Boxer Capital Management, LLC

CIK

2018299

Location

San Diego, CA

Portfolio Value

Small $753,318,362

Diversification

Diversified

Filing Date

Global Rank

#2,089 / 8,622 ▲ 791 · as of Mar 2026

Top Industry

Biotechnology 98.2%

3Y Alpha vs SPY

+88.9%

Period ended 4 months ago

Filed May 15, 2026 · 2mo

6 quarters · since Dec 2024

Clone Performance

Feb 2025–Jul 2026 · vs SPY

Hypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.

Cloned portfolio

+181.8%

SPY

+23.3%

Annualised alpha

+88.7%

Max drawdown

−33.8%

Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. It tracks 100% of reported value on average across 6 quarters. Past performance does not predict future results.

Portfolio Concentration

52 tracked positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025

Top Position

30.2%

+8.2 pts

Top 5

50.6%

+3.0 pts

Top 10

64.0%

−0.9 pts

HHI

1,111

Diversified+343

Portfolio Trend

6 quarters · across all stocks

Sector Breakdown

As of Mar 31, 2026

Sector	% Portfolio	Value	Positions
Healthcare	99.7%	$750,964,214	51
Consumer Defensive	0.3%	$2,354,148	1

Last Quarter's Activity

Export CSV

Mar 31, 2026 vs Dec 31, 2025

Added To

Positions the filer increased

13 positions

Ticker	Company	Δ Shares	Shares	Value
PGEN	Precigen, Inc.	+2,125,000	3,500,000	$13,545,000
VIR	Vir Biotechnology, Inc.	+1,241,000	1,866,000	$16,719,360
ZURA	Zura Bio Ltd	+850,000	900,000	$5,355,000
REPL	Replimune Group, Inc.	+425,000	1,175,000	$8,988,750
QURE	uniQure N.V.	+372,000	662,000	$10,823,700
SRZN	Surrozen, Inc./DE	+350,168	766,318	$22,322,843
CLNN	Clene Inc.	+277,778	477,515	$2,354,148
CAPR	Capricor Therapeutics, Inc.	+265,000	590,000	$17,936,000
KOD	Kodiak Sciences Inc.	+225,000	1,361,000	$51,881,320
RVMD	Revolution Medicines, Inc.	+100,000	500,000	$48,625,000
ABVX	Abivax S.A.	+75,000	200,000	$22,270,000
KPTI	Karyopharm Therapeutics Inc.	+50,000	302,536	$1,685,125
AVTX	Avalo Therapeutics, Inc.	+25,000	300,000	$4,479,000
No positions match the current search.

Trimmed

Positions the filer reduced

3 positions

Ticker	Company	Δ Shares	Shares	Value
PEPG	PepGen Inc.	−101,000	272,892	$483,018
HELP	Cybin Inc.	−75,000	640,000	$3,072,000
INO	Inovio Pharmaceuticals, Inc.	−50,000	2,370,122	$4,124,012
No positions match the current search.

New Positions

Positions the filer opened this quarter

12 positions

Ticker	Company	Shares	Value
PCVX	Vaxcyte, Inc.	325,000	$18,885,750
CRVS	Corvus Pharmaceuticals, Inc.	1,100,000	$16,093,000
DFTX	Definium Therapeutics, Inc.	598,500	$11,311,650
IRD	Opus Genetics, Inc.	2,250,000	$10,237,500
CORT	Corcept Therapeutics Inc	250,000	$10,077,500
SLNO	Soleno Therapeutics Inc	200,000	$6,696,000
ALLO	Allogene Therapeutics, Inc.	2,725,000	$6,649,000
RLMD	Relmada Therapeutics, Inc.	842,106	$5,861,057
OCUL	Ocular Therapeutix, Inc	350,000	$2,964,500
ANTX	AN2 Therapeutics, Inc.	749,035	$2,561,699
ORIC	Oric Pharmaceuticals, Inc.	176,500	$2,236,255
RGNX	REGENXBIO Inc.	15,000	$125,700
No positions match the current search.

Sold Out

Positions the filer fully exited

1 positions

Ticker	Company	Shares	Value	Open
CBIO	Crescent Biopharma, Inc.	453,686	$5,380,715
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

52 tracked positions · $753,318,362 total · as of Mar 31, 2026

All sectors Consumer Defensive Healthcare

Showing 1–50 of 52 positions by value · page 1 of 2

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
TNGX	Tango Therapeutics, Inc. Healthcare	Held	10,876,219	0	$227,530,501	+136.1%	30.20%
KOD	Kodiak Sciences Inc. Healthcare	Added	1,361,000	+225,000	$51,881,320	+63.3%	6.89%
RVMD	Revolution Medicines, Inc. Healthcare	Added	500,000	+100,000	$48,625,000	+52.6%	6.45%
KYMR	Kymera Therapeutics, Inc. Healthcare	Held	329,100	0	$27,410,739	+7.0%	3.64%
CELC	Celcuity Inc. Healthcare	Held	225,000	0	$25,681,500	+14.4%	3.41%
SRZN	Surrozen, Inc./DE Healthcare	Added	766,318	+350,168	$22,322,843	+137.4%	2.96%
ABVX	Abivax S.A. Healthcare	Added	200,000	+75,000	$22,270,000	+32.1%	2.96%
TERN	Terns Pharmaceuticals, Inc. Healthcare	Held	375,000	0	$19,770,000	+30.5%	2.62%
PCVX	Vaxcyte, Inc. Healthcare	NEW	325,000	NEW	$18,885,750	NEW	2.51%
CAPR	Capricor Therapeutics, Inc. Healthcare	Added	590,000	+265,000	$17,936,000	+91.2%	2.38%
PTGX	Protagonist Therapeutics, Inc Healthcare	Held	170,000	0	$17,918,000	+20.7%	2.38%
VIR	Vir Biotechnology, Inc. Healthcare	Added	1,866,000	+1,241,000	$16,719,360	+343.6%	2.22%
CRVS	Corvus Pharmaceuticals, Inc. Healthcare	NEW	1,100,000	NEW	$16,093,000	NEW	2.14%
PRAX	Praxis Precision Medicines, Inc. Healthcare	Held	46,457	0	$14,967,980	+9.3%	1.99%
PTCT	Ptc Therapeutics, Inc. Healthcare	Held	200,000	0	$13,626,000	−10.3%	1.81%
PGEN	Precigen, Inc. Healthcare	Added	3,500,000	+2,125,000	$13,545,000	+135.7%	1.80%
DFTX	Definium Therapeutics, Inc. Healthcare	NEW	598,500	NEW	$11,311,650	NEW	1.50%
AMLX	Amylyx Pharmaceuticals, Inc. Healthcare	Held	800,000	0	$11,120,000	+15.1%	1.48%
QURE	uniQure N.V. Healthcare	Added	662,000	+372,000	$10,823,700	+56.0%	1.44%
IRD	Opus Genetics, Inc. Healthcare	NEW	2,250,000	NEW	$10,237,500	NEW	1.36%
CORT	Corcept Therapeutics Inc Healthcare	NEW	250,000	NEW	$10,077,500	NEW	1.34%
URGN	UroGen Pharma Ltd. Healthcare	Held	500,000	0	$8,990,000	−23.2%	1.19%
REPL	Replimune Group, Inc. Healthcare	Added	1,175,000	+425,000	$8,988,750	+23.3%	1.19%
COGT	Cogent Biosciences, Inc. Healthcare	Held	225,000	0	$8,660,250	+8.4%	1.15%
PALI	Palisade Bio, Inc. Healthcare	Held	4,799,875	0	$8,399,781	−25.5%	1.12%
SLNO	Soleno Therapeutics Inc Healthcare	NEW	200,000	NEW	$6,696,000	NEW	0.89%
ALLO	Allogene Therapeutics, Inc. Healthcare	NEW	2,725,000	NEW	$6,649,000	NEW	0.88%
CYTK	Cytokinetics Inc Healthcare	Held	100,000	0	$6,591,000	+3.7%	0.87%
CTNM	Contineum Therapeutics, Inc. Healthcare	Held	494,000	0	$6,451,640	+14.3%	0.86%
APGE	Apogee Therapeutics, Inc. Healthcare	Held	70,000	0	$5,891,900	+11.5%	0.78%
RLMD	Relmada Therapeutics, Inc. Healthcare	NEW	842,106	NEW	$5,861,057	NEW	0.78%
ZURA	Zura Bio Ltd Healthcare	Added	900,000	+850,000	$5,355,000	+1943.9%	0.71%
MLTX	MoonLake Immunotherapeutics Healthcare	Held	275,000	0	$5,126,000	+41.4%	0.68%
AVTX	Avalo Therapeutics, Inc. Healthcare	Added	300,000	+25,000	$4,479,000	−10.3%	0.59%
INO	Inovio Pharmaceuticals, Inc. Healthcare	Reduced	2,370,122	-50,000	$4,124,012	−2.1%	0.55%
GPCR	Structure Therapeutics Inc. Healthcare	Held	75,000	0	$3,615,000	−30.7%	0.48%
SRPT	Sarepta Therapeutics, Inc. Healthcare	Held	150,000	0	$3,264,000	+1.1%	0.43%
HELP	Cybin Inc. Healthcare	Reduced	640,000	-75,000	$3,072,000	−47.5%	0.41%
OCUL	Ocular Therapeutix, Inc Healthcare	NEW	350,000	NEW	$2,964,500	NEW	0.39%
ANTX	AN2 Therapeutics, Inc. Healthcare	NEW	749,035	NEW	$2,561,699	NEW	0.34%
CLNN	Clene Inc. Consumer Defensive	Added	477,515	+277,778	$2,354,148	+100.8%	0.31%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	NEW	176,500	NEW	$2,236,255	NEW	0.30%
SLDB	Solid Biosciences Inc. Healthcare	Held	300,000	0	$2,160,000	+27.7%	0.29%
IVVD	Invivyd, Inc. Healthcare	Held	1,500,000	0	$1,950,000	−47.4%	0.26%
LBRX	Lb Pharmaceuticals Inc Healthcare	Held	70,000	0	$1,726,200	+10.8%	0.23%
KPTI	Karyopharm Therapeutics Inc. Healthcare	Added	302,536	+50,000	$1,685,125	−9.3%	0.22%
NRIX	Nurix Therapeutics, Inc. Healthcare	Held	100,000	0	$1,550,000	−18.3%	0.21%
UPB	Upstream Bio, Inc. Healthcare	Held	150,000	0	$1,350,000	−66.9%	0.18%
MIST	Milestone Pharmaceuticals Inc. Healthcare	Held	666,666	0	$793,332	−41.1%	0.11%
PEPG	PepGen Inc. Healthcare	Reduced	272,892	-101,000	$483,018	−80.2%	0.06%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.