TLPH · Talphera, Inc.

$1.19 +0.00 (+0.00%) At close · Aug 21

Market Cap

$61.77M

51.91M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 50

Total Value: $24,775,929

Total Shares: 24,054,321

Institutional Ownership Trend

15 quarters

Holder Concentration

Across 50 13F filers · Δ vs Mar 31, 2026

Top Holder

21.5%

+0.4 pts

Top 5

75.5%

+1.2 pts

Top 10

89.3%

+1.6 pts

HHI

1,341

Broadly held+62

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +4

Institutional value: +49.7%

Shares held: +9.0%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Small Rosalind Advisors, Inc.	+1,815,585	5,169,501
Micro Dauntless Investment Group, LLC	+310,817	746,051
Mega VANGUARD CAPITAL MANAGEMENT LLC	+260,266	701,877
Mid Shay Capital LLC	+155,681	405,764
Mega UBS Group AG	+116,092	129,916

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large RENAISSANCE TECHNOLOGIES LLC	−124,455	113,300
Mega CITADEL ADVISORS LLC	−97,851	118,600
Mid AIGH Capital Management LLC	−60,000	4,601,502
Large Caption Management, LLC	−46,851	514,969
Small TWO SIGMA SECURITIES, LLC	−2,875	15,788

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Large Universal- Beteiligungs- und Servicegesellschaft mbH	50,000	$51,500
Mega GOLDMAN SACHS GROUP INC	28,435	$29,288
Mid STEPHENS INC /AR/	15,133	$15,586
Large WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	12,500	$12,875
Mid Virtu Financial LLC	10,142	$10,446

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Micro Empery Asset Management, LP	590,481	$442,860
Mid AlphaCore Capital LLC	20,670	$15,502
Large HRT FINANCIAL LP	19,090	$14,317
Large MAI Capital Management	3,314	$2,485
Mid Tower Research Capital LLC (TRC)	1,145	$858

Filter: New 12 Increased 13 Reduced 7 Sold out 8 Unchanged 18

Showing 54 of 54

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Rosalind Advisors, Inc.

$5,324,586

21.49%

5,169,501

AIGH Capital Management LLC

$4,739,546

19.13%

4,601,502

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Worth Venture Partners, LLC	1,204,013	$1,240,133	26.2%	Other
Held directly	3,397,489	$3,499,413	73.8%	Sole

Rock Springs Capital Management LP

$3,696,861

14.92%

3,589,186

Nantahala Capital Management, LLC

$3,597,294

14.52%

3,492,519

Bleichroeder LP

$1,347,020

5.44%

1,307,787

CANTOR FITZGERALD, L. P.

$914,105

3.69%

887,481

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Cantor Fitzgerald & Co.	887,481	$914,105	100.0%	Defined

Dauntless Investment Group, LLC

$768,432

3.10%

746,051

VANGUARD CAPITAL MANAGEMENT LLC

$722,933

2.92%

701,877

Caption Management, LLC

$530,418

2.14%

514,969

Almitas Capital LLC

$481,166

1.94%

467,152

GEODE CAPITAL MANAGEMENT, LLC

$441,933

1.78%

429,062

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	79,212	$81,588	18.5%	Defined
Held directly	349,850	$360,345	81.5%	Defined

Shay Capital LLC

$417,936

1.69%

405,764

VANGUARD FIDUCIARY TRUST CO

$229,043

0.92%

222,372

GSA CAPITAL PARTNERS LLP

$215,635

0.87%

209,355

DIADEMA PARTNERS LP

$158,169

0.64%

153,563

UBS Group AG

$133,812

0.54%

129,916

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	22	$22	0.0%	Defined
UBS AG	5,600	$5,768	4.3%	Defined
UBS Switzerland AG	7	$7	0.0%	Defined
UBS Europe SE	18	$18	0.0%	Defined
UBS Securities LLC	124,269	$127,997	95.7%	Defined

RENAISSANCE TECHNOLOGIES LLC

$116,699

0.47%

113,300

Mariner, LLC

$103,000

0.42%

100,000

BlackRock, Inc.

$94,294

0.38%

91,548

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BlackRock Institutional Trust Company, N.A.	91,548	$94,294	100.0%	Sole

NORTHERN TRUST CORP

$90,944

0.37%

88,296

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	88,296	$90,944	100.0%	Defined

Values First Advisors, Inc.

$82,075

0.33%

79,685

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$77,961

0.31%

75,691

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	75,691	$77,961	100.0%	Other

CITADEL ADVISORS LLC

$61,594

0.25%

59,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	59,800	$61,594	100.0%	Defined

CITADEL ADVISORS LLC

$60,564

0.24%

58,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	58,800	$60,564	100.0%	Defined

Universal- Beteiligungs- und Servicegesellschaft mbH

$51,500

0.21%

50,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH	50,000	$51,500	100.0%	Defined

Persistent Asset Partners Ltd

$40,137

0.16%

38,968

Vanguard Global Advisers, LLC

$30,550

0.12%

29,661

GOLDMAN SACHS GROUP INC

$29,288

0.12%

28,435

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	28,435	$29,288	100.0%	Defined

JANE STREET GROUP, LLC

$29,149

0.12%

28,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	28,300	$29,149	100.0%	Defined

XTX Topco Ltd

$29,039

0.12%

28,194

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	28,194	$29,039	100.0%	Defined

STATE STREET CORP

$22,847

0.09%

22,182

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS TRUST COMPANY	22,182	$22,847	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$22,660

0.09%

22,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	22,000	$22,660	100.0%	Other

JANE STREET GROUP, LLC

$20,085

0.08%

19,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	19,500	$20,085	100.0%	Defined

TWO SIGMA SECURITIES, LLC

$16,261

0.07%

15,788

STEPHENS INC /AR/

$15,586

0.06%

15,133

WEALTH ENHANCEMENT ADVISORY SERVICES, LLC

$12,875

0.05%

12,500

Onyx Bridge Wealth Group LLC

$11,845

0.05%

11,500

JANE STREET GROUP, LLC

$10,973

0.04%

10,654

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	10,654	$10,973	100.0%	Defined

Virtu Financial LLC

$10,446

0.04%

10,142

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Virtu Americas LLC	10,142	$10,446	100.0%	Defined

GROUP ONE TRADING LLC

$8,459

0.03%

8,213

JPMORGAN CHASE & CO

$4,680

0.02%

4,544

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Securities LLC	4,544	$4,680	100.0%	Defined

Steward Partners Investment Advisory, LLC

$1,030

0.00%

1,000

BARCLAYS PLC

$989

0.00%

961

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS CAPITAL INC.	961	$989	100.0%	Defined

WELLS FARGO & COMPANY/MN

$618

0.00%

600

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO CLEARING SERVICES, LLC	600	$618	100.0%	Defined

OSAIC HOLDINGS, INC.

$293

0.00%

285

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	285	$293	100.0%	Defined

NewEdge Advisors, LLC

$207

0.00%

201

BNP PARIBAS ARBITRAGE, SA

$140

0.00%

136

SBI Securities Co., Ltd.

$118

0.00%

115

Arax Advisory Partners

$83

0.00%

Larson Financial Group LLC

$30

0.00%

MORGAN STANLEY

$10

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY SMITH BARNEY LLC	10	$10	100.0%	Defined

BESSEMER GROUP INC

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BESSEMER TRUST Co NATIONAL ASSOCIATION	5	$5	100.0%	Defined

FLAGSHIP WEALTH ADVISORS, LLC

0.00%

Global Retirement Partners, LLC

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	1,145	$858	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STRATEGIC ADVISERS LLC	50	$37	100.0%	Defined

Key facts CIK 1427925 CUSIP 00444T209 13F (30d) 50 filings 49 filers Visit website Investor relations