inc.	−48,200	1,237,659	$29,493,413
IVVD	Invivyd, Inc.	−32,500	2,648,659	$3,443,256
ORIC	Oric Pharmaceuticals, Inc.	−32,400	415,710	$5,267,045
CLDX	Celldex Therapeutics, Inc.	−21,800	261,508	$8,295,033
NUVB	Nuvation Bio Inc.	−10,000	3,153,256	$13,527,468
LIVN	LivaNova PLC	−9,700	108,354	$6,886,980
ESTA	Establishment Labs Holdings Inc.	−9,200	103,464	$5,874,685
KRYS	Krystal Biotech, Inc.	−4,200	673,505	$173,979,811
No positions match the current search.

New Positions

Positions the filer opened this quarter

5 positions

Ticker	Company	Shares	Value
BMRN	Biomarin Pharmaceutical Inc	173,859	$9,821,294
PRME	Prime Medicine, Inc.	1,590,832	$5,536,095
EPRX	Eupraxia Pharmaceuticals Inc.	700,000	$5,068,000
ARDX	Ardelyx, Inc.	733,350	$4,392,766
AGMB	Agomab Therapeutics NV	156,250	$1,639,062
No positions match the current search.

Sold Out

Positions the filer fully exited

2 positions

Ticker	Company	Shares	Value
REPL	Replimune Group, Inc.	1,099,756	$10,689,628
KLRS	Kalaris Therapeutics, Inc.	82,955	$700,140
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

35 tracked positions · $1,510,149,025 total · as of Mar 31, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
SRRK	Scholar Rock Holding Corp Healthcare	Added	9,066,621	+3,845,775	$445,715,088	+93.8%	29.51%
KRYS	Krystal Biotech, Inc. Healthcare	Reduced	673,505	-4,200	$173,979,811	+4.1%	11.52%
STOK	Stoke Therapeutics, Inc. Healthcare	Added	4,164,120	+130,050	$135,583,747	+5.9%	8.98%
IMNM	Immunome Inc. Healthcare	Reduced	5,558,885	-5,877,885	$121,572,814	−50.5%	8.05%
NRIX	Nurix Therapeutics, Inc. Healthcare	Reduced	7,732,808	-361,100	$119,858,524	−21.9%	7.94%
ANNX	Annexon, Inc. Healthcare	Added	14,549,768	+4,499,124	$80,605,714	+59.8%	5.34%
ADCT	ADC Therapeutics SA Healthcare	Reduced	15,470,502	-196,229	$58,014,382	+4.9%	3.84%
RGNX	REGENXBIO Inc. Healthcare	Held	4,368,804	0	$36,610,577	−41.8%	2.42%
STTK	Shattuck Labs, Inc. Healthcare	Held	5,539,724	0	$35,620,425	+76.2%	2.36%
BEAM	Beam Therapeutics Inc. Healthcare	Reduced	1,237,659	-48,200	$29,493,413	−17.3%	1.95%
NGNE	Neurogene Inc. Healthcare	Held	1,459,599	0	$29,425,515	−2.1%	1.95%
COGT	Cogent Biosciences, Inc. Healthcare	Reduced	688,036	-749,882	$26,482,505	−48.1%	1.75%
ABSI	Absci Corp Healthcare	Held	8,253,316	0	$24,759,948	−14.0%	1.64%
IDYA	IDEAYA Biosciences, Inc. Healthcare	Reduced	521,117	-220,900	$17,363,618	−32.3%	1.15%
ALXO	Alx Oncology Holdings Inc Healthcare	Added	7,964,188	+4,699,470	$15,968,196	+332.8%	1.06%
FATE	Fate Therapeutics Inc Healthcare	Held	12,872,946	0	$15,447,535	+22.4%	1.02%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Added	262,674	+128,792	$15,274,493	+154.5%	1.01%
SLDB	Solid Biosciences Inc. Healthcare	Added	2,011,895	+151,353	$14,485,644	+38.0%	0.96%
NUVB	Nuvation Bio Inc. Healthcare	Reduced	3,153,256	-10,000	$13,527,468	−52.3%	0.90%
ZYME	Zymeworks Inc. Healthcare	Held	491,654	0	$12,311,016	−4.9%	0.82%
SLN	Silence Therapeutics plc Healthcare	Held	2,164,777	0	$11,408,374	−13.3%	0.76%
DBVT	DBV Technologies S.A. Healthcare	Reduced	491,340	-58,500	$10,264,092	−2.6%	0.68%
BMRN	Biomarin Pharmaceutical Inc Healthcare	NEW	173,859	NEW	$9,821,294	NEW	0.65%
CLDX	Celldex Therapeutics, Inc. Healthcare	Reduced	261,508	-21,800	$8,295,033	+7.8%	0.55%
CBLL	Ceribell, Inc. Healthcare	Reduced	386,786	-48,453	$7,089,787	−25.7%	0.47%
LIVN	LivaNova PLC Healthcare	Reduced	108,354	-9,700	$6,886,980	−5.2%	0.46%
ESTA	Establishment Labs Holdings Inc. Healthcare	Reduced	103,464	-9,200	$5,874,685	−28.5%	0.39%
PRME	Prime Medicine, Inc. Healthcare	NEW	1,590,832	NEW	$5,536,095	NEW	0.37%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	Reduced	415,710	-32,400	$5,267,045	+43.7%	0.35%
EPRX	Eupraxia Pharmaceuticals Inc. Healthcare	NEW	700,000	NEW	$5,068,000	NEW	0.34%
ARDX	Ardelyx, Inc. Healthcare	NEW	733,350	NEW	$4,392,766	NEW	0.29%
IVVD	Invivyd, Inc. Healthcare	Reduced	2,648,659	-32,500	$3,443,256	−48.0%	0.23%
ATRA	Atara Biotherapeutics, Inc. Healthcare	Held	441,701	0	$2,089,245	−73.9%	0.14%
AGMB	Agomab Therapeutics NV Healthcare	NEW	156,250	NEW	$1,639,062	NEW	0.11%
PLRX	Pliant Therapeutics, Inc. Healthcare	Reduced	772,126	-844,102	$972,878	−50.7%	0.06%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.