Affinity Asset Advisors, LLC

CIK

1773195

Location

NEW YORK, NY

Portfolio Value

Mid $2,118,752,888

Diversification

Diversified

Filing Date

Global Rank

#1,288 / 8,700 ▲ 287

Top Industry

Biotechnology 91.6%

Period ended 2 months ago

Filed Aug 13, 2026 · 31d

23 quarters · since Dec 2020

Portfolio Concentration

105 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

6.3%

−1.2 pts

Top 5

26.9%

−1.8 pts

Top 10

42.4%

−3.3 pts

HHI

265

Diversified−32

Portfolio Trend

23 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	98.8%	$2,092,661,888	100
Financial Services	1.2%	$26,091,000	5

Last Quarter's Activity

Export CSV

Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

25 positions

Ticker	Company	Δ Shares	Shares	Value
PRQR	ProQR Therapeutics N.V.	+3,089,658	5,543,936	$10,311,720
EQ	Equillium, Inc.	+2,873,690	4,100,000	$13,120,000
SGMT	Sagimet Biosciences Inc.	+1,629,844	2,497,864	$19,308,488
AVTX	Avalo Therapeutics, Inc.	+1,559,160	2,900,000	$53,592,000
CATX	Perspective Therapeutics, Inc.	+1,050,000	4,214,582	$14,371,724
ALEC	Alector, Inc.	+1,010,000	1,510,000	$3,035,100
SABS	SAB Biotherapeutics, Inc.	+950,000	1,525,000	$5,947,500
ROIV	Roivant Sciences Ltd.	+950,000	3,750,000	$132,712,500
IBIO	iBio, Inc.	+900,681	4,007,881	$7,013,791
LXEO	Lexeo Therapeutics, Inc.	+757,400	5,807,611	$27,034,429
TSHA	Taysha Gene Therapies, Inc.	+750,000	1,750,000	$11,917,500
MGNX	Macrogenics Inc	+716,606	1,216,606	$5,620,719
RLAY	Relay Therapeutics, Inc.	+650,000	1,050,000	$19,645,500
ANRO	Alto Neuroscience, Inc.	+350,000	850,000	$22,431,500
CLYM	Climb Bio, Inc.	+272,000	972,000	$12,674,880
JBIO	Jade Biosciences, Inc.	+200,394	840,350	$18,672,577
CLDX	Celldex Therapeutics, Inc.	+200,000	700,000	$26,047,000
MRNA	Moderna, Inc.	+175,000	975,000	$68,279,250
INSM	INSMED Inc	+170,000	650,000	$69,303,000
—		+133,501	1,145,391	$24,339,558
STRO	Sutro Biopharma, Inc.	+102,968	1,172,487	$38,926,568
BLTE	Belite Bio, Inc	+100,000	165,000	$25,407,525
CGEM	Cullinan Therapeutics, Inc.	+94,500	875,760	$15,947,589
ORKA	Oruka Therapeutics, Inc.	+90,327	590,000	$56,150,300
QURE	uniQure N.V.	+75,000	375,000	$17,272,500
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
ZURA	Zura Bio Ltd	−1,100,000	1,464,303	$8,639,387
TEVA	Teva Pharmaceutical Industries Ltd	−1,026,000	374,000	$12,671,120
CMPS	COMPASS Pathways plc	−807,300	301,183	$4,261,739
RZLT	Rezolute, Inc.	−547,641	1,000,000	$5,200,000
OVID	Ovid Therapeutics Inc.	−491,756	10,144,562	$27,288,871
OBIO	Orchestra BioMed Holdings, Inc.	−369,150	33,400	$144,121
COGT	Cogent Biosciences, Inc.	−300,000	450,000	$17,415,000
APGE	Apogee Therapeutics, Inc.	−297,926	987,000	$131,004,510
TRVI	Trevi Therapeutics, Inc.	−200,000	1,800,172	$33,573,207
NXTC	NextCure, Inc.	−199,866	41,960	$67,136
KPTI	Karyopharm Therapeutics Inc.	−187,500	312,500	$3,053,125
CYTK	Cytokinetics Inc	−150,483	550,000	$46,854,500
SGP	SpyGlass Pharma, Inc.	−118,414	131,586	$2,929,104
ANAB	Anaptysbio, Inc	−113,891	826,109	$55,762,357
ERAS	Erasca, Inc.	−100,000	5,250,000	$96,180,000
ELVN	Enliven Therapeutics, Inc.	−86,904	500,000	$25,375,000
XENE	Xenon Pharmaceuticals Inc.	−80,000	1,595,000	$96,274,200
MBX	MBX Biosciences, Inc.	−75,000	75,000	$4,140,000
ABVX	Abivax S.A.	−75,000	330,000	$43,975,800
ASND	Ascendis Pharma A/S	−65,000	30,000	$8,001,600
TYRA	Tyra Biosciences, Inc.	−57,500	200,012	$6,388,383
ARWR	Arrowhead Pharmaceuticals, Inc.	−50,000	150,000	$12,226,500
AVBP	ArriVent BioPharma, Inc.	−50,000	125,000	$4,342,500
CRSP	CRISPR Therapeutics AG	−50,000	100,000	$5,454,000
—		−25,000	275,000	$0
No positions match the current search.

New Positions

Positions the filer opened this quarter

20 positions

Ticker	Company	Shares	Value
TRAX	First Tracks Biotherapeutics, Inc.	2,032,012	$40,884,081
LLY	ELI LILLY & Co	20,000	$23,988,602
IDYA	IDEAYA Biosciences, Inc.	400,000	$14,908,000
ODTX	Odyssey Therapeutics, Inc.	766,346	$14,338,333
OMER	Omeros Corp	1,411,300	$13,421,463
EVMN	Evommune, Inc.	500,100	$6,646,329
ASMB	Assembly Biosciences, Inc.	190,000	$5,221,200
COAG	Hemab Therapeutics Holdings, Inc.	138,030	$5,069,841
RACC	Research Alliance Corp III	370,000	$3,959,000
AMAN	Amanat Acquisition Corp.	375,000	$3,810,000
BHVN	Biohaven Ltd.	250,000	$3,720,000
FTH	Faeth Therapeutics, Inc.	144,404	$3,610,100
JATT	JATT II Acquisition Corp.	200,000	$2,272,000
NMRA	Neumora Therapeutics, Inc.	1,070,651	$1,820,106
AMLX	Amylyx Pharmaceuticals, Inc.	98,999	$1,778,022
SPRB	Spruce Biosciences, Inc.	30,000	$1,620,000
SMMT	Summit Therapeutics Inc.	100,000	$1,457,000
EIKN	Eikon Therapeutics, Inc.	98,001	$1,278,913
BOLD	Boundless Bio, Inc.	250,000	$625,000
RCKT	Rocket Pharmaceuticals, Inc.	75,000	$0
No positions match the current search.

Sold Out

Positions the filer fully exited

13 positions

Ticker	Company	Shares	Value
SPY	Spdr S&P 500 ETF Trust	200,000	$130,068,000
BMY	Bristol Myers Squibb Co	300,000	$18,195,000
BBIO	BridgeBio Pharma, Inc.	150,000	$11,139,000
WVE	Wave Life Sciences, Inc.	1,401,727	$10,162,520
IBRX	ImmunityBio, Inc.	1,250,000	$9,587,500
NVO	Novo Nordisk A S	175,000	$6,431,250
CGON	CG Oncology, Inc.	60,000	$4,060,800
CELC	Celcuity Inc.	30,000	$3,424,200
CORT	Corcept Therapeutics Inc	50,000	$2,015,500
—		362,764	$0
—		562,631	$0
—		229,076	$0
CNTA	Centessa Pharmaceuticals plc	1,400,000	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

105 tracked positions · $2,118,752,888 total · filing declares 113 positions · $2,212,480,490 · as of Jun 30, 2026

All sectors Financial Services Healthcare

Showing 1–50 of 105 positions by value · page 1 of 3

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
ROIV	Roivant Sciences Ltd. Healthcare	Added	3,750,000	+950,000	$132,712,500	+71.1%	6.26%
APGE	Apogee Therapeutics, Inc. Healthcare	Reduced	987,000	-297,926	$131,004,510	+21.1%	6.18%
SYRE	Spyre Therapeutics, Inc. Healthcare	Held	1,279,134	0	$113,561,516	+76.0%	5.36%
XENE	Xenon Pharmaceuticals Inc. Healthcare	Reduced	1,595,000	-80,000	$96,274,200	−1.2%	4.54%
ERAS	Erasca, Inc. Healthcare	Reduced	5,250,000	-100,000	$96,180,000	+11.1%	4.54%
ALKS	Alkermes plc. CALL + SHARES Healthcare	Added	1,375,000	+25,000	$72,050,000	+50.9%	3.40%
INSM	INSMED Inc Healthcare	Added	650,000	+170,000	$69,303,000	−11.7%	3.27%
MRNA	Moderna, Inc. PUT CALL Healthcare	Added	975,000	+175,000	$68,279,250	+68.0%	3.22%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Added	185,000	+15,000	$61,936,150	+13.1%	2.92%
ORKA	Oruka Therapeutics, Inc. Healthcare	Added	590,000	+90,327	$56,150,300	+129.1%	2.65%
ANAB	Anaptysbio, Inc Healthcare	Reduced	826,109	-113,891	$55,762,357	+7.0%	2.63%
AVTX	Avalo Therapeutics, Inc. Healthcare	Added	2,900,000	+1,559,160	$53,592,000	+167.7%	2.53%
CYTK	Cytokinetics Inc Healthcare	Reduced	550,000	-150,483	$46,854,500	+1.5%	2.21%
RVMD	Revolution Medicines, Inc. Healthcare	Added	250,000	+50,000	$46,820,000	+140.7%	2.21%
ABVX	Abivax S.A. Healthcare	Reduced	330,000	-75,000	$43,975,800	−2.5%	2.08%
TRAX	First Tracks Biotherapeutics, Inc. Healthcare	NEW	2,032,012	NEW	$40,884,081	NEW	1.93%
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	Held	400,000	0	$38,992,000	+16.2%	1.84%
STRO	Sutro Biopharma, Inc. Healthcare	Added	1,172,487	+102,968	$38,926,568	+46.1%	1.84%
TRVI	Trevi Therapeutics, Inc. Healthcare	Reduced	1,800,172	-200,000	$33,573,207	+40.7%	1.58%
OVID	Ovid Therapeutics Inc. Healthcare	Reduced	10,144,562	-491,756	$27,288,871	+15.6%	1.29%
LXEO	Lexeo Therapeutics, Inc. Healthcare	Added	5,807,611	+757,400	$27,034,429	−6.7%	1.28%
CLDX	Celldex Therapeutics, Inc. Healthcare	Added	700,000	+200,000	$26,047,000	+64.2%	1.23%
BLTE	Belite Bio, Inc Healthcare	Added	165,000	+100,000	$25,407,525	+145.2%	1.20%
ELVN	Enliven Therapeutics, Inc. Healthcare	Reduced	500,000	-86,904	$25,375,000	+10.3%	1.20%
		Added	1,145,391	+133,501	$24,339,558	−7.1%	1.15%
LLY	ELI LILLY & Co CALL Healthcare	NEW	20,000	NEW	$23,988,602	NEW	1.13%
NRIX	Nurix Therapeutics, Inc. Healthcare	Held	967,620	0	$23,474,461	+56.5%	1.11%
ANRO	Alto Neuroscience, Inc. Healthcare	Added	850,000	+350,000	$22,431,500	+99.6%	1.06%
MDGL	Madrigal Pharmaceuticals, Inc. Healthcare	Reduced	40,000	-15,000	$21,478,000	−25.4%	1.01%
PTGX	Protagonist Therapeutics, Inc Healthcare	Held	172,125	0	$21,099,082	+16.3%	1.00%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Held	750,000	0	$20,235,000	−0.4%	0.96%
RLAY	Relay Therapeutics, Inc. Healthcare	Added	1,050,000	+650,000	$19,645,500	+393.6%	0.93%
SGMT	Sagimet Biosciences Inc. Healthcare	Added	2,497,864	+1,629,844	$19,308,488	+325.7%	0.91%
JBIO	Jade Biosciences, Inc. Healthcare	Added	840,350	+200,394	$18,672,577	+107.7%	0.88%
COGT	Cogent Biosciences, Inc. Healthcare	Reduced	450,000	-300,000	$17,415,000	−39.7%	0.82%
QURE	uniQure N.V. CALL + SHARES Healthcare	Added	375,000	+75,000	$17,272,500	+252.1%	0.82%
TVTX	Travere Therapeutics, Inc. Healthcare	Held	300,000	0	$17,043,000	+91.2%	0.80%
CGEM	Cullinan Therapeutics, Inc. Healthcare	Added	875,760	+94,500	$15,947,589	+43.6%	0.75%
SVRA	Savara Inc Healthcare	Held	2,512,153	0	$15,474,862	+12.8%	0.73%
IDYA	IDEAYA Biosciences, Inc. Healthcare	NEW	400,000	NEW	$14,908,000	NEW	0.70%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	Held	520,000	0	$14,555,400	+6.1%	0.69%
CATX	Perspective Therapeutics, Inc. Healthcare	Added	4,214,582	+1,050,000	$14,371,724	+8.9%	0.68%
ODTX	Odyssey Therapeutics, Inc. Healthcare	NEW	766,346	NEW	$14,338,333	NEW	0.68%
OMER	Omeros Corp PUT Healthcare	NEW	1,411,300	NEW	$13,421,463	NEW	0.63%
HLXC	Helix Acquisition Corp. III Financial Services	Held	1,250,000	0	$13,300,000	+4.7%	0.63%
EQ	Equillium, Inc. Healthcare	Added	4,100,000	+2,873,690	$13,120,000	+434.9%	0.62%
ESTA	Establishment Labs Holdings Inc. Healthcare	Added	148,013	+48,013	$12,700,995	+123.7%	0.60%
CLYM	Climb Bio, Inc. Healthcare	Added	972,000	+272,000	$12,674,880	+164.3%	0.60%
TEVA	Teva Pharmaceutical Industries Ltd Healthcare	Reduced	374,000	-1,026,000	$12,671,120	−70.0%	0.60%
MANE	Veradermics, Inc Healthcare	Added	100,000	+30,000	$12,294,000	+178.1%	0.58%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.