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CBIO

Crescent Biopharma, Inc.
$17.09 +0.01 (+0.06%) At close · Jul 2
Market Cap
$471.25M
Shares
27,571,935

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 60
Total Value: $482,647,729
Total Shares: 26,273,694

Institutional Ownership Trend

4 quarters

Holder Concentration

Across 60 13F filers · Δ vs Dec 31, 2025
Top Holder
16.5%
Jun 2025 → Mar 2026 · range 12.5% – 17.4%
−1.0 pts
Top 5
53.5%
Jun 2025 → Mar 2026 · range 53.5% – 57.9%
−3.1 pts
Top 10
78.5%
Jun 2025 → Mar 2026 · range 76.7% – 79.9%
+1.9 pts
HHI
780
Jun 2025 → Mar 2026 · range 780 – 863
Broadly held−44

Quarterly Activity

vs Dec 31, 2025
New
17
Increased
17
Decreased
8
Sold Out
13
Unchanged
18
Holder count: +4
Institutional value: +71.4%
Shares held: +10.7%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mid TANG CAPITAL MANAGEMENT LLC +1,447,602 2,320,000
Large Balyasny Asset Management L.P. +1,398,318 1,510,033
Mega MILLENNIUM MANAGEMENT LLC +261,671 323,553
Mega GOLDMAN SACHS GROUP INC +203,230 228,475
Large MARSHALL WACE, LLP +178,954 200,780

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid ADAR1 Capital Management, LLC −555,727 50,273
Mid PERCEPTIVE ADVISORS LLC −246,744 206,942
Mid Logos Global Management LP −117,500 482,500
Mega PRICE T ROWE ASSOCIATES INC /MD/ −34,574 303,551
Large RENAISSANCE TECHNOLOGIES LLC −22,438 24,262

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 801,395 $14,721,626
Small Exome Asset Management LLC 153,191 $2,814,118
Mega JENNISON ASSOCIATES LLC 152,974 $2,810,132
Small SILVERARC CAPITAL MANAGEMENT, LLC 130,500 $2,397,285
Large Hudson Bay Capital Management LP 88,867 $1,632,486

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 557,506 $6,612,020
Small Boxer Capital Management, LLC 453,686 $5,380,715
Large Driehaus Capital Management LLC 302,457 $3,587,140
Small HEIGHTS CAPITAL MANAGEMENT, INC 264,000 $3,131,040
Mega WELLINGTON MANAGEMENT GROUP LLP 143,412 $1,700,865
Filter: New 17 Increased 17 Reduced 8 Sold out 13 Unchanged 18
Showing 61 of 61
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega FMR LLC $75,932,651 15.73% 4,133,514
Mid BVF INC/IL $50,494,776 10.46% 2,748,763
Mid Fairmount Funds Management LLC $50,478,298 10.46% 2,747,866
Mid Venrock Adviser, LLC $39,193,791 8.12% 2,133,576
Small FCPM III SERVICES B.V. $30,822,141 6.39% 1,677,852
Large Balyasny Asset Management L.P. $27,739,306 5.75% 1,510,033
Mid Vestal Point Capital, LP $27,555,000 5.71% 1,500,000
Small Opaleye Management Inc. $24,112,737 5.00% 1,312,615
Mid TANG CAPITAL MANAGEMENT LLC $21,309,200 4.42% 1,160,000
Mid TANG CAPITAL MANAGEMENT LLC $21,309,200 4.42% 1,160,000
Mega VANGUARD CAPITAL MANAGEMENT LLC $14,721,626 3.05% 801,395
Mid Logos Global Management LP $8,863,525 1.84% 482,500
Mid Deep Track Capital, LP $8,334,211 1.73% 453,686
Large RTW INVESTMENTS, LP $6,849,364 1.42% 372,856
Small NEXTBio Capital Management LP $6,849,364 1.42% 372,856
Mega MILLENNIUM MANAGEMENT LLC $5,943,668 1.23% 323,553
Mega PRICE T ROWE ASSOCIATES INC /MD/ $5,576,231 1.16% 303,551
Large Point72 Asset Management, L.P. $5,511,000 1.14% 300,000
Large Alyeska Investment Group, L.P. $4,849,680 1.00% 264,000
Mega GOLDMAN SACHS GROUP INC $4,197,085 0.87% 228,475
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,924,474 0.81% 213,635
Mid PERCEPTIVE ADVISORS LLC $3,801,524 0.79% 206,942
Large MARSHALL WACE, LLP $3,688,328 0.76% 200,780
Small Exome Asset Management LLC $2,814,118 0.58% 153,191
Mega JENNISON ASSOCIATES LLC $2,810,132 0.58% 152,974
Small SILVERARC CAPITAL MANAGEMENT, LLC $2,397,285 0.50% 130,500
Mega TWO SIGMA INVESTMENTS, LP $2,127,760 0.44% 115,828
Mega BlackRock, Inc. $2,125,866 0.44% 115,725
Mega GEODE CAPITAL MANAGEMENT, LLC $1,914,539 0.40% 104,221
Large Hudson Bay Capital Management LP $1,632,486 0.34% 88,867
Small Stonepine Capital Management, LLC $1,561,450 0.32% 85,000
Mega UBS Group AG $1,519,309 0.31% 82,706
Large Woodline Partners LP $1,359,380 0.28% 74,000
Mid Burkehill Global Management, LP $1,359,380 0.28% 74,000
Mid ADAR1 Capital Management, LLC $923,515 0.19% 50,273
Mega VANGUARD FIDUCIARY TRUST CO Bank $907,900 0.19% 49,423
Mega JPMORGAN CHASE & CO $753,243 0.16% 41,004
Mega STATE STREET CORP $717,660 0.15% 39,067
Mega BARCLAYS PLC $554,571 0.11% 30,189
Mega BANK OF AMERICA CORP /DE/ Bank $537,818 0.11% 29,277
Mid MOORE CAPITAL MANAGEMENT, LP $459,250 0.10% 25,000
Mid Lighthouse Investment Partners, LLC $459,250 0.10% 25,000
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $457,468 0.09% 24,903
Large RENAISSANCE TECHNOLOGIES LLC $445,692 0.09% 24,262
Mega CITIGROUP INC $370,504 0.08% 20,169
Mid Brevan Howard Capital Management LP $358,766 0.07% 19,530
Mega MORGAN STANLEY $341,257 0.07% 18,577
Large OMERS ADMINISTRATION Corp $326,986 0.07% 17,800
Mega NORTHERN TRUST CORP Bank $316,496 0.07% 17,229
Mega BNP PARIBAS ARBITRAGE, SA $288,298 0.06% 15,694
Mid ALGERT GLOBAL LLC $253,616 0.05% 13,806
Micro Verdad Advisers, LP $234,180 0.05% 12,748
Micro Cannon Global Investment Management, LLC $187,374 0.04% 10,200
Mega Vanguard Global Advisers, LLC $63,725 0.01% 3,469
Mid Parallel Advisors, LLC $4,849 0.00% 264
Mid Allworth Financial LP $2,957 0.00% 161
Mid SBI Securities Co., Ltd. Broker-Dealer $1,249 0.00% 68
Mega ROYAL BANK OF CANADA Bank $936 0.00% 51
Micro Fortitude Family Office, LLC Family Office $734 0.00% 40
Large OSAIC HOLDINGS, INC. $477 0.00% 26
Small Caitong International Asset Management Co., Ltd $73 0.00% 4
Key facts CIK 1253689 CUSIP G2545C104 Visit website Investor relations

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