Ishara Investments LP

CIK

2111609

Location

LOS ANGELES, CA

Portfolio Value

Small $138,332,953

Diversification

Diversified

Filing Date

Global Rank

#7,642 / 8,794 ▲ 269 · as of Jun 2026

Top Industry

Biotechnology 93.0%

Period ended 3 months ago

Filed Aug 14, 2026 · 51d

3 quarters · since Dec 2025

Clone Performance

Build a hypothetical price-return history from this filer's public 13F holdings.

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Portfolio Concentration

41 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

7.5%

−7.5 pts

Top 5

30.9%

−7.7 pts

Top 10

50.6%

−6.3 pts

HHI

384

Diversified−148

Portfolio Trend

3 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$138,332,953	41

Last Quarter's Activity

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Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

13 positions

Ticker	Company	Δ Shares	Shares	Value
ANNX	Annexon, Inc.	+645,750	820,000	$4,682,200
LXRX	Lexicon Pharmaceuticals, Inc.	+369,000	1,271,000	$3,050,400
ACAD	Acadia Pharmaceuticals Inc	+287,000	410,000	$10,373,000
XERS	Xeris Biopharma Holdings, Inc.	+205,000	1,230,000	$9,741,600
DBVT	DBV Technologies S.A.	+82,000	184,500	$3,025,800
SION	Sionna Therapeutics, Inc.	+73,800	123,000	$5,410,770
CTNM	Contineum Therapeutics, Inc.	+63,000	205,000	$3,359,950
BMRN	Biomarin Pharmaceutical Inc	+61,500	143,500	$8,211,070
RARE	Ultragenyx Pharmaceutical Inc.	+30,750	205,000	$6,844,950
PCVX	Vaxcyte, Inc.	+24,600	82,000	$4,766,660
MLYS	Mineralys Therapeutics, Inc.	+20,500	102,500	$2,765,450
ORIC	Oric Pharmaceuticals, Inc.	+20,500	123,000	$1,332,090
GMAB	Genmab A/S	+20,500	102,500	$2,815,675
No positions match the current search.

Trimmed

Positions the filer reduced

9 positions

Ticker	Company	Δ Shares	Shares	Value
ZNTL	Zentalis Pharmaceuticals, Inc.	−205,000	1,025,000	$4,971,250
IMTX	Immatics N.V.	−123,000	30,750	$311,497
SLN	Silence Therapeutics plc	−85,150	55,350	$607,743
VERA	Vera Therapeutics, Inc.	−71,750	10,250	$439,827
TVTX	Travere Therapeutics, Inc.	−28,700	82,000	$4,658,420
SRRK	Scholar Rock Holding Corp	−26,650	30,750	$1,691,250
AXSM	Axsome Therapeutics, Inc.	−24,600	16,400	$4,014,228
PRAX	Praxis Precision Medicines, Inc.	−20,500	22,550	$7,549,514
BEAM	Beam Therapeutics Inc.	−16,400	41,000	$1,407,120
No positions match the current search.

New Positions

Positions the filer opened this quarter

16 positions

Ticker	Company	Shares	Value
AGIO	Agios Pharmaceuticals, Inc.	164,000	$6,086,040
INSM	INSMED Inc	51,250	$5,464,275
—		143,500	$5,369,770
TNXP	Tonix Pharmaceuticals Holding Corp.	338,250	$4,316,070
BBIO	BridgeBio Pharma, Inc.	57,400	$4,275,152
KURA	Kura Oncology, Inc.	276,750	$3,035,947
CYTK	Cytokinetics Inc	32,800	$2,794,232
NUVB	Nuvation Bio Inc.	369,000	$2,095,920
WVE	Wave Life Sciences, Inc.	328,000	$1,905,680
NKTR	Nektar Therapeutics	26,650	$1,860,436
ELVN	Enliven Therapeutics, Inc.	32,800	$1,664,600
VRTX	Vertex Pharmaceuticals Inc / Ma	2,460	$1,221,955
SPRY	ARS Pharmaceuticals, Inc.	143,490	$1,149,354
MNPR	Monopar Therapeutics	12,300	$1,138,857
ERAS	Erasca, Inc.	41,000	$751,120
MREO	Mereo BioPharma Group plc	768,750	$244,462
No positions match the current search.

Sold Out

Positions the filer fully exited

11 positions

Ticker	Company	Shares	Value
VSTM	Verastem, Inc.	820,000	$4,346,000
ARWR	Arrowhead Pharmaceuticals, Inc.	55,350	$3,470,445
MLTX	MoonLake Immunotherapeutics	174,250	$3,248,020
ARDX	Ardelyx, Inc.	451,000	$2,701,490
LGND	Ligand Pharmaceuticals Inc	8,200	$1,637,130
EWTX	Edgewise Therapeutics, Inc.	49,200	$1,549,800
IDYA	IDEAYA Biosciences, Inc.	24,600	$819,672
PTCT	Ptc Therapeutics, Inc.	10,250	$698,332
—		82,000	$0
—		369,000	$0
—		276,750	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

41 tracked positions · $138,332,953 total · filing declares 41 positions · $136,099,277 · as of Jun 30, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
ACAD	Acadia Pharmaceuticals Inc Healthcare	Added	410,000	+287,000	$10,373,000	+278.9%	7.50%
XERS	Xeris Biopharma Holdings, Inc. Healthcare	Added	1,230,000	+205,000	$9,741,600	+63.9%	7.04%
BMRN	Biomarin Pharmaceutical Inc Healthcare	Added	143,500	+61,500	$8,211,070	+77.3%	5.94%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Reduced	22,550	-20,500	$7,549,514	−45.6%	5.46%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	Added	205,000	+30,750	$6,844,950	+87.5%	4.95%
AGIO	Agios Pharmaceuticals, Inc. Healthcare	NEW	164,000	NEW	$6,086,040	NEW	4.40%
INSM	INSMED Inc Healthcare	NEW	51,250	NEW	$5,464,275	NEW	3.95%
SION	Sionna Therapeutics, Inc. Healthcare	Added	123,000	+73,800	$5,410,770	+174.3%	3.91%
		NEW	143,500	NEW	$5,369,770	NEW	3.88%
ZNTL	Zentalis Pharmaceuticals, Inc. Healthcare	Reduced	1,025,000	-205,000	$4,971,250	+72.7%	3.59%
PCVX	Vaxcyte, Inc. Healthcare	Added	82,000	+24,600	$4,766,660	+42.9%	3.45%
ANNX	Annexon, Inc. Healthcare	Added	820,000	+645,750	$4,682,200	+385.0%	3.38%
TVTX	Travere Therapeutics, Inc. Healthcare	Reduced	82,000	-28,700	$4,658,420	+41.6%	3.37%
TNXP	Tonix Pharmaceuticals Holding Corp. Healthcare	NEW	338,250	NEW	$4,316,070	NEW	3.12%
BBIO	BridgeBio Pharma, Inc. Healthcare	NEW	57,400	NEW	$4,275,152	NEW	3.09%
AXSM	Axsome Therapeutics, Inc. Healthcare	Reduced	16,400	-24,600	$4,014,228	−42.1%	2.90%
CTNM	Contineum Therapeutics, Inc. Healthcare	Added	205,000	+63,000	$3,359,950	+81.2%	2.43%
LXRX	Lexicon Pharmaceuticals, Inc. Healthcare	Added	1,271,000	+369,000	$3,050,400	+116.8%	2.21%
KURA	Kura Oncology, Inc. Healthcare	NEW	276,750	NEW	$3,035,947	NEW	2.19%
DBVT	DBV Technologies S.A. Healthcare	Added	184,500	+82,000	$3,025,800	+41.3%	2.19%
GMAB	Genmab A/S Healthcare	Added	102,500	+20,500	$2,815,675	+28.0%	2.04%
CYTK	Cytokinetics Inc Healthcare	NEW	32,800	NEW	$2,794,232	NEW	2.02%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Added	102,500	+20,500	$2,765,450	+24.5%	2.00%
NUVB	Nuvation Bio Inc. Healthcare	NEW	369,000	NEW	$2,095,920	NEW	1.52%
WVE	Wave Life Sciences, Inc. Healthcare	NEW	328,000	NEW	$1,905,680	NEW	1.38%
NKTR	Nektar Therapeutics Healthcare	NEW	26,650	NEW	$1,860,436	NEW	1.34%
SRRK	Scholar Rock Holding Corp Healthcare	Reduced	30,750	-26,650	$1,691,250	−40.1%	1.22%
ELVN	Enliven Therapeutics, Inc. Healthcare	NEW	32,800	NEW	$1,664,600	NEW	1.20%
ALNY	Alnylam Pharmaceuticals, Inc. Healthcare	Held	5,125	0	$1,542,778	−9.0%	1.12%
BEAM	Beam Therapeutics Inc. Healthcare	Reduced	41,000	-16,400	$1,407,120	+2.9%	1.02%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	Added	123,000	+20,500	$1,332,090	+2.6%	0.96%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	Held	36,900	0	$1,250,541	+5.9%	0.90%
VRTX	Vertex Pharmaceuticals Inc / Ma Healthcare	NEW	2,460	NEW	$1,221,955	NEW	0.88%
SPRY	ARS Pharmaceuticals, Inc. Healthcare	NEW	143,490	NEW	$1,149,354	NEW	0.83%
MNPR	Monopar Therapeutics Healthcare	NEW	12,300	NEW	$1,138,857	NEW	0.82%
ERAS	Erasca, Inc. Healthcare	NEW	41,000	NEW	$751,120	NEW	0.54%
SLN	Silence Therapeutics plc Healthcare	Reduced	55,350	-85,150	$607,743	−17.9%	0.44%
VERA	Vera Therapeutics, Inc. Healthcare	Reduced	10,250	-71,750	$439,827	−86.7%	0.32%
IMTX	Immatics N.V. Healthcare	Reduced	30,750	-123,000	$311,497	−79.4%	0.23%
MREO	Mereo BioPharma Group plc Healthcare	NEW	768,750	NEW	$244,462	NEW	0.18%
GOSS	Gossamer Bio, Inc. Healthcare	Held	820,000	0	$135,300	−49.8%	0.10%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.