EWTX · Edgewise Therapeutics, Inc. · Shareholders & Ownership
Every disclosed holder of EWTX in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.
Who Owns EWTX
13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positionsNo chart: the summed disclosures exceed shares outstanding, so they are not parts of one whole.
| Holder group | Shares | % Out |
|---|---|---|
| Institutional (13F) | 119,907,205 | 110.41% |
| Insiders (Forms 3, 4, 5) | 696,900 | 0.64% |
| 13D/G-only blocks | 13,265,945 | 12.22% |
| Remaining | 25,265,921 | -23.26% |
| Registered funds (N-PORT, not summed) | 26,116,703 | 24.05% |
Shares outstanding: 108,604,129, the issuer's latest cover-page count restated onto today's split basis.
Remaining is negative: the summed disclosures exceed shares outstanding, as when filings are dated at different times or holders that do not disclose their links count the same shares. It is flagged, not clipped.
13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.
Holders of EWTX
| # | Holder | Shares | As of | Notes |
|---|---|---|---|---|
| 1 |
ORBIMED ADVISORS LLC
13F
CIK 1055951 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
15,518,492 | ||
| 1.1 |
|
443,792 | ||
| 2 |
Paradigm Biocapital Advisors LP
13F
CIK 1855655 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
10,215,455 | ||
| 2.1 |
Paradigm Biocapital Advisors LP
13G
CIK 1855655 · Registered investment adviser · Jun 30, 2026
Rule 13d-1(c), passive investor, not summed
|
10,215,455 | ||
| 3 |
RA CAPITAL MANAGEMENT, L.P.
13F
CIK 1346824 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
8,392,730 | ||
| 3.1 |
RA CAPITAL MANAGEMENT, L.P.
13G
CIK 1346824 · Registered investment adviser · Jun 30, 2026
Rule 13d-1(c), passive investor, not summed
|
8,392,730 | ||
| 4 |
BlackRock, Inc.
13F
CIK 2012383 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
|
6,606,336 | ||
| 4.1 |
iShares Russell 2000 ETF
Fund
S000004344 · Registered fund · Jun 30, 2026
iShares Trust, not summed
|
1,835,831 | ||
| 4.2 |
iShares Russell 2000 Growth ETF
Fund
S000004343 · Registered fund · Jun 30, 2026
iShares Trust, not summed
|
660,219 | ||
| 4.3 |
iShares Biotechnology ETF
Fund
S000004350 · Registered fund · Jun 30, 2026
iShares Trust, not summed
|
556,093 | ||
| 4.4 |
iShares U.S. Pharmaceuticals ETF
Fund
S000009417 · Registered fund · Jun 30, 2026
iShares Trust, not summed
|
195,894 | ||
| 4.5 |
Master Small Cap Index Series
Fund
S000002716 · Registered fund · Jun 30, 2026
Quantitative Master Series LLC, not summed
|
130,856 | ||
| 5 |
Jupiter Topco LLC
13F
CIK 2146052 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
6,075,331 | ||
| 6 |
FMR LLC
13F
CIK 315066 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
|
5,489,135 | ||
| 6.1 |
FMR LLC
13G
CIK 315066 · Holding company · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
|
5,489,135 | ||
| 6.2 |
Strategic Advisers Fidelity U.S. Total Stock Fund
Fund
S000061481 · Registered fund · May 31, 2026
Fidelity Rutland Square Trust II, not summed
|
1,940,531 | ||
| 6.3 |
Fidelity Small Cap Index Fund
Fund
S000033638 · Registered fund · Jul 31, 2026
Fidelity Salem Street Trust, not summed
|
782,053 | ||
| 6.4 |
Select Biotechnology Portfolio
Fund
S000007486 · Registered fund · May 31, 2026
Fidelity Select Portfolios, not summed
|
699,425 | ||
| 6.5 |
Fidelity Small Cap Growth Fund
Fund
S000007193 · Registered fund · Jul 31, 2026
Fidelity Securities Fund, not summed
|
642,530 | ||
| 7 |
NOVO HOLDINGS A/S
13F
CIK 1388325 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
5,350,000 | ||
| 8 |
JANUS HENDERSON GROUP PLC
13G
CIK 1274173 · Investment adviser · Mar 31, 2025
Rule 13d-1(b), qualified institution
|
5,282,154 | ||
| 9 |
Driehaus Capital Management LLC
13F
CIK 938206 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
4,728,623 | ||
| 9.1 |
Driehaus Small Cap Growth Fund
Fund
S000058261 · Registered fund · Jun 30, 2026
Driehaus Mutual Funds, not summed
|
522,169 | ||
| 9.2 |
Driehaus Micro Cap Growth Fund
Fund
S000042829 · Registered fund · Jun 30, 2026
Driehaus Mutual Funds, not summed
|
206,555 | ||
| 10 |
Deerfield Management Company, L.P.
13G
CIK 1352546 · Unknown · Jan 23, 2024
Rule 13d-1(c), passive investor
|
4,478,592 | ||
| 11 |
PERCEPTIVE ADVISORS LLC
13F
CIK 1224962 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
4,373,974 | ||
| 12 |
VANGUARD CAPITAL MANAGEMENT LLC
13F
CIK 2100119 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
3,860,670 | ||
| 13 |
BAKER BROS. ADVISORS LP
13F
CIK 1263508 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
3,701,719 | ||
| 13.1 |
BAKER BROS. ADVISORS LP
13G
CIK 1263508 · Registered investment adviser · Jun 30, 2026
Rule 13d-1(b), qualified institution, not summed
|
3,701,719 | ||
| 14 |
|
3,505,199 | ||
| 15 |
Siren, L.L.C.
13F
CIK 2005245 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
3,184,629 | ||
| 16 |
VANGUARD TOTAL STOCK MARKET INDEX FUND
Fund
S000002848 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
|
2,902,230 | ||
| 17 |
Cormorant Asset Management, LP
13F
CIK 1583977 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
2,510,000 | ||
| 18 |
GEODE CAPITAL MANAGEMENT, LLC
13F
CIK 1214717 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
2,174,051 | ||
| 19 |
ALLIANCEBERNSTEIN L.P.
13F
CIK 1109448 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
2,119,024 | ||
| 19.1 |
AB Small Cap Growth Portfolio
Fund
S000010309 · Registered fund · Jun 30, 2026
AB CAP FUND, INC., not summed
|
533,585 | ||
| 19.2 |
AB DISCOVERY GROWTH FUND, INC.
Fund
S000010117 · Registered fund · Jun 30, 2026
AB DISCOVERY GROWTH FUND, INC., not summed
|
489,862 | ||
| 19.3 |
Small Cap Core Portfolio
Fund
S000051867 · Registered fund · Jun 30, 2026
Bernstein Fund Inc, not summed
|
64,100 | ||
| 19.4 |
AB Small Cap Growth Portfolio
Fund
S000010435 · Registered fund · Jun 30, 2026
AB VARIABLE PRODUCTS SERIES FUND, INC., not summed
|
10,213 | ||
| 19.5 |
Tax-Aware Overlay A Portfolio
Fund
S000027648 · Registered fund · Jun 30, 2026
BERNSTEIN SANFORD C FUND INC, not summed
|
3,388 | ||
| 20 |
Integral Health Asset Management, LLC
13F
CIK 1773206 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
2,000,000 | ||
| 21 |
BRAIDWELL LP
13F
CIK 1920938 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,996,965 | ||
| 22 |
MORGAN STANLEY
13F
CIK 895421 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,948,597 | ||
| 22.1 |
E*TRADE No Fee Total Market Index Fund
Fund
S000090722 · Registered fund · Jul 31, 2026
E Trade Trust, not summed
|
30 | ||
| 23 |
|
1,827,927 | ||
| 23.1 |
State Street(R) SPDR(R) S&P(R) Pharmaceuticals ETF
Fund
S000012321 · Registered fund · Jun 30, 2026
SPDR SERIES TRUST, not summed
|
198,593 | ||
| 23.2 |
STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO
Fund
S000050332 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
|
23,941 | ||
| 23.3 |
State Street Total Return V.I.S. Fund
Fund
S000001637 · Registered fund · Jun 30, 2026
STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed
|
1,806 | ||
| 23.4 |
State Street Balanced Index Fund
Fund
S000082802 · Registered fund · Jun 30, 2026
STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
|
349 | ||
| 24 |
MPM BIOIMPACT LLC
13F
CIK 1687078 · Investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,620,780 | ||
| 25 |
BANK OF AMERICA CORP /DE/
13F
CIK 70858 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,558,260 | ||
| 26 |
Qube Research & Technologies Ltd
13F
CIK 1729829 · Exempt reporting adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,252,507 | ||
| 27 |
DIMENSIONAL FUND ADVISORS LP
13F
CIK 354204 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,139,726 | ||
| 27.1 |
U.S. SMALL CAP PORTFOLIO
Fund
S000000971 · Registered fund · Jul 31, 2026
DFA INVESTMENT DIMENSIONS GROUP INC, not summed
|
269,017 | ||
| 27.2 |
U.S. MICRO CAP PORTFOLIO
Fund
S000000948 · Registered fund · Jul 31, 2026
DFA INVESTMENT DIMENSIONS GROUP INC, not summed
|
259,486 | ||
| 27.3 |
Dimensional U.S. Small Cap ETF
Fund
S000070906 · Registered fund · Jul 31, 2026
Dimensional ETF Trust, not summed
|
168,775 | ||
| 27.4 |
Dimensional U.S. Core Equity 2 ETF
Fund
S000070903 · Registered fund · Jul 31, 2026
Dimensional ETF Trust, not summed
|
103,617 | ||
| 27.5 |
U.S. CORE EQUITY 2 PORTFOLIO
Fund
S000000980 · Registered fund · Jul 31, 2026
DFA INVESTMENT DIMENSIONS GROUP INC, not summed
|
32,875 | ||
| 28 |
AMERICAN CENTURY COMPANIES INC
13F
CIK 748054 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,127,078 | ||
| 28.1 |
Small Cap Growth Fund
Fund
S000006193 · Registered fund · Jul 31, 2026
American Century Mutual Funds, Inc., not summed
|
856,214 | ||
| 29 |
First Light Asset Management, LLC
13F
CIK 1600004 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
1,095,171 | ||
| 30 |
VICTORY CAPITAL MANAGEMENT INC
13F
CIK 1040188 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
902,870 | ||
| 30.1 |
Victory Pioneer Select Mid Cap Growth Fund
Fund
S000089755 · Registered fund · May 31, 2026
Victory Portfolios IV, not summed
|
795,789 | ||
| 30.2 |
Victory Small Cap Stock Fund
Fund
S000012914 · Registered fund · Jul 31, 2026
Victory Portfolios III, not summed
|
49,713 | ||
| 30.3 |
Victory Pioneer Select Mid Cap Growth VCT Portfolio
Fund
S000089715 · Registered fund · Jun 30, 2026
Victory Variable Insurance Funds II, not summed
|
47,711 | ||
| 30.4 |
Victory Extended Market Index Fund
Fund
S000012941 · Registered fund · Jul 31, 2026
Victory Portfolios III, not summed
|
9,072 | ||
| 31 |
VANGUARD EXTENDED MARKET INDEX FUND
Fund
S000002841 · Registered fund · Jun 30, 2026
VANGUARD INDEX FUNDS, not summed
|
864,638 | ||
| 32 |
PRICE T ROWE ASSOCIATES INC /MD/
13F
CIK 80255 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
816,518 | ||
| 32.1 |
T. Rowe Price Integrated U.S. Small-Cap Growth Equity Fund
Fund
S000002074 · Registered fund · Jun 30, 2026
T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC., not summed
|
300,100 | ||
| 32.2 |
T. Rowe Price New Horizons Fund, Inc.
Fund
S000002106 · Registered fund · Jun 30, 2026
T. ROWE PRICE NEW HORIZONS FUND, INC., not summed
|
233,600 | ||
| 32.3 |
T. Rowe Price Small-Cap Index Fund
Fund
S000051327 · Registered fund · Jun 30, 2026
T. ROWE PRICE INDEX TRUST, INC., not summed
|
10,786 | ||
| 33 |
VANGUARD PORTFOLIO MANAGEMENT LLC
13F
CIK 2100121 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
786,456 | ||
| 34 |
Assenagon Asset Management S.A.
13F
CIK 1546007 · Unknown · Sep 30, 2026
|
735,202 | ||
| 35 |
Janus Henderson Global Life Sciences Fund
Fund
S000010494 · Registered fund · Jun 30, 2026
Janus Investment Fund, not summed
|
677,076 | ||
| 36 |
NORTHERN TRUST CORP
13F
CIK 73124 · Bank · Jun 30, 2026
carried, not yet filed for the newest quarter
|
671,270 | ||
| 37 |
Aberdeen Group plc
13F
CIK 1716774 · Holding company · Jun 30, 2026
carried, not yet filed for the newest quarter
|
647,926 | ||
| 38 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
CIK 884546 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
620,532 | ||
| 39 |
Tyro Capital Management LLC
13F
CIK 1915395 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
612,965 | ||
| 40 |
GOLDMAN SACHS GROUP INC
13F
CIK 886982 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
599,469 | ||
| 40.1 |
Goldman Sachs Small Cap Growth Insights Fund
Fund
S000014930 · Registered fund · Jul 31, 2026
Goldman Sachs Trust, not summed
|
10,550 | ||
| 40.2 |
Goldman Sachs Small Cap Equity Insights Fund
Fund
S000009329 · Registered fund · Jul 31, 2026
Goldman Sachs Trust, not summed
|
5,975 | ||
| 40.3 |
Goldman Sachs Absolute Return Tracker Fund
Fund
S000020314 · Registered fund · Jun 30, 2026
GOLDMAN SACHS TRUST, not summed
|
381 | ||
| 41 |
Parkman Healthcare Partners LLC
13F
CIK 1777015 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
577,036 | ||
| 42 |
Artisan Partners Limited Partnership
13F
CIK 1466153 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
574,925 | ||
| 42.1 |
Artisan International Small-Mid Fund
Fund
S000006494 · Registered fund · Jun 30, 2026
Artisan Partners Funds Inc., not summed
|
328,745 | ||
| 43 |
VANGUARD FIDUCIARY TRUST CO
13F
CIK 933478 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
548,285 | ||
| 44 |
NORGES BANK
13F
CIK 1374170 · Non-US institution · Jun 30, 2026
carried, not yet filed for the newest quarter
|
510,140 | ||
| 45 |
Opaleye Management Inc.
13F
CIK 1595855 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
500,000 | ||
| 46 |
Janus Henderson Triton Fund
Fund
S000010485 · Registered fund · Jun 30, 2026
Janus Investment Fund, not summed
|
471,394 | ||
| 47 |
CITADEL ADVISORS LLC
13F
CIK 1423053 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
469,707 | ||
| 48 |
ADAGE CAPITAL PARTNERS GP, L.L.C.
13F
CIK 1165408 · Registered investment adviser · Jun 30, 2026
carried, not yet filed for the newest quarter
|
462,000 | ||
| 49 |
Soleus Capital Management, L.P.
13F
CIK 1802630 · Unknown · Jun 30, 2026
carried, not yet filed for the newest quarter
|
450,889 | ||
| 50 |
|
443,792 |
44 more nested rows are not shown here; Every filing lists them all.
Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.
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