Redmile Group, LLC

CIK

1425738

Location

Larkspur, CA

Portfolio Value

Mid $1,510,149,025

Diversification

Diversified

Filing Date

Global Rank

#1,398 / 8,592 ▲ 152

Top Industry

Biotechnology 98.7%

3Y Alpha vs SPY

-13.9%

Period ended 3 months ago

Filed May 15, 2026 · 35d

25 quarters · since Mar 2020

Clone Performance

Jun 2023–Jun 2026 · vs SPY

Hypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.

Cloned portfolio

+22.5%

SPY

+76.8%

Annualised alpha

-13.9%

Max drawdown

−53.8%

Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.

Portfolio Concentration

35 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

29.5%

+12.1 pts

Top 5

66.0%

+5.5 pts

Top 10

81.9%

+2.1 pts

HHI

1,290

Diversified+410

Portfolio Trend

25 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$1,510,149,025	35

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

6 positions

Ticker	Company	Δ Shares	Shares	Value
ALXO	Alx Oncology Holdings Inc	+4,699,470	7,964,188	$15,968,196
ANNX	Annexon, Inc.	+4,499,124	14,549,768	$80,605,714
SRRK	Scholar Rock Holding Corp	+3,845,775	9,066,621	$445,715,088
SLDB	Solid Biosciences Inc.	+151,353	2,011,895	$14,485,644
STOK	Stoke Therapeutics, Inc.	+130,050	4,164,120	$135,583,747
XENE	Xenon Pharmaceuticals Inc.	+128,792	262,674	$15,274,493
No positions match the current search.

Trimmed

Positions the filer reduced

16 positions

Ticker	Company	Δ Shares	Shares	Value
PLRX	Pliant Therapeutics, Inc.	−844,102	772,126	$972,878
COGT	Cogent Biosciences, Inc.	−749,882	688,036	$26,482,505
NRIX	Nurix Therapeutics, Inc.	−361,100	7,732,808	$119,858,524
IDYA	IDEAYA Biosciences, Inc.	−220,900	521,117	$17,363,618
ADCT	ADC Therapeutics SA	−196,229	15,470,502	$58,014,382
IMNM	Immunome Inc.	−159,500	5,558,885	$121,572,814
DBVT	DBV Technologies S.A.	−58,500	491,340	$10,264,092
CBLL	Ceribell, Inc.	−48,453	386,786	$7,089,787
BEAM	Beam Therapeutics Inc.	−48,200	1,237,659	$29,493,413
IVVD	Invivyd, Inc.	−32,500	2,648,659	$3,443,256
ORIC	Oric Pharmaceuticals, Inc.	−32,400	415,710	$5,267,045
CLDX	Celldex Therapeutics, Inc.	−21,800	261,508	$8,295,033
NUVB	Nuvation Bio Inc.	−10,000	3,153,256	$13,527,468
LIVN	LivaNova PLC	−9,700	108,354	$6,886,980
ESTA	Establishment Labs Holdings Inc.	−9,200	103,464	$5,874,685
KRYS	Krystal Biotech, Inc.	−4,200	673,505	$173,979,811
No positions match the current search.

New Positions

Positions the filer opened this quarter

5 positions

Ticker	Company	Shares	Value
BMRN	Biomarin Pharmaceutical Inc	173,859	$9,821,294
PRME	Prime Medicine, Inc.	1,590,832	$5,536,095
EPRX	Eupraxia Pharmaceuticals Inc.	700,000	$5,068,000
ARDX	Ardelyx, Inc.	733,350	$4,392,766
AGMB	Agomab Therapeutics NV	156,250	$1,639,062
No positions match the current search.

Sold Out

Positions the filer fully exited

2 positions

Ticker	Company	Shares	Value
REPL	Replimune Group, Inc.	1,099,756	$10,689,628
KLRS	Kalaris Therapeutics, Inc.	82,955	$700,140
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

35 positions · $1,510,149,025 total · as of Mar 31, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
SRRK	Scholar Rock Holding Corp Healthcare	Added	9,066,621	+3,845,775	$445,715,088	+93.8%	29.51%
KRYS	Krystal Biotech, Inc. Healthcare	Reduced	673,505	-4,200	$173,979,811	+4.1%	11.52%
STOK	Stoke Therapeutics, Inc. Healthcare	Added	4,164,120	+130,050	$135,583,747	+5.9%	8.98%
IMNM	Immunome Inc. Healthcare	Reduced	5,558,885	-5,877,885	$121,572,814	−50.5%	8.05%
NRIX	Nurix Therapeutics, Inc. Healthcare	Reduced	7,732,808	-361,100	$119,858,524	−21.9%	7.94%
ANNX	Annexon, Inc. Healthcare	Added	14,549,768	+4,499,124	$80,605,714	+59.8%	5.34%
ADCT	ADC Therapeutics SA Healthcare	Reduced	15,470,502	-196,229	$58,014,382	+4.9%	3.84%
RGNX	REGENXBIO Inc. Healthcare	Held	4,368,804	0	$36,610,577	−41.8%	2.42%
STTK	Shattuck Labs, Inc. Healthcare	Held	5,539,724	0	$35,620,425	+76.2%	2.36%
BEAM	Beam Therapeutics Inc. Healthcare	Reduced	1,237,659	-48,200	$29,493,413	−17.3%	1.95%
NGNE	Neurogene Inc. Healthcare	Held	1,459,599	0	$29,425,515	−2.1%	1.95%
COGT	Cogent Biosciences, Inc. Healthcare	Reduced	688,036	-749,882	$26,482,505	−48.1%	1.75%
ABSI	Absci Corp Healthcare	Held	8,253,316	0	$24,759,948	−14.0%	1.64%
IDYA	IDEAYA Biosciences, Inc. Healthcare	Reduced	521,117	-220,900	$17,363,618	−32.3%	1.15%
ALXO	Alx Oncology Holdings Inc Healthcare	Added	7,964,188	+4,699,470	$15,968,196	+332.8%	1.06%
FATE	Fate Therapeutics Inc Healthcare	Held	12,872,946	0	$15,447,535	+22.4%	1.02%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Added	262,674	+128,792	$15,274,493	+154.5%	1.01%
SLDB	Solid Biosciences Inc. Healthcare	Added	2,011,895	+151,353	$14,485,644	+38.0%	0.96%
NUVB	Nuvation Bio Inc. Healthcare	Reduced	3,153,256	-10,000	$13,527,468	−52.3%	0.90%
ZYME	Zymeworks Inc. Healthcare	Held	491,654	0	$12,311,016	−4.9%	0.82%
SLN	Silence Therapeutics plc Healthcare	Held	2,164,777	0	$11,408,374	−13.3%	0.76%
DBVT	DBV Technologies S.A. Healthcare	Reduced	491,340	-58,500	$10,264,092	−2.6%	0.68%
BMRN	Biomarin Pharmaceutical Inc Healthcare	NEW	173,859	NEW	$9,821,294	NEW	0.65%
CLDX	Celldex Therapeutics, Inc. Healthcare	Reduced	261,508	-21,800	$8,295,033	+7.8%	0.55%
CBLL	Ceribell, Inc. Healthcare	Reduced	386,786	-48,453	$7,089,787	−25.7%	0.47%
LIVN	LivaNova PLC Healthcare	Reduced	108,354	-9,700	$6,886,980	−5.2%	0.46%
ESTA	Establishment Labs Holdings Inc. Healthcare	Reduced	103,464	-9,200	$5,874,685	−28.5%	0.39%
PRME	Prime Medicine, Inc. Healthcare	NEW	1,590,832	NEW	$5,536,095	NEW	0.37%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	Reduced	415,710	-32,400	$5,267,045	+43.7%	0.35%
EPRX	Eupraxia Pharmaceuticals Inc. Healthcare	NEW	700,000	NEW	$5,068,000	NEW	0.34%
ARDX	Ardelyx, Inc. Healthcare	NEW	733,350	NEW	$4,392,766	NEW	0.29%
IVVD	Invivyd, Inc. Healthcare	Reduced	2,648,659	-32,500	$3,443,256	−48.0%	0.23%
ATRA	Atara Biotherapeutics, Inc. Healthcare	Held	441,701	0	$2,089,245	−73.9%	0.14%
AGMB	Agomab Therapeutics NV Healthcare	NEW	156,250	NEW	$1,639,062	NEW	0.11%
PLRX	Pliant Therapeutics, Inc. Healthcare	Reduced	772,126	-844,102	$972,878	−50.7%	0.06%