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CytomX Therapeutics, Inc.
$3.84 +0.03 (+0.79%) At close · Jul 7
Market Cap
$835.98M
Shares
217,702,919

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 182
Total Value: $1,048,485,225
Total Shares: 223,081,982
Showing 1–100 of 194 holdings by value · page 1 of 2

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 180 13F filers · Δ vs Dec 31, 2025
Top Holder
16.2%
Jun 2023 → Mar 2026 · range 10.4% – 20.3%
−0.7 pts
Top 5
39.3%
Jun 2023 → Mar 2026 · range 39.0% – 67.4%
−7.1 pts
Top 10
56.2%
Jun 2023 → Mar 2026 · range 56.2% – 81.9%
−8.7 pts
HHI
517
Jun 2023 → Mar 2026 · range 511 – 1,181
Broadly held−128

Quarterly Activity

vs Dec 31, 2025
New
80
Increased
60
Decreased
27
Sold Out
20
Unchanged
15
Holder count: +60
Institutional value: +65.3%
Shares held: +49.8%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega BANK OF AMERICA CORP /DE/ +9,326,480 10,202,785
Mega FMR LLC +7,267,528 31,955,637
Mid Kynam Capital Management, LP +6,047,016 15,013,093
Mega CITADEL ADVISORS LLC +5,426,389 5,899,193
Small Elmind Capital, LP +3,850,000 4,550,000

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid Venrock Adviser, LLC −5,579,376 9,982,124
Large Balyasny Asset Management L.P. −4,041,358 730,844
Mega GOLDMAN SACHS GROUP INC −1,001,105 1,459,839
Mid BOOTHBAY FUND MANAGEMENT, LLC −879,663 15,000
Mid ADAR1 Capital Management, LLC −872,579 3,410,190

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
— Longitude Capital Partners V, LLC 15,288,461 $71,855,766
— Venrock Healthcare Capital Partners III, L.P. 9,982,124 $46,915,982
Mega VANGUARD CAPITAL MANAGEMENT LLC 8,733,118 $41,045,654
Mid Nextech Invest, Ltd. 4,449,932 $20,914,680
Mega WELLINGTON MANAGEMENT GROUP LLP 3,582,985 $16,840,027

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 8,475,584 $36,105,986
Mid Commodore Capital LP 7,692,300 $32,769,198
Mid ORBIMED ADVISORS LLC 7,051,300 $30,038,538
Small Financial Engines Advisors L.L.C. 3,828,717 $16,310,334
Mid Ikarian Capital, LLC 3,172,616 $13,515,344
Filter: New 80 Increased 60 Reduced 27 Sold out 20 Unchanged 15
Showing 100 of 194
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega FMR LLC $150,191,493 14.32% 31,955,637
— Longitude Capital Partners V, LLC $71,855,766 6.85% 15,288,461
Mid Kynam Capital Management, LP $70,561,537 6.73% 15,013,093
Mega BANK OF AMERICA CORP /DE/ Bank $47,953,089 4.57% 10,202,785
Mid PERCEPTIVE ADVISORS LLC $47,464,472 4.53% 10,098,824
Mid Venrock Adviser, LLC $46,915,982 4.47% 9,982,124
— Venrock Healthcare Capital Partners III, L.P. $46,915,982 4.47% 9,982,124
Mega VANGUARD CAPITAL MANAGEMENT LLC $41,045,654 3.91% 8,733,118
Large Point72 Asset Management, L.P. $37,014,333 3.53% 7,875,390
Mega STATE STREET CORP $26,618,017 2.54% 5,663,408
Mega CITADEL ADVISORS LLC $25,409,106 2.42% 5,406,193
Mega BlackRock, Inc. $24,572,911 2.34% 5,228,280
Large BAKER BROS. ADVISORS LP $23,386,382 2.23% 4,975,826
Small Elmind Capital, LP $21,385,000 2.04% 4,550,000
Mid Nextech Invest, Ltd. $20,914,680 1.99% 4,449,932
Large MARSHALL WACE, LLP $19,449,426 1.86% 4,138,176
Mega MILLENNIUM MANAGEMENT LLC $17,202,893 1.64% 3,660,190
Mega WELLINGTON MANAGEMENT GROUP LLP $16,840,027 1.61% 3,582,985
Mid Siren, L.L.C. $16,251,241 1.55% 3,457,711
Mid ADAR1 Capital Management, LLC $16,027,893 1.53% 3,410,190
Mid Eversept Partners, LP $14,986,015 1.43% 3,188,514
Mega UBS Group AG $14,664,728 1.40% 3,120,155
Large Jefferies Financial Group Inc. $14,418,960 1.38% 3,067,864
Mega TWO SIGMA INVESTMENTS, LP $12,737,733 1.21% 2,710,156
Large Qube Research & Technologies Ltd $10,573,040 1.01% 2,249,583
Mega GEODE CAPITAL MANAGEMENT, LLC $9,713,076 0.93% 2,066,612
Large Woodline Partners LP $9,403,877 0.90% 2,000,825
Mega DIMENSIONAL FUND ADVISORS LP $9,075,322 0.87% 1,930,920
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $8,787,190 0.84% 1,869,615
Mega GOLDMAN SACHS GROUP INC $6,861,242 0.65% 1,459,839
Mid GILDER GAGNON HOWE & CO LLC $5,265,452 0.50% 1,120,309
Mega VANGUARD FIDUCIARY TRUST CO Bank $5,183,550 0.49% 1,102,883
Small Patient Square Capital LP $5,103,213 0.49% 1,085,790
Small Seven Fleet Capital Management LP $5,101,370 0.49% 1,085,398
Mega JANE STREET GROUP, LLC $4,688,296 0.45% 997,510
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $4,266,660 0.41% 907,800
Mid EVENTIDE ASSET MANAGEMENT, LLC $4,230,000 0.40% 900,000
Small Ally Bridge Group (NY) LLC $4,230,000 0.40% 900,000
Large Caption Management, LLC $4,230,000 0.40% 900,000
Large Trexquant Investment LP $4,224,204 0.40% 898,767
Large Balyasny Asset Management L.P. $3,434,966 0.33% 730,844
Mid DV Trading LLC $3,355,800 0.32% 714,000
Mega BARCLAYS PLC $3,290,000 0.31% 700,000
Mega NORTHERN TRUST CORP Bank $2,877,061 0.27% 612,141
Mega BNP PARIBAS ARBITRAGE, SA $2,849,492 0.27% 606,275
Large Ensign Peak Advisors, Inc $2,784,623 0.27% 592,473
Large Caption Management, LLC $2,694,152 0.26% 573,224
Mega FIRST TRUST ADVISORS LP $2,672,241 0.25% 568,562
Small Informed Momentum Co LLC $2,656,031 0.25% 565,113
Mid Longaeva Partners L.P. $2,585,000 0.25% 550,000
Small Velan Capital Investment Management LP $2,538,000 0.24% 540,000
Small Exome Asset Management LLC $2,450,899 0.23% 521,468
Mega MORGAN STANLEY $2,446,324 0.23% 520,495
Small SCHULHOFF & CO INC $2,244,485 0.21% 477,550
Mega DEUTSCHE BANK AG\ Bank $2,178,078 0.21% 463,421
Mid 683 Capital Management, LLC $1,997,500 0.19% 425,000
Large Caption Management, LLC $1,974,000 0.19% 420,000
Mega RAYMOND JAMES FINANCIAL INC $1,786,752 0.17% 380,160
Small Seven Fleet Capital Management LP $1,745,570 0.17% 371,398
Large Assenagon Asset Management S.A. $1,711,613 0.16% 364,173
Mega CITADEL ADVISORS LLC $1,675,080 0.16% 356,400
Mid SEVEN GRAND MANAGERS, LLC $1,527,500 0.15% 325,000
Mega Swiss National Bank Bank $1,502,120 0.14% 319,600
Small DIADEMA PARTNERS LP $1,485,200 0.14% 316,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,421,750 0.14% 302,500
Mid Soleus Capital Management, L.P. $1,410,000 0.13% 300,000
Mega Bank of New York Mellon Corp Bank $1,362,378 0.13% 289,868
Small HighVista Strategies LLC $1,353,867 0.13% 288,057
Mid Brevan Howard Capital Management LP $1,265,249 0.12% 269,202
Mid SIMPLEX TRADING, LLC $1,167,658 0.11% 248,438
Large SEI INVESTMENTS CO $1,166,765 0.11% 248,248
Large Tidal Investments LLC $1,155,109 0.11% 245,768
Large Squarepoint Ops LLC $1,133,710 0.11% 241,215
Large Rafferty Asset Management, LLC $1,127,172 0.11% 239,824
Large LMR Partners LLP $1,104,175 0.11% 234,931
Small Scientech Research LLC $1,083,810 0.10% 230,598
Small DAFNA Capital Management LLC $1,081,000 0.10% 230,000
Mid Tema ETFs LLC Mutual Fund $1,069,273 0.10% 227,505
Mid Burkehill Global Management, LP $1,057,500 0.10% 225,000
Small SPHERA FUNDS MANAGEMENT LTD. $1,034,000 0.10% 220,000
Small Stonepine Capital Management, LLC $940,000 0.09% 200,000
Small Stonepine Capital Management, LLC $940,000 0.09% 200,000
Large Centiva Capital, LP $940,000 0.09% 200,000
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $890,180 0.08% 189,400
Mid Y-Intercept (Hong Kong) Ltd $787,315 0.08% 167,514
Mid GROUP ONE TRADING LLC $724,429 0.07% 154,134
Small AWM Investment Company, Inc. $705,000 0.07% 150,000
Mega BARCLAYS PLC $669,335 0.06% 142,412
Mega Legal & General Group Plc $666,896 0.06% 141,893
Mega CITADEL ADVISORS LLC $642,020 0.06% 136,600
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $605,341 0.06% 128,796
Mega VANGUARD ASSET MANAGEMENT, Ltd $577,597 0.06% 122,893
Mega LPL Financial LLC $576,379 0.05% 122,634
Mid PRELUDE CAPITAL MANAGEMENT, LLC $572,986 0.05% 121,912
Mid NLB Skladi, upravljanje premozenja, d.o.o. $522,221 0.05% 111,111
Mega CANADA PENSION PLAN INVESTMENT BOARD Pension $511,360 0.05% 108,800
Large ALPS ADVISORS INC $497,354 0.05% 105,820
Large Jain Global LLC $492,325 0.05% 104,750
Mid PROFUND ADVISORS LLC $491,314 0.05% 104,535
Micro Aspire Growth Partners LLC $480,593 0.05% 102,254
Key facts CIK 1501989 CUSIP 23284F105 Visit website Investor relations

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