Exome Asset Management LLC
Filing Date
Global Rank
#4,228
/ 8,232
▼ 94
Top Industry
Biotechnology
71.3%
3Y Alpha vs SPY
+10.5%
Period ended 2 months ago
Filed May 15, 2026 · 30d
10 quarters · since Dec 2023
Clone Performance
Feb 2024–Jun 2026 · vs SPYHypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.
Cloned portfolio
+86.0%
SPY
+52.9%
Annualised alpha
+10.5%
Max drawdown
−33.0%
Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.
Portfolio Concentration
45 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
8.6%
−0.1 pts
Top 5
29.4%
+1.1 pts
Top 10
46.5%
+1.1 pts
HHI
340
Diversified+24
Portfolio Trend
10 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $169,964,515 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
4 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| VSTM | Verastem, Inc. | +234,957 | 636,700 | $3,374,510 | |
| CRBP | Corbus Pharmaceuticals Holdings, Inc. | +94,593 | 234,136 | $2,198,537 | |
| NBP | NovaBridge Biosciences | +77,373 | 576,960 | $1,419,321 | |
| UNH | Unitedhealth Group Inc | +7,027 | 12,862 | $3,480,328 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
23 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| ADAG | Adagene Inc. | −323,376 | 736,845 | $2,888,432 | |
| CTMX | CytomX Therapeutics, Inc. | −223,837 | 521,468 | $2,450,899 | |
| PALI | Palisade Bio, Inc. | −158,203 | 600,000 | $1,050,000 | |
| APLS | Apellis Pharmaceuticals, Inc. | −50,332 | 85,517 | $3,440,348 | |
| NXTC | NextCure, Inc. | −49,500 | 115,500 | $1,233,540 | |
| LQDA | Liquidia Corp | −45,352 | 45,796 | $1,728,341 | |
| COGT | Cogent Biosciences, Inc. | −27,035 | 278,533 | $10,720,735 | |
| CYTK | Cytokinetics Inc | −21,031 | 103,718 | $6,836,053 | |
| GH | Guardant Health, Inc. | −15,446 | 82,736 | $7,642,324 | |
| BBIO | BridgeBio Pharma, Inc. | −13,231 | 67,492 | $5,011,955 | |
| ALMS | Alumis Inc. | −13,074 | 279,176 | $6,150,247 | |
| PRAX | Praxis Precision Medicines, Inc. | −12,653 | 45,469 | $14,649,657 | |
| AGIO | Agios Pharmaceuticals, Inc. | −11,882 | 125,060 | $4,230,779 | |
| GKOS | GLAUKOS Corp | −10,597 | 20,874 | $2,247,294 | |
| TXG | 10x Genomics, Inc. | −9,464 | 154,194 | $3,273,538 | |
| VERA | Vera Therapeutics, Inc. | −9,400 | 114,991 | $4,626,087 | |
| IONS | Ionis Pharmaceuticals Inc | −6,451 | 110,064 | $8,264,705 | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | −4,037 | 45,721 | $2,866,706 | |
| PEN | Penumbra Inc | −2,700 | 6,300 | $2,068,731 | |
| ELV | Elevance Health, Inc. | −2,514 | 14,677 | $4,296,691 | |
| ELVN | Enliven Therapeutics, Inc. | −2,217 | 220,091 | $8,627,567 | |
| LLY | ELI LILLY & Co | −840 | 7,012 | $6,449,427 | |
| UTHR | UNITED THERAPEUTICS Corp | −632 | 7,053 | $4,182,287 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
14 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| INSM | INSMED Inc | 26,651 | $4,357,971 | |
| MLTX | MoonLake Immunotherapeutics | 215,376 | $4,014,608 | |
| RYTM | Rhythm Pharmaceuticals, Inc. | 40,581 | $3,529,329 | |
| BSX | Boston Scientific Corp | 48,347 | $3,033,774 | |
| ALKS | Alkermes plc. | 84,103 | $2,973,882 | |
| GLUE | Monte Rosa Therapeutics, Inc. | 179,484 | $2,952,511 | |
| CBIO | Crescent Biopharma, Inc. | 153,191 | $2,814,118 | |
| RLAY | Relay Therapeutics, Inc. | 278,302 | $2,769,104 | |
| MAZE | Maze Therapeutics, Inc. | 88,510 | $2,642,023 | |
| AVTX | Avalo Therapeutics, Inc. | 159,341 | $2,378,961 | |
| SLNO | Soleno Therapeutics Inc | 61,673 | $2,064,812 | |
| ZBIO | Zenas BioPharma, Inc. | 80,730 | $1,578,271 | |
| FDMT | 4D Molecular Therapeutics, Inc. | 130,564 | $1,215,550 | |
| LPCN | Lipocine Inc. | 60,861 | $486,279 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
20 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| WVE | Wave Life Sciences Ltd. | 421,488 | $7,165,296 | |
| JAZZ | Jazz Pharmaceuticals plc | 26,494 | $4,503,980 | |
| IMVT | Immunovant, Inc. | 158,622 | $4,032,171 | |
| UHS | Universal Health Services Inc | 17,628 | $3,843,256 | |
| IRON | Disc Medicine, Inc. | 46,743 | $3,711,861 | |
| CELC | Celcuity Inc. | 34,289 | $3,419,984 | |
| TVTX | Travere Therapeutics, Inc. | 89,052 | $3,402,676 | |
| DXCM | Dexcom Inc | 50,147 | $3,328,256 | |
| IMCR | Immunocore Holdings plc | 76,750 | $2,663,992 | |
| EWTX | Edgewise Therapeutics, Inc. | 100,046 | $2,482,641 | |
| BLTE | Belite Bio, Inc | 14,328 | $2,291,906 | |
| WAY | Waystar Holding Corp. | 68,969 | $2,258,734 | |
| IRWD | Ironwood Pharmaceuticals Inc | 648,532 | $2,185,552 | |
| KPTI | Karyopharm Therapeutics Inc. | 295,541 | $2,175,181 | |
| UPB | Upstream Bio, Inc. | 64,845 | $1,760,541 | |
| GOSS | Gossamer Bio, Inc. | 451,699 | $1,400,266 | |
| IKT | Inhibikase Therapeutics, Inc. | 600,000 | $1,230,000 | |
| IQV | Iqvia Holdings Inc. | 5,378 | $1,212,254 | |
| THC | Tenet Healthcare Corp | 6,084 | $1,209,012 | |
| FULC | Fulcrum Therapeutics, Inc. | 92,055 | $1,041,142 | |
| No positions match the current search. | ||||
45 positions ·
$169,964,515 total
· as of Mar 31, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| PRAX |
Praxis Precision Medicines, Inc.
Healthcare
|
Reduced | 45,469 | $14,649,657 | 8.62% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
Reduced | 278,533 | $10,720,735 | 6.31% | |
| ELVN |
Enliven Therapeutics, Inc.
Healthcare
|
Reduced | 220,091 | $8,627,567 | 5.08% | |
| IONS |
Ionis Pharmaceuticals Inc
Healthcare
|
Reduced | 110,064 | $8,264,705 | 4.86% | |
| GH |
Guardant Health, Inc.
Healthcare
|
Reduced | 82,736 | $7,642,324 | 4.50% | |
| CYTK |
Cytokinetics Inc
Healthcare
|
Reduced | 103,718 | $6,836,053 | 4.02% | |
| LLY |
ELI LILLY & Co
Healthcare
|
Reduced | 7,012 | $6,449,427 | 3.79% | |
| ALMS |
Alumis Inc.
Healthcare
|
Reduced | 279,176 | $6,150,247 | 3.62% | |
| BBIO |
BridgeBio Pharma, Inc.
Healthcare
|
Reduced | 67,492 | $5,011,955 | 2.95% | |
| VERA |
Vera Therapeutics, Inc.
Healthcare
|
Reduced | 114,991 | $4,626,087 | 2.72% | |
| INSM |
INSMED Inc
Healthcare
|
NEW | 26,651 | $4,357,971 | 2.56% | |
| ELV |
Elevance Health, Inc.
Healthcare
|
Reduced | 14,677 | $4,296,691 | 2.53% | |
| AGIO |
Agios Pharmaceuticals, Inc.
Healthcare
|
Reduced | 125,060 | $4,230,779 | 2.49% | |
| UTHR |
UNITED THERAPEUTICS Corp
Healthcare
|
Reduced | 7,053 | $4,182,287 | 2.46% | |
| MLTX |
MoonLake Immunotherapeutics
Healthcare
|
NEW | 215,376 | $4,014,608 | 2.36% | |
| NTRA |
Natera, Inc.
Healthcare
|
Held | 18,650 | $3,729,813 | 2.19% | |
| RYTM |
Rhythm Pharmaceuticals, Inc.
Healthcare
|
NEW | 40,581 | $3,529,329 | 2.08% | |
| UNH |
Unitedhealth Group Inc
Healthcare
|
Added | 12,862 | $3,480,328 | 2.05% | |
| APLS |
Apellis Pharmaceuticals, Inc.
Healthcare
|
Reduced | 85,517 | $3,440,348 | 2.02% | |
| VSTM |
Verastem, Inc.
Healthcare
|
Added | 636,700 | $3,374,510 | 1.99% | |
| TXG |
10x Genomics, Inc.
Healthcare
|
Reduced | 154,194 | $3,273,538 | 1.93% | |
| BSX |
Boston Scientific Corp
Healthcare
|
NEW | 48,347 | $3,033,774 | 1.78% | |
| ALKS |
Alkermes plc.
Healthcare
|
NEW | 84,103 | $2,973,882 | 1.75% | |
| GLUE |
Monte Rosa Therapeutics, Inc.
Healthcare
|
NEW | 179,484 | $2,952,511 | 1.74% | |
| ISRG |
Intuitive Surgical Inc
Healthcare
|
Held | 6,358 | $2,930,974 | 1.72% | |
| ADAG |
Adagene Inc.
Healthcare
|
Reduced | 736,845 | $2,888,432 | 1.70% | |
| ARWR |
Arrowhead Pharmaceuticals, Inc.
Healthcare
|
Reduced | 45,721 | $2,866,706 | 1.69% | |
| CBIO |
Crescent Biopharma, Inc.
Healthcare
|
NEW | 153,191 | $2,814,118 | 1.66% | |
| RLAY |
Relay Therapeutics, Inc.
Healthcare
|
NEW | 278,302 | $2,769,104 | 1.63% | |
| MAZE |
Maze Therapeutics, Inc.
Healthcare
|
NEW | 88,510 | $2,642,023 | 1.55% | |
| CTMX |
CytomX Therapeutics, Inc.
Healthcare
|
Reduced | 521,468 | $2,450,899 | 1.44% | |
| AVTX |
Avalo Therapeutics, Inc.
Healthcare
|
NEW | 159,341 | $2,378,961 | 1.40% | |
| GKOS |
GLAUKOS Corp
Healthcare
|
Reduced | 20,874 | $2,247,294 | 1.32% | |
| CRBP |
Corbus Pharmaceuticals Holdings, Inc.
Healthcare
|
Added | 234,136 | $2,198,537 | 1.29% | |
| PEN |
Penumbra Inc
Healthcare
|
Reduced | 6,300 | $2,068,731 | 1.22% | |
| SLNO |
Soleno Therapeutics Inc
Healthcare
|
NEW | 61,673 | $2,064,812 | 1.21% | |
| LQDA |
Liquidia Corp
Healthcare
|
Reduced | 45,796 | $1,728,341 | 1.02% | |
| ZBIO |
Zenas BioPharma, Inc.
Healthcare
|
NEW | 80,730 | $1,578,271 | 0.93% | |
| NBP |
NovaBridge Biosciences
Healthcare
|
Added | 576,960 | $1,419,321 | 0.84% | |
| NXTC |
NextCure, Inc.
Healthcare
|
Reduced | 115,500 | $1,233,540 | 0.73% | |
| FDMT |
4D Molecular Therapeutics, Inc.
Healthcare
|
NEW | 130,564 | $1,215,550 | 0.72% | |
| PALI |
Palisade Bio, Inc.
Healthcare
|
Reduced | 600,000 | $1,050,000 | 0.62% | |
| ESTA |
Establishment Labs Holdings Inc.
Healthcare
|
Held | 13,100 | $743,818 | 0.44% | |
| LPCN |
Lipocine Inc.
Healthcare
|
NEW | 60,861 | $486,279 | 0.29% | |
| ABUS |
Arbutus Biopharma Corp
Healthcare
|
Held | 75,484 | $339,678 | 0.20% |